May Be Progressive: Causes & Reasons

Possible Causes for May Be Progressive

In other cases, symptoms may stop progressing entirely. Treatment and lifestyle changes can help slow the progression of focal dystonia. [medicalnewstoday.com]

At first, the dystonia may affect only the trunk or leg but often progresses to affect the whole body, usually moving cephalad. [msdmanuals.com]

Excessive muscle spasms may progress proximally, leading to abduction of the arm. [patient.info]

Neonatal Adrenoleukodystrophy

Symptoms may include progressive stiffness, weakness, or paralysis of the lower limbs and loss of coordination. Brain function deterioration may also been seen. [medical-dictionary.thefreedictionary.com]

Although adult-onset ALD generally progresses more slowly than the childhood form, it may also cause brain function to progressively deteriorate. [simplygoodnaturalfoods.com]

The childhood form may be chronic and treatable for a few years with a special diet. ALD was formerly classified under Schilder's disease. [medical-dictionary.thefreedictionary.com]

Keratoconus

Keratoconus may progress for 10-20 years and then slow in its progression. Each eye may be affected differently. [aoa.org]

Keratoconus may progress to acute corneal hydrops even after cross-linking. In some cases, keratoconus progresses during pregnancy. [ncbi.nlm.nih.gov]

As keratoconus progresses, the cornea bulges more and vision may become more distorted. [aoa.org]

Primary Progressive Multiple Sclerosis

This trial shows that the anti-CD20 antibody ocrelizumab may reduce disability progression in adults younger than 55 years old with primary progressive MS. [dynamed.com]

We concluded that physical disability in PPMS is not directly related to brain atrophy and that focal inflammatory white matter lesions may contribute to progressive neuronal [ncbi.nlm.nih.gov]

The rate of progression may vary with occasional plateaus and temporary minor improvements, but declining neurologic progression is continuous. [columbianeurology.org]

Muscular Dystrophy

For example, patients may have progressive difficulty lifting or climbing stairs. In some forms of LGMD, the heart muscle is also affected. [kennedykrieger.org]

Some cases may be mild and progress very slowly over a normal lifespan, while others produce severe muscle weakness, functional disability, and loss of the ability to walk [ninds.nih.gov]

Some symptoms can be treated, and progression may be slowed with medications. [cedars-sinai.edu]

Pseudo-Hurler Polydystrophy

Specific symptoms and rate of progression may vary from case to case although the disorder is often slowly progressive. [rarediseases.org]

These symptoms may progress to cause difficulty with specific tasks (e.g., getting dressed). Eventually, carpal tunnel syndrome may develop. [rarediseases.org]

Progressive degeneration of the hip and joint contractures may cause difficulty walking or force affected individuals to walk with a characteristic waddling gait. [rarediseases.org]

Singh-Chhaparwal-Dhanda Syndrome

Other ominous signs — such as complete paralysis, decerebrate posture, a positive Babinski's reflex, and small, reactive pupils — may rapidly progress to death. * Posterior [checkorphan.org]

The most promising treatments will progress to Phase 3 studies. [rarediseases.info.nih.gov]

These signs may be preceded by characteristic signs and symptoms, such as a headache, vomiting, drowsiness, confusion, unequal pupils, dysphagia, cranial nerve palsies, a [checkorphan.org]

Congenital Disorder of Glycosylation Type 1X

Morbidity in these infants includes infection, seizure, and hypoalbuminemia with third spacing that may progress to anasarca. [medilib.ir]

Infants with CDG may present with fulminant multi-organ disease, intractable seizures, or severe hypoalbuminemia progressing to anasarca. [atm.amegroups.com]

Infants and children with CDG do not typically have the progressive hepatosplenomegaly and dysostosis multiplex often seen in lysosomal storage diseases. [medilib.ir]

Collagenopathy Type 2 - Collagenopathy Type 11

Otolaryngologic Features Hearing loss may also occur in Stickler syndrome and may be progressive. [rarediseases.org]

Progressive kyphoscoliosis may result in cord compression with upper motor neuron signs and bladder or bowel dysfunction. [gimjournal.org]

Spinal abnormalities associated with Stickler may become progressively worse and may be associated with back pain. [rarediseases.org]

Joubert Syndrome Type 5

Another aspect that may determine progressivity is the association with a liver disease, and particularly a liver fibrosis that may need liver transplantation. [orpha.net]

Therefore, JS is considered a multisystem disorder, and several of the additional features may be progressive. [rarediseases.org]

This allows prompt symptomatic treatments to be set up which may delay the progression towards end-stage renal failure and prevent the development of complications, such as [jmg.bmj.com]

Ureteral Lymphoma

Follicular lymphoma is a form of low-grade lymphoma, implying that the tumors are typically slow-growing and that it may take a number of years for the disease to progress [ncbi.nlm.nih.gov]

However, a lymphoma of the ureter typically leads to ureteral obstruction, which may cause progressive deterioration of kidney function if left untreated, as in the present [ncbi.nlm.nih.gov]

Papillary Conjunctivitis

In rare instances, this opacity is congenital.[4] In some, there is a family history of corneal growth disorders which may be progressive with age. [en.wikipedia.org]

Much more commonly, misuse of contact lenses may be a precipitating factor. [en.wikipedia.org]

Spastic Tetraplegia - Thin Corpus Callosum - Progressive Postnatal Microcephaly

[…] disorder due to serine deficiency characterized by neonatal to infantile onset of global developmental delay, postnatal microcephaly and intellectual disability, which may [orpha.net]

Homepage Rare diseases Search Search for a rare disease Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome Disease definition A rare neurometabolic [orpha.net]

[…] be associated with slowly progressive spastic tetraplegia mainly affecting the lower extremities, seizures, and brain MRI findings including thin corpus callosum, delayed [orpha.net]

Diphenylthiourea Allergic Contact Dermatitis

PMID: 18674454 Vesicular Contact Reaction May Progress into Erythema Multiforme. [pubmed.ncbi.nlm.nih.gov]

Pulmonary Hyalinizing Granuloma

[…] be progressive, but does not cause death Microscopic (histologic) description Central keloid-like collagen, arranged in whorls, surrounded by foreign body giant cells simulating [pathologyoutlines.com]

PHG are considered as a benign and slowly evolving disease, but associated mediastinal fibrosis may evolve on its own. Only steroid therapy may slow down progression. [infona.pl]

[…] nodular amyloidosis May have plasma cells and lymphocytes between collagenous bands Usually no epithelioid granulomas, no necrosis Back to top [pathologyoutlines.com]

Nephritic Syndrome

The syndrome can be Acute (serum creatinine rises over many weeks or less) Chronic (renal insufficiency may progress over years) Nephritic syndrome can also be Primary (idiopathic [msdmanuals.com]

GN may be restricted to the kidney (primary glomerulonephritis) or be a secondary to a systemic disease (secondary glomerulonephritis). [ncbi.nlm.nih.gov]

Rapidly progressive glomerulonephritis (RPGN) is an acute glomerulonephritis resulting from the secondary sequelae of inflammatory (crescenteric) glomerulonephritis, of which [msdmanuals.com]

Maturity-Onset Diabetes of the Young Type 4

People with HNF4-alpha are generally treated with a sulphonylurea tablet but may progress on to needing insulin. HNF1-beta. [diabetes.org.uk]

They may also have had a low blood sugar at, or soon after, birth which might have needed treatment. [diabetes.org.uk]

Adenomyoepithelial Breast Adenosis

[…] to malignancy may be associated with older age (> 50 years) and mass on imaging (Springerplus 2013;2:50) Case reports 17 year old girl with a palpable lump (Turk Patoloji [pathologyoutlines.com]

[…] microcalcifications Radiology images Images hosted on other servers: Left breast Hypoechoic mass Irregular spiculated dense mass Spiculated hypoechoic mass Prognostic factors Unknown but progression [pathologyoutlines.com]

Juvenile GM2-Gangliosidosis

Progressive proximal muscle wasting, leg weakness, and fasciculations may be noted. [emedicine.medscape.com]

(have) interfere(d) with disease progression Information from the National Library of Medicine To learn more about this study, you or your doctor may contact the study research [clinicaltrials.gov]

Type II usually progresses more slowly than type I, but still causes a shortened life expectancy. [medlineplus.gov]

Bilateral Optic Nerve Meningioma

[…] be spared initially, rapid progression to bilateral blindness is usual. [semanticscholar.org]

Survey of ophthalmology 1994 Malignant optic glioma is a distinct disease primarily affecting middle-aged adults, and the chiasm is always involved, and although one eye may [semanticscholar.org]

Blepharoconjunctivitis

In rare instances, this opacity is congenital.[4] In some, there is a family history of corneal growth disorders which may be progressive with age. [en.wikipedia.org]

Much more commonly, misuse of contact lenses may be a precipitating factor. [en.wikipedia.org]

Age-Related Macular Degeneration

Dietary supplements may help slow progression of the disorder. Eye injections and laser treatments may be necessary for some people. [msdmanuals.com]

Because Dry AMD can sometimes progress into Wet AMD, you may also find Wet AMD referred to as Late of Advanced AMD. [fightingblindness.ie]

In wet AMD, loss of vision tends to progress quickly, usually over days or weeks, and may be even more sudden if one of the abnormal blood vessels bleeds. [msdmanuals.com]

Maturity-Onset Diabetes of the Young Type 6

People with HNF4-alpha are generally treated with a sulphonylurea tablet but may progress on to needing insulin. HNF1-beta. [diabetes.org.uk]

They may also have had a low blood sugar at, or soon after, birth which might have needed treatment. [diabetes.org.uk]

Tarsal Synostosis

Osteoarthritis and rheumatoid arthritis, dislocation and history of fracture are factors which may lead to progressive loss of function and/ or surgical intervention TRAUMATISME [ucuyelelipimiky.ml]

Symptoms may include pain, swelling, deformity, and bruising. Common Bony and/ or Articular Conditions. [ucuyelelipimiky.ml]

Geotrichosis

This may progress to cavitation, usually with thin walls, and the overall pattern resembles tuberculosis. None of these imaging changes is diagnostic. [info.isradiology.org]

In many patients the chest radiograph will be normal, but some may show peribronchial thickening and a fine nodular mottling at the bases of the lungs. [info.isradiology.org]

Acute Retinal Necrosis

However, retinal detachment may still occur/progress even after laser. [eyewiki.aao.org]

ARN may be seen in AIDS patients also. Previous history of herpetic infection including encephalitis may be present. [eyewiki.aao.org]

Ultrawide field fundus photography (Optos) may document and help in monitoring the progression of the disease.[11][12] Ultrasonograms may be helpful to rule out retinal detachment [ncbi.nlm.nih.gov]

Chromophobe Renal Cell Carcinoma Classic Variant

[…] be associated with progression, recurrence free survival and overall survival (Sci Rep 2015;5:10328) Differential diagnosis Clear cell renal cell carcinoma (CCRCC): No koilocytic [pathologyoutlines.com]

[…] expression is suppressed in clear cell RCC) (Cancer Cell 2014;26:319) Sarcomatoid tumors have different genetic abnormalities (Mod Pathol 2007;20:303) MiRNA expression patterns may [pathologyoutlines.com]

Cone Dystrophy

[…] with low glycemic index foods, with reduced progression of advanced AMD,[3] and may therefore delay the progression of cone dystrophy. [en.wikipedia.org]

There may, however, be overlap as some forms of cone dysfunction syndrome, such as achromatopsia,4 6 7 are associated with limited progression over time in a minority of subjects [bjo.bmj.com]

As the condition progresses, individuals may develop involuntary eye movements (nystagmus). [medlineplus.gov]

Ovarian Low Malignant Potential Tumor

Mucinous borderline ovarian tumors with BRAFV600E mutation may have low risk for progression to invasive carcinomas. [scielo.org.mx]

Achromatopsia Type 4

Although the fundus is usually normal, macular changes (which may show early signs of progression) and vessel narrowing may be present in some affected individuals. [ncbi.nlm.nih.gov]

Nystagmus and photophobia, marked in infancy, may improve with age. Achromatopsia is a non-progressive disorder, which means the vision is usually stable over time. [aapos.org]

Visual acuity is usually stable over time; both nystagmus and sensitivity to bright light may improve slightly. [ncbi.nlm.nih.gov]