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208 Possible Causes for Mediastinal Mass, T-Cell Leukemia

  • T-Cell Lymphoblastic Lymphoma

    A case of T-cell lymphoblastic lymphoma is described in which the patient presented with a characteristic mediastinal mass and lack of bone marrow involvement.[ncbi.nlm.nih.gov] Transplantation of whole bone marrow cells that express oncogenic K-Ras into wild-type recipient mice resulted in a highly penetrant, aggressive T-cell leukemia/lymphoma.[ncbi.nlm.nih.gov] This report describes a case of post-transplantation lymphoma presenting with a mediastinal mass causing superior vena cava syndrome, tracheal obstruction, and pleural effusion[ncbi.nlm.nih.gov]

  • T-Cell Acute Lymphoblastic Leukemia

    Computed tomography scan of the chest showed a large left mediastinal mass (9 7.2 7 cm) and left pleural effusion.[ncbi.nlm.nih.gov] This report suggests that a subset of CD7 T-cell leukemias without mature T-cell antigens (CD4-, CD8-) are minimally differentiated and can relapse as AML.[ncbi.nlm.nih.gov] Here, we describe a novel case of T-ALL associated with a mediastinal mass and a SET-NUP214 rearrangement, which was masked by a complex karyotype at the time of initial diagnosis[ncbi.nlm.nih.gov]

  • Non-Hodgkin Lymphoma

    The patient presented initially with persistent cough and an anterior mediastinal mass and had no bone marrow or CNS involvement at diagnosis.[ncbi.nlm.nih.gov] […] lymphoma, Hodgkin’s disease, Extranodal NK/T cell lymphoma, nasal type HTLV-1 (human T cell lymphotropic virus): Adult T cell leukemia or lymphoma HIV (human immunodeficiency[symptoma.com] Lymphoblastic lymphoma: high-grade lymphoma, which often manifests with a mediastinal mass, superior vena cava syndrome and meningeal disease with cranial nerve palsies.[patient.info]

  • Acute Lymphoblastic Leukemia

    Lastly, stridor is an alarming symptom that should indicate a possible mediastinal mass, which, in turn, may threaten the respiratory function.[symptoma.com] CONCLUSIONS: SLC7A7 plays a significant role in the pathogenesis of T-cell acute lymphoblastic leukemia. 2018 The Author(s). Published by S. Karger AG, Basel.[ncbi.nlm.nih.gov] A chest radiograph shows normal results with no mediastinal mass or pulmonary infiltrate.[pedsinreview.aappublications.org]

  • Childhood Acute Lymphoblastic Leukemia

    A chest radiography is needed in order to assess the presence of mediastinal masses.[symptoma.com] A plain chest radiograph should be obtained in all patients before any sedation or anesthesia to determine whether or not a mediastinal mass is present, which is more common[clinicaladvisor.com] The goal is to completely rid the body of leukemia cells that have not been found by common blood or marrow tests.[webmd.com]

  • Thyroid Lymphoma

    Good luck and keep us posted Cheers 21 yr old male (Our Son) Diffuse Large B-Cell Non Hodgkins Lymphoma Stage 1A Mediastinal Mass 8cm x 7cm Diagnosed October 09 Started course[cancerforums.net] Immunologic type of thyroid lymphoma in an adult T-cell leukemia endemic area in Japan. Leuk Lymphoma 1995; 17:341–344. PubMed Google Scholar 18.[link.springer.com]

  • Mediastinal Neoplasm

    The variation in these imaging findings played an important role in the differential diagnosis of this uncommon mediastinal mass.[ncbi.nlm.nih.gov] […] lymphoma/leukemia Hodgkin lymphoma Germ cell tumors Seminoma (Germinoma) Embryonal carcinoma Yolk sac tumor Teratoma Choriocarcinoma With associated somatic type malignancy[surgpathcriteria.stanford.edu] Others include extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma), other mature B-cell lymphomas, T-lymphoblastic lymphoma/leukemia, anaplastic[ncbi.nlm.nih.gov]

  • Thymoma

    We report a case of a 57-year-old male who presented an anterior mediastinal mass suspicious of thymoma by chest computed tomography.[ncbi.nlm.nih.gov] It is important to recognize normal thymocyte precursors by flow cytometry to differentiate them from T-cell lymphoblastic leukemia.[ncbi.nlm.nih.gov] Hematologic syndromes include red blood cell aplasia, erythrocytosis, pancytopenia, megakaryocytopenia, T-cell lymphocytosis, acute leukemia, and multiple myeloma.[emedicine.com]

  • Childhood Hodgkin's Disease

    A mediastinal mass greater than 1/3 the thoracic width was present in 19 children of whom 18 achieved remission and none relapsed.[ncbi.nlm.nih.gov] High survival rate with the LMT-89 regimen in lymphoblastic lymphoma (LL), but not in T-cell acute lymphoblastic leukemia (T-ALL).[myschedule.jp] The term "bulky disease" is used in cases where a mass larger than 6 cm is found, or in patients presenting with large mediastinal adenopathies.[symptoma.com]

  • Hodgkin's Disease

    A CT scan showed an ill-defined soft tissue mass anterior to and not well demarcated from the thyroid, and contiguous with a superior and anterior mediastinal mass.[ncbi.nlm.nih.gov] leukemia (t-AML); both entities are the result of the clonal selection of cells with accumulated genomic lesions induced by antineoplastic therapy.[ncbi.nlm.nih.gov] Non-Hodgkin lymphoma Hodgkin lymphoma Lymphomas Insight Blog 11/3/2017 Cancer Treatment: A Look at How It Has Evolved in 70 Years CAR T-Cell Therapy Immunotherapy Leukemias[dana-farber.org]

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