May Be Progressive: Causes & Reasons

Possible Causes for May Be Progressive

In other cases, symptoms may stop progressing entirely. Treatment and lifestyle changes can help slow the progression of focal dystonia. [medicalnewstoday.com]

At first, the dystonia may affect only the trunk or leg but often progresses to affect the whole body, usually moving cephalad. [msdmanuals.com]

Excessive muscle spasms may progress proximally, leading to abduction of the arm. [patient.info]

Neonatal Adrenoleukodystrophy

Hepatomegaly may be present. Progressive sensorineural hearing deficit and visual disturbances develop during the first years of life. [link.springer.com]

Symptoms may include progressive stiffness, weakness, or paralysis of the lower limbs and loss of coordination. Brain function deterioration may also been seen. [medical-dictionary.thefreedictionary.com]

Although adult-onset ALD generally progresses more slowly than the childhood form, it may also cause brain function to progressively deteriorate. [healthinhandorganics.com]

Primary Progressive Multiple Sclerosis

This trial shows that the anti-CD20 antibody ocrelizumab may reduce disability progression in adults younger than 55 years old with primary progressive MS. [dynamed.com]

We concluded that physical disability in PPMS is not directly related to brain atrophy and that focal inflammatory white matter lesions may contribute to progressive neuronal [ncbi.nlm.nih.gov]

The rate of progression may vary with occasional plateaus and temporary minor improvements, but declining neurologic progression is continuous. [columbianeurology.org]

Keratoconus

Keratoconus may progress for 10-20 years and then slow in its progression. Each eye may be affected differently. [aoa.org]

Keratoconus may progress for 10-20 years and then slow or stabilize. Each eye may be affected differently. Learn more about keratoconus symptoms. [nkcf.org]

As keratoconus progresses, the cornea bulges more and vision may become more distorted. [aoa.org]

Drug or Radiation Exposure-Related Interstitial Lung Disease

Some treatments may improve symptoms temporarily or slow disease progress. [kristv.com]

The course is variable and may either spontaneously remit or progress. [emedicine.medscape.com]

[…] fibrotic NSIP may be stable with residual disease, or may be progressive irreversible disease with potential for some stabilisation IPF progressive irreversible disease despite [quartz.tg.com.au]

Retinal Macular Dystrophy Type 2

The disease may progress slowly or rapidly. Dry macular degeneration may advance and cause vision loss with or without turning into the wet type of the disease. [brightfocus.org]

Although there is no cure for macular degeneration, early detection and treatment may slow progression of the disease. [pgheyemds.com]

As MacTel progresses, it may encompass an oval region with a radius of about 6⁰ horizontally and 5⁰ vertically, centered on the foveola. [lmri.net]

Muscular Dystrophy

Some cases may be mild and progress very slowly over a normal lifespan, while others produce severe muscle weakness, functional disability, and loss of the ability to walk [ninds.nih.gov]

For example, patients may have progressive difficulty lifting or climbing stairs. In some forms of LGMD, the heart muscle is also affected. [kennedykrieger.org]

Some symptoms can be treated, and progression may be slowed with medications. [cedars-sinai.edu]

Progressive Bulbar Paralysis

The voice usually sounds nasal but may be hoarse. As symptoms progress, people may be unable to control emotional responses and may laugh or cry inappropriately. [merck.com]

Common symptoms reported by people with progressive bulbar palsy Reports may be affected by other conditions and/or medication side effects. [patientslikeme.com]

Emotions may be changeable: People with progressive pseudobulbar palsy may switch from happiness to sadness quickly and without reason. [merck.com]

Secondary Syphilis of Vulva

If you aren’t treated for secondary syphilis, the disease will likely progress to the latent stage, and may even progress to the tertiary stage. [healthline.com]

Latent Syphilis If you’re not treated for secondary syphilis, the disease may progress to the latent (hidden) phase. [webmd.com]

Latency can last 3–30 years and may or may not progress to the final, or tertiary, syphilis. About 30 percent of infected people persist in a latent state. [healthcommunities.com]

Late-Onset Pompe Disease

The second form is a late onset type, and it may begin any time from one year of age to adulthood [late onset Pompe disease (LOPD)] with a chronic course that may progress [ncbi.nlm.nih.gov]

Patients may develop a waddling or swaying gait, and may find it difficult to stand after sitting, running, or climbing stairs. [pompediseasenews.com]

[…] be a marker of renal compensation for chronic carbon dioxide retention.87 Chronic respiratory insufficiency may progress to development of cor pulmonale if left untreated [ncbi.nlm.nih.gov]

Erb Muscular Dystrophy

Breathing difficulties may become progressively worse in such cases. [rarediseases.org]

Some cases may be mild and progress very slowly over a normal lifespan, while others produce severe muscle weakness, functional disability, and loss of the ability to walk [ninds.nih.gov]

In most cases, the arms, legs, and spine become progressively deformed, and there may be some cognitive impairment. [webmd.com]

Upper Motor Neuron Disease

PLS and PMA are considered variants of ALS, and people with these disorders may progress to develop true ALS. [neurology.emory.edu]

Dysarthria Progressive bulbar palsy may manifest as progressive disturbance of speech lead in to dysarthria .[2]. [explainmedicine.com]

It may slow the progression and extend life by 2-3 months. [can.ubc.ca]

Limb-Girdle Muscular Dystrophy Type 1F

Breathing difficulties may become progressively worse in such cases. [rarediseases.org]

May have normal CK. May have distal muscle weakness. LGMD 1B (lamin A/C) Childhood May have neonatal hypotonia. There is usually slow progression. [patient.info]

The calf muscles may be relatively large. Weakness is progressive. By the age of 12, most patients are unable to walk and need to use a wheelchair. [brainfoundation.org.au]

Pseudo-Hurler Polydystrophy

The symptoms of this disorder are similar, but less severe than those of I-cell disease (mucolipidosis type II) and may include progressive joint stiffness, curvature of the [informationtherapy.in]

Specific symptoms and rate of progression may vary from case to case although the disorder is often slowly progressive. [rarediseases.org]

These symptoms may progress to cause difficulty with specific tasks (e.g., getting dressed). Eventually, carpal tunnel syndrome may develop. [rarediseases.org]

Progressive Osseous Heteroplasia

Progressive osseous heteroplasia (OMIM 166350) is a rare autosomal dominant condition that presents in childhood as dermal ossification and may progress deeper to involve [ncbi.nlm.nih.gov]

In some individuals, it may progress extremely slowly; in others it may progress more rapidly. Most individuals experience a gradual progression of the condition. [rareguru.com]

These areas may become progressively widespread and may grow together (coalesce) to form even larger areas of hardened and thickened skin (dermal ossification). [rarediseases.org]

Lower Motor Neuron Syndrome with Late-Adult Onset

Dysarthria Progressive bulbar palsy may manifest as progressive disturbance of speech lead in to dysarthria .[2]. [explainmedicine.com]

[…] require bracing or surgery 18 months+ (juvenile-onset) Highest motor milestone achieved ABLE TO WALK INDEPENDENTLY (“walkers,” although they may progressively lose this ability [togetherinsma.com]

Limb weakness may also become more evident as the disease progresses, with both upper and lower motor neuron signs. [verywell.com]

Amyotrophic Lateral Sclerosis Type 1

The voice usually sounds nasal but may be hoarse. As symptoms progress, people may be unable to control emotional responses and may laugh or cry inappropriately. [msdmanuals.com]

However, preclinical models indicate that cannabinoids may hold the potential to delay ALS progression, lending support to anecdotal reports by some patients that cannabinoids [norml.org]

Progression varies between individuals. In the early stages, signs and symptoms may be barely noticeable, but the weakness becomes more visible over time. [medicalnewstoday.com]

Localized Anterior Staphyloma

There may be associated secondary angle closure glaucoma, may cause progression of the bulge if not treated. Defective vision occurs due to marked corneal astigmatism. [scientiait.com]

Papillary Conjunctivitis

In rare instances, this opacity is congenital.[4] In some, there is a family history of corneal growth disorders which may be progressive with age. [en.wikipedia.org]

Much more commonly, misuse of contact lenses may be a precipitating factor. [en.wikipedia.org]

Spastic Tetraplegia - Thin Corpus Callosum - Progressive Postnatal Microcephaly

[…] disorder due to serine deficiency characterized by neonatal to infantile onset of global developmental delay, postnatal microcephaly and intellectual disability, which may [orpha.net]

Homepage Rare diseases Search Search for a rare disease Spastic tetraplegia-thin corpus callosum-progressive postnatal microcephaly syndrome Disease definition A rare neurometabolic [orpha.net]

[…] be associated with slowly progressive spastic tetraplegia mainly affecting the lower extremities, seizures, and brain MRI findings including thin corpus callosum, delayed [orpha.net]

Visual Pathway Glioma

The chiasm is always involved, and although one eye may be spared initially, rapid progression to bilateral blindness is usual. The disease is uniformly fatal. [pubmed.ncbi.nlm.nih.gov]

Nephritic Syndrome

The syndrome can be Acute (serum creatinine rises over many weeks or less) Chronic (renal insufficiency may progress over years) Nephritic syndrome can also be Primary (idiopathic [msdmanuals.com]

GN may be restricted to the kidney (primary glomerulonephritis) or be a secondary to a systemic disease (secondary glomerulonephritis). [ncbi.nlm.nih.gov]

Rapidly progressive glomerulonephritis (RPGN) is an acute glomerulonephritis resulting from the secondary sequelae of inflammatory (crescenteric) glomerulonephritis, of which [msdmanuals.com]

Diphenylthiourea Allergic Contact Dermatitis

PMID: 18674454 Vesicular Contact Reaction May Progress into Erythema Multiforme. [pubmed.ncbi.nlm.nih.gov]

Blepharoconjunctivitis

In rare instances, this opacity is congenital.[4] In some, there is a family history of corneal growth disorders which may be progressive with age. [en.wikipedia.org]

Much more commonly, misuse of contact lenses may be a precipitating factor. [en.wikipedia.org]

Age-Related Macular Degeneration

Dietary supplements may help slow progression of the disorder. Eye injections and laser treatments may be necessary for some people. [msdmanuals.com]

Because Dry AMD can sometimes progress into Wet AMD, you may also find Wet AMD referred to as Late of Advanced AMD. [fightingblindness.ie]

In wet AMD, loss of vision tends to progress quickly, usually over days or weeks, and may be even more sudden if one of the abnormal blood vessels bleeds. [msdmanuals.com]

Adenomyoepithelial Breast Adenosis

[…] to malignancy may be associated with older age (> 50 years) and mass on imaging (Springerplus 2013;2:50) Case reports 17 year old girl with a palpable lump (Turk Patoloji [pathologyoutlines.com]

[…] microcalcifications Radiology images Images hosted on other servers: Left breast Hypoechoic mass Irregular spiculated dense mass Spiculated hypoechoic mass Prognostic factors Unknown but progression [pathologyoutlines.com]

Maturity-Onset Diabetes of the Young Type 6

People with HNF4-alpha are generally treated with a sulphonylurea tablet but may progress on to needing insulin. HNF1-beta. [diabetes.org.uk]

They may also have had a low blood sugar at, or soon after, birth which might have needed treatment. [diabetes.org.uk]

Maturity-Onset Diabetes of the Young Type 4

People with HNF4-alpha are generally treated with a sulphonylurea tablet but may progress on to needing insulin. HNF1-beta. [diabetes.org.uk]

They may also have had a low blood sugar at, or soon after, birth which might have needed treatment. [diabetes.org.uk]

Bilateral Optic Nerve Meningioma

[…] be spared initially, rapid progression to bilateral blindness is usual. [semanticscholar.org]

Survey of ophthalmology 1994 Malignant optic glioma is a distinct disease primarily affecting middle-aged adults, and the chiasm is always involved, and although one eye may [semanticscholar.org]

Classic Progressive Supranuclear Palsy Syndrome

Key points • Ophthalmoparesis, especially downgaze impairment, is a classic clinical feature of progressive supranuclear palsy that may appear later in the course of the disorder [medlink.com]

Progression All the symptoms of PSP and CBD get worse as the diseases progress. Eventually, people may become completely bedbound and unable to safely walk. [brain.northwestern.edu]

As the disease progresses, the predominant feature may change, with patients moving from a parkinsonism to a cerebellar ataxia defined disease. [lecturio.com]