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19 Possible Causes for Massive Splenomegaly, Pancytopenia, Pulmonary Cryptococcosis

  • Chronic Lymphocytic Leukemia

    splenomegaly and occasionally lymphadenopathy; prognosis is often poor.[medical-dictionary.thefreedictionary.com] Brentuximab vedotin had a transient effect, but the patient died of sepsis due to residual PTCL and pancytopenia.[ncbi.nlm.nih.gov] The symptoms of this infection range from a silent infection to fever, enlargement of the liver and spleen, weight loss, and pancytopenia.[ncbi.nlm.nih.gov]

  • Hairy Cell Leukemia

    Also these cytokines may play a role in the development of hairy cell leukemia.Key words: hairy cell leukemia -  sarcoidosis - massive splenomegaly.[ncbi.nlm.nih.gov] During the preoperative evaluation, pancytopenia was detected.[ncbi.nlm.nih.gov] Hairy cell leukemia typically presents with pancytopenia and often mimics aplastic anemia.[ncbi.nlm.nih.gov]

  • Chronic Myeloid Leukemia

    Here, we report a case of aCMLin a 5-month baby who presented with massive splenomegaly. The diagnosis was in accordance with the WHO criteria established in 2008.[ncbi.nlm.nih.gov] We present a case of 29-year-old white male farmer, with chronic myeloid leukemia treated with imatinib who developed significant pancytopenia, leading to discontinuation[ncbi.nlm.nih.gov] Chronic myeloid leukemia (CML) is a chronic myeloproliferative disorder that usually presents with high white blood cell counts and massive splenomegaly.[ncbi.nlm.nih.gov]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    […] included thrombocytopenia (n 8), diarrhea (n 3), alanine aminotransferase elevation (n 3), aspartate aminotransferase elevation (n 2), dyspnea (n 2), neutropenia (n 2), pancytopenia[bloodjournal.org]

  • Chronic Phase of Chronic Myeloid Leukemia

    Shima H 1, 2 , Kiyokawa N 3 , Miharu M 3 , Tanizawa A 4 , Kurosawa H 5 , Watanabe A 6 , Ito M 7 , Tono C 8 , Yuza Y 9 , Muramatsu H 10 , Hotta N 11 , Okada M 12 , Hamamoto K 13 , Kajiwara R 14 , Saito AM 2 , Horibe K 2 , Mizutani S 15 , Adachi S 16 , Ishii E 17 , Shimada H 1 . Author information 1 Department of Pediatrics,[…][ncbi.nlm.nih.gov]

  • Non-Hodgkin Lymphoma

    […] antibiotic therapy may result in remission of the disease.[ 97 ] Splenic marginal zone lymphoma Splenic marginal zone lymphoma is an indolent lymphoma that is marked by massive[web.archive.org] Leukemia commonly occurring after alkylating agent treatment; manifestations include pancytopenia, megaloblastic bone marrow, and nucleated red cells in peripheral marrow;[icd9data.com] […] suspected NHL should include the following: CBC count: May be normal in early-stage disease; in more advanced stages, may demonstrate anemia, thrombocytopenia/leukopenia/pancytopenia[emedicine.com]

  • Disseminated Tuberculosis

    We report a case of cryptococcosis with pulmonary involvement in a patient with coexisting disseminated TB in HIV infection.[ncbi.nlm.nih.gov] He was treated with folic acid and ferrous sulphate for iron deficiency anaemia but in view of hepatomegaly and massive splenomegaly and hypersplenism, he was referred to[jpma.org.pk] The purpose of this paper is to record a case of pancytopenia due to disseminated tuberculosis, and again to draw attention to the difficulties encountered in diagnosis.[annals.org]

  • Sarcoidosis

    The laboratory investigations showed pancytopenia, and imaging tests revealed hepatosplenomegaly and ascites.[ncbi.nlm.nih.gov] In isolated cases, hypersplenism causes various grades of anaemia leuko-penia, thrombocytopenia, to severe conditions including pancytopenia.[pneumologia.eu] […] erythema nodosum, and hilar adenopathy) Hematologic 5–30% Lymphocytopenia Anemia of chronic disease Anemia due to granulomatous infiltration of bone marrow, sometimes causing pancytopenia[merckmanuals.com]

  • Hodgkin Lymphoma

    […] pain in the lumbosacral region associated with elevated levels of lactate dehydrogenase (LDH), fibrin degradation products (D-Dimer), and alkaline phosphatase as well as pancytopenia[ncbi.nlm.nih.gov]

  • Blast Phase

    The findings of massive splenomegaly, basophilia, and thrombocytosis point toward CML. Our patient had massive splenomegaly and basophilia but a normal platelet count.[ecancer.org] Pretherapy with enasidenib: peripheral smear shows pancytopenia with circulating blasts.[bloodjournal.org] Laboratory testing revealed pancytopenia, with a WBC count of 2,590 μl (normal range, 4,500–11,000 μl), a hemoglobin concentration of 8.4 g/dl (normal range, 11.3–15.3 g/dl[spandidos-publications.com]

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