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5,775 Possible Causes for Massive Splenomegaly, Small Testicular Volume, Weight Gain

  • Sarcoidosis

    For individual end-points, weight gain (HR 2.04) and new hypertension (HR 3.36) were associated with any use of GC.[ncbi.nlm.nih.gov] Computed tomography detected a nodule in the middle lobe of the right lung, multiple small volume nodes in the retrocaval and left para-aortic regions, and enlarged bilateral[ncbi.nlm.nih.gov] gain Surgery In the rare situation when sarcoidosis has severely damaged your lungs, organ transplantation may be necessary.[brighamandwomens.org]

  • Hypogonadotropic Hypogonadism

    gain or weight loss) Long-term (chronic) medical diseases, including chronic inflammation or infections Drug use, such as heroin or use or abuse of prescription opiate medicines[medlineplus.gov] All patients with AHH had undergone splenectomy due to hypersplenism and/or massive splenomegaly, versus 50% of the control group.[mjhid.org] Cryptorchid or maldescended testes and small testicular volume are clinical hallmarks of congenital hypogonadotropic hypogonadism (CHH) [ 1 ].[ijpeonline.biomedcentral.com]

  • Autosomal Dominant Autoimmune Lymphoproliferative Syndrome Type 1

    The risks of long-term steroid treatment include weight gain, elevated blood sugar, thinning of the bones, poor wound healing, difficulty in fighting infections, mood swings[empowher.com] Though most episodes of cytopenias respond to courses of conventional immunomodulatory agents, some ALPS patients, especially those with massive splenomegaly and hypersplenism[doi.org] People taking steroids may gain weight quickly. Some parents talk to teachers about the side effects of steroids in advance, so that classmates know what to expect.[daviddarling.info]

    Missing: Small Testicular Volume
  • Liver Cirrhosis

    As the disease gets worse, symptoms may include: Loss of appetite Lack of energy (fatigue) Weight loss or sudden weight gain Bruises Yellowing of skin or the whites of eyes[my.clevelandclinic.org] We performed LS in 83 patients with massive splenomegaly ( 30 cm) secondary to portal hypertension and liver cirrhosis.[ncbi.nlm.nih.gov] gain, so it’s not surprising that they’ve also been linked to liver damage.[health.com]

    Missing: Small Testicular Volume
  • Klinefelter Syndrome

    gain, especially on the stomach or trunk tiredness and fatigue small penis disproportionately long arms and legs compared to the length of the body taller than average height[betterhealth.vic.gov.au] They concluded that the decline in serum testosterone may be related to the small testicular volume and Leydig cell loss near the scars after the procedures.[web.archive.org] The treatment of men with Klinefelter syndrome has been thought to be limited by the small testicular volume, extensive tubular sclerosis, and high FSH typically found for[dx.doi.org]

    Missing: Massive Splenomegaly
  • Non-Hodgkin Lymphoma

    The weight of scientific evidence in policy and law. Am J Public Health 95:S129-S136 16030328.[doi.org] […] antibiotic therapy may result in remission of the disease.[ 97 ] Splenic marginal zone lymphoma Splenic marginal zone lymphoma is an indolent lymphoma that is marked by massive[web.archive.org] […] antibiotic therapy may result in remission of the disease.[ 108 ] Splenic marginal zone lymphoma Splenic marginal zone lymphoma is an indolent lymphoma that is marked by massive[cancer.gov]

    Missing: Small Testicular Volume
  • Overeating

    Weight Gain Unhealthy weight gain is one of the biggest dangers associated with eating too much.[healthyeating.sfgate.com] Overeating is the excess food consumed in relation to the energy that an organism expends (or expels via excretion), leading to weight gaining and often obesity.[en.wikipedia.org] Why that was so wasn’t clear, but Somers theorizes that it was because the participants were gaining weight, and therefore fat, during the study.[healthland.time.com]

    Missing: Massive Splenomegaly Small Testicular Volume
  • Leukemia

    Targeted Therapy Side effects may include swelling, bloating, sudden weight gain, anemia, nausea, vomiting, diarrhea, muscle craps or rashes.[cancersupportcommunity.org] Splenomegaly can be massive, consistency high, with the fibrous thickening of the capsule.[ncbi.nlm.nih.gov] Nausea, vomiting, weight gain and muscle cramps were more frequent with high-dose Gleevec.[web.archive.org]

    Missing: Small Testicular Volume
  • Gaucher Disease

    This case was a girl diagnosed with type 2 Gaucher disease at 12months of age who presented with poor weight gain from infancy, stridor, hypertonia, hepatosplenomegaly, trismus[ncbi.nlm.nih.gov] CONCLUSION: HALS for GD patients with refractory hypersplenism and massive splenomegaly is safe and feasible in experienced hands.[ncbi.nlm.nih.gov] The therapy is well tolerated, with side effects usually being both rare andmild. 8 Local reactions can occur, and ERT may be associated with inadequate weight gain in some[haematologica.org]

    Missing: Small Testicular Volume
  • Primary Myelofibrosis

    The patients in the ruxolitinib group had a mean gain in body weight of 4.43 kg by week 48, whereas the mean body-weight gain in the best-available-therapy group was minimal[doi.org] She also underwent splenectomy when she was 13 years old, due to massive splenomegaly, anemia and various infection disease episodes.[ncbi.nlm.nih.gov] Primary myelofibrosis (PMF) is a chronic myeloproliferative neoplasm characterized by progressive anemia, massive splenomegaly, leukoerythroblastosis, extramedullary hematopoiesis[ncbi.nlm.nih.gov]

    Missing: Small Testicular Volume

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