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111 Possible Causes for Mean Corpuscular Volume Increased, Reticulocytes Increased

  • Leukoerythroblastic Anemia

    An increased absolute number of reticulocytes indicates increased marrow erythropoiesis. u. Rouleaux: red cells in stacks, as coins.[kerrybrandis.com] mean corpuscular volume (macrocytic anemia: MCV 100 fL) Ethanol abuse Folate deficiency Vitamin B12 deficiency Myelodysplastic syndromes Acute myeloid leukemias (eg, erythroleukemia[timeofcare.com] […] granulocytes from marginal pools PBS- normocytic normochromic initially, polychromasia 5-7 days Reticulocyte count- increased (10-15%) after 5-7 days Platelets- increased[quizlet.com]

  • Congenital Dyserythropoietic Anemia

    On this treatment, hemoglobin and reticulocytes increased and transfusions became unnecessary.[ncbi.nlm.nih.gov] The reticulocyte count was always low, in spite of the increased erythropoietic activity. A beta-thalassemia trait inherited from the mother was demonstrated.[ncbi.nlm.nih.gov] , a moderate increase in unglycosylated (indirect) bilirubin, a low haptoglobin, and a gradual increase in ferritin level.[accessmedicine.mhmedical.com]

  • Autoimmune Hemolytic Anemia

    Over the course of the next 5 days, the Hb and Hct decreased to 4.1 g/dL and 12%, respectively, direct bili increased to 12.3 mg/day, reticulocytes slightly increased to 0.9%[ncbi.nlm.nih.gov] Reticulocyte counts are usually elevated, and an increased MCV (mean corpuscular volume) (greater than 100 fl) can be seen, due to the larger size of reticulocytes in comparison[cancertherapyadvisor.com] Laboratory data showed low hemoglobin levels and slightly increased reticulocyte counts, while direct and indirect antiglobulin tests were positive.[ncbi.nlm.nih.gov]

  • Paroxysmal Cold Hemoglobinuria

    […] count – usually elevated Positive indicators of hemolysis – hyperbilirubinemia, increased lactate dehydrogenase Direct Coombs Establish presence of immunoglobins and complement[arupconsult.com] In cold agglutinin disease, RBCs clump on the peripheral smear, and automated cell counts often reveal an increased mean corpuscular volume and spuriously low hemoglobin due[msdmanuals.com] Normal reticulocyte percentage is 0.5 to 1.5% b.[errolozdalga.com]

  • Bone Metastasis

    Bone metastases, or osseous metastatic disease, is a category of cancer metastases that results from primary tumor invasion to bone. Bone-originating primary tumors such as osteosarcoma, chondrosarcoma, and Ewing's sarcoma are rare. Unlike hematological malignancies that originate in the blood and form non-solid[…][en.wikipedia.org]

  • Cold Agglutinin Disease

    Typical bloodwork results would show: decreased hemoglobin (due to the red cell lysis) increased reticulocyte count (reflecting the marrow kicking red cell production into[transfusion.ca] The mean corpuscular volume (MCV) is elevated because of reticulocytosis, as well as agglutination of the RBCs.[web.archive.org] […] breakdown Indirect/ unconjugated bilirubin Reticulocytes : loss of erythrocytes reactive increase in erythropoiesis increase in reticulocytes in the peripheral blood In extreme[amboss.com]

  • Primary Myelofibrosis

    The percentage of reticulocytes is mildly increased but may vary widely in a given case.[patient-help.com]

  • Congenital Hemolytic Anemia

    After partial splenectomy, children overall had decreased transfusion requirements, increased hematocrits, decreased bilirubin levels, decreased reticulocyte counts, and elimination[ncbi.nlm.nih.gov] Mean corpuscular hemoglobin concentration (MCHC) is increased (35-38%) in approximately 50% of patients.[clinicaladvisor.com] As a result of splenectomy, reticulocyte counts often increase and transfusion needs are reduced.[orpha.net]

  • Paroxysmal Nocturnal Hemoglobinuria

    Erythrocytes fractionated by centrifugation revealed increased glycolytic enzyme activities of hexokinase, G3PD, PGK, TPI, PK, LDH, G6PD, and 6PGD in the reticulocyte-rich[pediatrics.aappublications.org] Blockade of terminal complement components presumably prolongs the survival of type III erythrocytes (since there was no simultaneous increase in reticulocytes), which are[nejm.org] The reticulocyte count often remains elevated because most PNH patients on eculizumab continue to have some extravascular hemolysis.[bloodjournal.org]

  • Fetal Erythroblastosis

    He or she will be anemic, with increased reticulocyte count, anisocytosis, spherocytosis, and young (nucleated, immature) red blood cells released into circulation.[symptoma.com] Peripheral blood morphology shows increased reticulocytes. Erythroblasts (also known as nucleated red blood cells) occur in moderate and severe disease.[moondragon.org] reticulocytes.[en.wikipedia.org]

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