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424 Possible Causes for Massive Splenomegaly, Small Testicular Volume

  • Sarcoidosis

    Computed tomography detected a nodule in the middle lobe of the right lung, multiple small volume nodes in the retrocaval and left para-aortic regions, and enlarged bilateral[ncbi.nlm.nih.gov] Scrotal ultrasonography demonstrated multiple bilateral hypoechoic testicular lesions that were of similar size and distributed unusually throughout the testicular parenchyma[ncbi.nlm.nih.gov] […] external iliac and inguinal nodes, similar to those found in metastatic testicular cancer.[ncbi.nlm.nih.gov]

  • Non-Hodgkin Lymphoma

    […] antibiotic therapy may result in remission of the disease.[ 97 ] Splenic marginal zone lymphoma Splenic marginal zone lymphoma is an indolent lymphoma that is marked by massive[web.archive.org] […] antibiotic therapy may result in remission of the disease.[ 108 ] Splenic marginal zone lymphoma Splenic marginal zone lymphoma is an indolent lymphoma that is marked by massive[cancer.gov] splenomegaly and peripheral blood and bone marrow involvement, usually without adenopathy.[ 98 - 100 ] This type of lymphoma is otherwise known as splenic lymphoma with villous[web.archive.org]

    Missing: Small Testicular Volume
  • Leukemia

    Splenomegaly can be massive, consistency high, with the fibrous thickening of the capsule.[ncbi.nlm.nih.gov] In cats, vomiting and splenomegaly, gastric and duodenal ulcers are found, with the presence of mastocytoid neoplasms.[ncbi.nlm.nih.gov] The anemia is due in part to massive destruction of erythroid cells within the malignant histiocytes, although an associated concurrent erythroid suppression cannot be excluded[ncbi.nlm.nih.gov]

    Missing: Small Testicular Volume
  • Lymphoma

    T-cell CLL usually is a more aggressive disorder than B-cell CLL, with massive splenomegaly, marked neutropenia, skin infiltration, modest bone marrow infiltration, and a[web.archive.org]

    Missing: Small Testicular Volume
  • Primary Myelofibrosis

    She also underwent splenectomy when she was 13 years old, due to massive splenomegaly, anemia and various infection disease episodes.[ncbi.nlm.nih.gov] Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by progressive anemia, massive splenomegaly, leukoerythroblastosis, extramedullary hematopoiesis[ncbi.nlm.nih.gov] Treatment may include hydroxyurea for thrombocytosis and massive splenomegaly, androgens, erythropoietin, or red cell transfusions for severe anemia, local irradiation of[accessmedicine.mhmedical.com]

    Missing: Small Testicular Volume
  • Hepatosplenic Lymphoma

    Most patients had massive splenomegaly, and bone marrow showed sinusoidal involvement by lymphoma.[mdanderson.elsevierpure.com] A CT scan revealed a liver with cirrhotic changes without focal lesions and massive splenomegaly with axillary, retroperitoneal and inguinal lymphadenopathy ( Figure 1 ).[jgo.amegroups.com] Figure 1 A coronal view of the chest and abdomen obtained with the administration of contrast material, shows a cirrhotic liver with massive splenomegaly Notably, the patient[jgo.amegroups.com]

    Missing: Small Testicular Volume
  • Gaucher Disease

    CONCLUSION: HALS for GD patients with refractory hypersplenism and massive splenomegaly is safe and feasible in experienced hands.[ncbi.nlm.nih.gov] Although Gaucher disease generally presents with massive splenomegaly, which one of the predisposing causes of a wandering spleen, literature shows only one report of a wandering[ncbi.nlm.nih.gov] Here we present a 36 year old male patient presenting with hip pain showing bilateral avascular necrosis of femoral head with massive splenomegaly and on evaluation, showed[ncbi.nlm.nih.gov]

    Missing: Small Testicular Volume
  • Chronic Lymphocytic Leukemia

    splenomegaly and occasionally lymphadenopathy; prognosis is often poor.[medical-dictionary.thefreedictionary.com] Bulky disease was defined as the presence of lymph-nodes more than 5 cm in longest diameter by CT and/or ultrasound examination or the presence of massive splenomegaly (6[mjhid.org] […] or rapidly progressive splenomegaly uncontrolled autoimmune cytopenias rapid lymphocyte doubling time: either occurring in less than 6 months or when there is an increase[radiopaedia.org]

    Missing: Small Testicular Volume
  • Splenic Vein Thrombosis

    Routine ultrasound examination in the fourth month of the pregnancy revealed massive splenomegaly of unknown origin.[ncbi.nlm.nih.gov] Seven of 9 patients (78 %) with massive splenomegaly ( 20 cm) developed PSVT compared with 4 of 13 patients (31 %) with moderate splenomegaly (15-20 cm) and 6 of 45 patients[ncbi.nlm.nih.gov] Other causes Increased hepatic blood flow: Increased splenic blood flow - eg, massive splenomegaly. Hepatoportal arteriovenous fistula.[patient.info]

    Missing: Small Testicular Volume
  • Myeloproliferative Disease

    Splenomegaly, sometimes massive, is a characteristic finding. Symptoms include the following: Splenic pain. Early satiety. Anemia. Bone pain. Fatigue. Fever.[northshore.org] When patients are poorly compliant with phlebotomy or issues of massive splenomegaly, leukocytosis, or thrombocytosis supervene, treatment with interferon or pegylated interferon[northshore.org] splenomegaly, a high phlebotomy requirement, or excessive thrombocytosis.[ 13 ] In a pooled analysis of 16 different trials, interferon-alpha therapy resulted in avoidance[northshore.org]

    Missing: Small Testicular Volume

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