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26 Possible Causes for Mean Corpuscular Volume Decreased, Microcytic Anemia, Plummer-Vinson Syndrome

  • Plummer-Vinson Syndrome

    Investigations Complete blood cell (CBC) counts: decreased values of hemoglobin, hematocrit, mean corpuscular volume Peripheral blood smears: hypochromic microcytic anemia[slideshare.net] The authors report the case of a 6 year old with Plummer-Vinson syndrome.[ncbi.nlm.nih.gov] Blood tests demonstrate a hypochromic microcytic anemia that is consistent with an iron-deficiency anemia.[en.wikipedia.org]

  • Iron Deficiency Anemia

    IV iron sucrose resulted in a statistically significant and clinically meaningful increase in hemoglobin, mean corpuscular volume, serum iron, ferritin, and % iron saturation[ncbi.nlm.nih.gov] The most used name is Plummer-Vinson syndrome, named after Henry Stanley Plummer (1874–1936) and Porter Paisley Vinson (1890–1959) who were physicians on the staff of the[dx.doi.org] Abstract Iron-refractory iron deficiency anemia (IRIDA) is a rare autosomal recessive disease characterized by congenital hypochromic microcytic anemia, low transferrin saturation[ncbi.nlm.nih.gov]

  • Iron Deficiency

    Average size of RBCs (mean corpuscular volume, MCV)—decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean[labtestsonline.org] Symptoms of iron deficiency include: fatigue dizziness/lightheadedness pallor hair loss twitches irritability weakness pica brittle or grooved nails hair thinning PlummerVinson[en.wikipedia.org] Differentiation from other microcytic anemias Iron deficiency anemia must be differentiated from other microcytic anemias (see table Differential Diagnosis of Microcytic Anemia[merckmanuals.com]

  • Gastrointestinal Hemorrhage

    Physical signs could indicate presence of an underlying condition such as celiac disease, inflammatory bowel disease, Plummer-Vinson syndrome, and Peutz-Jeghers syndrome[[doi.org] anemia, chronic blood loss Protect airway and give high-flow oxygenInsert 2 large-bore (14-16G) IV cannulate take blood for FBC, U&E, LFT, clotting, cross-match 4-6 units[slideshare.net] Microcytic red blood cells or iron deficiency anemia suggests chronic bleeding.[doi.org]

  • Anemia of Chronic Disease

    Range 80 - 97 Mean corpuscular volume is decreased in anemia of chronic disease.[chronicillnessrecovery.org] Rare symptoms & signs: -Glossitis or angular cheilitis -Dysphagia due to esophageal web (Plummer-Vinson syndrome) -Koilonychia; "Spoon" fingernails -Pica -soreness of mouth[quizlet.com] Conclusions: CD should be included in the differential diagnosis of microcytic anemia.[doi.org]

  • Microcytosis

    Abstract Twenty-three hemodialysis patients exposed to an accidental aluminum overload, showed increased erythropoietin requirements and decreased erythrocyte mean corpuscular[ncbi.nlm.nih.gov] […] is plummer-vinson syndrome?[quizlet.com] Anemia need not be present. If there is an anemia, the anatomical diagnosis is “microcytic anemia”; otherwise, it is “a microcytic red cell picture.” ...[link.springer.com]

  • Achlorhydria

    LABORATORY TESTS Laboratory examinations typically reveal iron deficiency anemia (hypochromic microcytic) with decreased values of hemoglobin, hematocrit, mean corpuscular[flipper.diff.org] It has been reported a frequent finding in microcytic anemia, 1, 2 hyperthyroidism 3 and chronic arthritis. 4 For many years dilute hydrochloric acid has been employed in[nejm.org] It has been reported a frequent finding in microcytic anemia, 1 , 2 hyperthyroidism 3 and chronic arthritis. 4 For many years dilute hydrochloric acid has been employed in[nejm.org]

  • Macrocytic Anemia

    Mean corpuscular volume Mean corpuscular volume is the average volume of red blood cells and is reflective of RBC size .[lecturio.com] RESULTS: In part A, ABG was detected in 37.5% of patients with macrocytic and in 19.5% of those with microcytic anemia.[ncbi.nlm.nih.gov] Average size of RBCs (mean corpuscular volume, MCV)—decreased Average amount of hemoglobin in RBCs (mean corpuscular hemoglobin, MCH)—decreased Hemoglobin concentration (mean[labtestsonline.org]

  • Hereditary Sideroblastic Anemia

    Eleven weeks later, the patient's hemoglobin level and mean corpuscular volume had decreased to 9.8 g per deciliter (6.1 mmol per liter) and 59 micrometers 3 , respectively[nejm.org] Iron-deficiency anemia PlummerVinson syndrome Macro-: Identification of a human mitochondrial ABC transporter, the functional orthologue of yeast Atm1p.[pdfoftheworld.us] Hypochromic microcytic anemias include: Iron deficiency anemia: The most common cause of microcytic anemia is an iron deficiency in the blood.[healthline.com]

  • Constitutional Megaloblastic Anemia due to Folate Metabolism Disorder

    Blood findings [ edit ] The blood film can point towards vitamin deficiency: Decreased red blood cell (RBC) count and hemoglobin levels [5] Increased mean corpuscular volume[en.wikipedia.org] […] of neuroepithelial tissue Pineoblastoma Pineocytoma Plaque-form urticaria pigmentosa Plasma cell tumor Plasmacytoma Pleomorphic liposarcoma Pleomorphic rhabdomyosarcoma Plummer-Vinson[se-atlas.de] […] by severe microcytic anemia, B-cell lymphopenia, panhypogammaglobulinemia, and variable neurodegeneration.[bloodgenetics.com]

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