Medication Noncompliance & Pediatric Disorder: Causes & Reasons

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Medication Noncompliance, Pediatric Disorder,

Negated

None

Unsure

None

Possible Causes

Acne Vulgaris

TABLE 1 Patient demographics and disposition ENROLLED, N 97 COMPLETED STUDY, N 91 (4 noncompliant, 1 lost to follow-up, 1 protocol violation) MEAN AGE, YEARS 18.4 years (SD [ncbi.nlm.nih.gov]

Acne life cycle: the spectrum of pediatric disease. Semin Cutan Med Surg. 2011; 30 :S4–S6;S23. [ PubMed ] [ Google Scholar ] 18. [ncbi.nlm.nih.gov]

Rosenberg M, Waugh MS: Causes and consequences of oral contraceptive noncompliance. Am J Obstet Gynecol 1999; 180: 276–9. MEDLINE 5. [doi.org]

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Acute Gastroenteritis

Diet restrictions that prevent secondary malabsorption are extremely important; relapse typically occurs due to dietary noncompliance. [emedicine.medscape.com]

Seventy children with acute gastroenteritis and their parents completed the Rome III Diagnostic Questionnaire for Pediatric Functional GI Disorders and the Children's Somatization [ncbi.nlm.nih.gov]

Probiotics and prebiotics in pediatric diarrheal disorders. Expert Opin Pharmacother. 2013;14(4):397-409. (Review) Guarino A, Guandalini S, Lo Vecchio A. [ebmedicine.net]

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Vitamin D Deficiency

Two studies made specific reference to dropouts and sought to give some clarification about the reasons for dropout or noncompliance ( 15, 16 ), whereas 3 studies recorded [doi.org]

Hypocalcemic and hypercalcemic disorders in children. Current Problems in Pediatrics, Vol. 19, Issue. 10, p. 497. CrossRef Google Scholar Poskitt, E.M.E. 1988. [doi.org]

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Constipation

To avoid patient noncompliance due to the development of cramping and bloating that accompany changes in dietary fiber, fiber supplementation should be started at a low subtherapeutic [web.archive.org]

Mousa, The value of fluoroscopic defecography in the diagnostic and therapeutic management of defecation disorders in children, Pediatric Radiology, 45, 2, (173), (2015). [doi.org]

Long-term deterioration of quality of life in adult patients with celiac disease is associated with treatment noncompliance. Dig Liver Dis 2010;42(10):685–91. [worldgastroenterology.org]

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Anemia

noncompliance, cardiac ischemia, abnormal heart rhythms, kidney failure, pulmonary emboli, hypertension, and infections.[13] Treatment efforts are directed towards decreasing [en.wikipedia.org]

One of the most common pediatric disorders, anemia has many potential causes. Anemia is often a symptom of a disease rather than a disease itself. [childrenshospital.org]

IV) iron has a role in the treatment of IDA in pregnancy, particularly in women who present late, display severe anemia (Hb 9 g/dL), or risk factors, and are intolerant/noncompliant [hindawi.com]

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Urinary Tract Infection

Exceptions include women with an active vaginal infection and those who would be noncompliant with follow-up. 4 Avoid using synthetic or biologic grafts in primary rectocele [choosingwisely.org]

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Food Allergy

The numbers of participants in each arm who were included in analysis, noncompliant, and lost to follow-up in each arm were also recorded. [doi.org]

BACKGROUND/AIMS: We evaluated our 16-year single-center experience of pediatric post-transplant lymphoproliferative disorder (PTLD) cases who underwent liver transplantation [ncbi.nlm.nih.gov]

Long-term deterioration of quality of life in adult patients with celiac disease is associated with treatment noncompliance. Dig Liver Dis 2010;42(10):685–91. [worldgastroenterology.org]

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Iron Deficiency Anemia

noncompliance, cardiac ischemia, abnormal heart rhythms, kidney failure, pulmonary emboli, hypertension, and infections.[13] Treatment efforts are directed towards decreasing [en.wikipedia.org]

Blood Disorders Center, an integrated pediatric hematology and oncology partnership between Dana-Farber Cancer Institute and Boston Children's Hospital. [childrenshospital.org]

Most merely are noncompliant with therapy. [emedicine.com]

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Lactose Intolerance

The most common cause of apparent ineffectiveness or resistance to treatment with oral levothyroxine (LT(4)) is the result of noncompliance, known as pseudomalabsorption. [ncbi.nlm.nih.gov]

Lactose Intolerance, in Pediatric Nutrition in Chronic Diseases and Developmental Disorders, 2nd ed. Walberg Ekvall S and Ekvall VK, eds. [labtestsonline.org]

PATIENTS: The replacement T4 dose has been analyzed, from 2009 to 2012, in 34 hypothyroid patients due to Hashimoto's thyroiditis and lactose intolerance and being noncompliant [ncbi.nlm.nih.gov]

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Adjustment Reaction of Adolescence

Exclusive bonus features include Diagnosaurus DDx, 200 pediatrics topics, and medical news feeds. Learn more. Citation Stephens, Mark B., et al., editors. [unboundmedicine.com]

Pediatric depressive disorders: management priorities in primary care. Curr Opin Pediatr. 2008;20(5):551–559. 10. Lieberman JA III. [aafp.org]

Does not represent normal bereavement Does not persist for more than an additional 6 months once the stressor or its consequences have terminated Pediatric Considerations [unboundmedicine.com]

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Viral Exanthem

Most cases result from either noncompliance with recommended immunizations or primary vaccination failure. [ahcmedia.com]

Hurwitz S: Clinical Pediatric Dermatology: A Textbook of Skin Disorders of Childhood and Adolescence, ed 2. Philadelphia, WB Saunders Company, 1993, p 130 7. [contemporarypediatrics.com]

The authors review the classic course of common pediatric diseases associated with rashes, including varicella-zoster virus, herpes simplex virus (HSV), roseola, and rubella [ahcmedia.com]

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Familial Adenomatous Polyposis

In addition, the longitudinal model assesses the simultaneous effects of treatment group, time, and noncompliance with the assigned therapy. [nejm.org]

Older paternal age and fresh gene mutation: data on additional disorders. J Pediatr. 1975 Jan. 86(1):84-8. [Medline]. Bisgaard ML, Fenger K, Bülow S, Niebuhr E, Mohr J. [emedicine.medscape.com]

[…] nervosa or bulimia. 21.Subjects who will be unavailable for the duration of the trial, deemed unable to comply with the requirements of the study protocol, likely to be noncompliant [clinicaltrialsregister.eu]

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Infantile Gastroenteritis

[…] nursing diagnosis maternal, nanda nursing diagnosis macular degeneration, nanda nursing diagnosis pain management, nanda nursing diagnosis nutrition, nanda nursing diagnosis noncompliance [bipboppingdays.blogspot.com]

Although dehydration technically refers to pure water loss and can be associated with euvolemic or even hypervolemic states in certain pediatric disorders, the term is used [emedicine.medscape.com]

This 1828 work built upon that of Bichat and Laennec, who provided the initial scientific basis of medicine, and classified pediatric disorders (including infectious diseases [nature.com]

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Klinefelter Syndrome

[…] careful follow up and suggests this modality of therapy may not be appropriate for a substantial number of hypogonadal patients, but this strategy warrants consideration in noncompliant [ncbi.nlm.nih.gov]

disorders, resulting in a rise in the diagnosis and early referral to the pediatric endocrinologist. [ncbi.nlm.nih.gov]

To reduce patient noncompliance by understanding the reasons maintaining the behavior Table III Guide for counseling clinicians and parents (modified from Ross, 2008). [dx.doi.org]

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Appendicitis

[…] and were noncompliant ( Fig 3, Table 7 ). [dx.doi.org]

[…] and pregnant patients to spare ionizing radiation Abdominal CT scan in adults or pediatric patients without a diagnostic US Differential PID, ovarian torsion, gyn disorders [step2.medbullets.com]

National estimates of hospital utilization by children with gastrointestinal disorders: analysis of the 1997 kids' inpatient database. J Pediatr 2004 ; 144 :589–594. [doi.org]

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Functional Encopresis

Coexisting behavior problems are a predictor of poor outcome in toilet-training protocols. 19 Disruptive behavior and childhood noncompliance across multiple settings (e.g [aafp.org]

[…] encountered by psychologists and other practitioners in child clinical and pediatric psychology settings. [books.google.com]

Functional Fecal Soiling Withaout Constipation, Organic Cause or Neuropsychiatric Disorders? J. Pediatr Gatroenterol Nutr 2006;43(2):205-8 21. [degruyter.com]

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Scarlet Fever

[…] date, although since 1985, many reports of penicillin tolerance have been made.[26] The reason for the failure of penicillin to treat S. pyogenes is most commonly patient noncompliance [en.wikipedia.org]

Group A Streptococcal Infections Are Associated With Increased Risk of Pediatric Neuropsychiatric Disorders: A Taiwanese Population-Based Cohort Study. [ncbi.nlm.nih.gov]

[…] autoimmune neuropsychiatric disorders associated with streptococcal (PANDAS) infections. [medicalnewstoday.com]

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Zinc Deficiency

[…] group, 20 in the placebo group) were planned to be included in this study in a random assignment, but 2 patients in the zinc group and 7 patients in the placebo group were noncompliant [tinnitusformula.com]

Anxiety in Children In our practice, in addition to zinc deficiency, we often see yeast issues and gut issues in our pediatric patients with general anxiety disorder. [mensahmedical.com]

/hyperactivity disorder EFA — essential fatty acids EPD — enzyme-potentiated desensitization IGg — immunoglobulin G LC — long chain PUFA — polyunsaturated fatty acids Accepted [doi.org]

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Atrial Septal Defect

It usually results from a failure to diagnose and treat AIH as an etiology of cirrhosis, inadequate response or intolerance to immunosuppressive therapy, or noncompliance [hindawi.com]

Alex Thompson, Dawn Hackman and Larry Burd, Mortality in Fetal Alcohol Spectrum Disorders, Open Journal of Pediatrics, 04, 01, (21), (2014). [doi.org]

Each year, we treat hundreds of children, adolescents and even adults with a wide variety of heart defects and disorders. [web.archive.org]

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Autism

Results: General linear model repeated measures showed significant effect for time treatment interaction on the irritability [ F (2, 88) 3.94, p 0.02] and hyperactivity/noncompliance [online.liebertpub.com]

In two, randomized, double-blind, placebo-controlled studies in pediatric patients aged 6-17 years with irritability associated with autistic disorder, 8 weeks of treatment [ncbi.nlm.nih.gov]

RESULTS: General linear model repeated measures showed significant effect for time treatment interaction on the irritability [F(2, 88) 3.94, p 0.02] and hyperactivity/noncompliance [ncbi.nlm.nih.gov]

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Diabetes Mellitus Type 1

When a patient with type 1 DM loses metabolic control (such as during infections or periods of noncompliance with therapy), symptoms of diabetic ketoacidosis occur. [medical-dictionary.thefreedictionary.com]

Disordered Eating Behaviors Among Turkish Adolescents with and without Type 1 Diabetes. [busbid.baskent.edu.tr]

Adult and pediatric endocrinologists, specialists in treating hormonal disorders and disorders of the endocrine system, manage patients with diabetes. [medicinenet.com]

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Subdural Hematoma

Past medical history was significant for Hepatitis C, IV drug abuse, and chronic lower extremity cellulitis. [hindawi.com]

Headache is the most common symptom of MTBI. 4 Possible causes include posttraumatic migraine, tension headache, exacerbation of a preexisting headache disorder, analgesic [doi.org]

The patient stated that she was noncompliant with her prenatal care and with the antibiotics prescribed to her when she signed out AMA approximately 6 weeks priorly. [hindawi.com]

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Rhabdomyosarcoma

Influence of Noncompliance With Radiation Therapy Protocol Guidelines and Operative Bed Recurrences for Children With Rhabdomyosarcoma and Microscopic Residual Disease: A [emedicine.medscape.com]

Dana-Farber/Boston Children's Children with rhabdomyosarcoma are treated through the Bone and Soft Tissue Tumors Program at Dana-Farber/Boston Children's Cancer and Blood Disorders [dana-farber.org]

Author information 1 Division of Pediatric Hematology-Oncology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, Tennessee. 2 Division of Pediatric [ncbi.nlm.nih.gov]

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Diabetic Ketotic Coma

growth hormone, catecholamine) results in hyperglycemia and ketonemia Most common in type I diabetes Precipitated by infections MI drugs (steroids, thiazide diuretics) noncompliance [medbullets.com]

You’ll benefit from unique, global perspectives on adult and pediatric endocrinology prepared by an international team of renowned authorities. [books.google.com]

Tagamet) Diazoxide (Hyperstat) Glucocorticoids Loop diuretics Olanzapine (Zyprexa) Phenytoin (Dilantin) Propranolol (Inderal) Thiazide diuretics Total parenteral nutrition Noncompliance [aafp.org]

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Adrenogenital Syndrome

Eur Radiol 2000;10:1165) Probably under reported due to difficulty in identifying adrenal rests Tumors more common in patients with congenital adrenal hyperplasia who are noncompliant [pathologyoutlines.com]

[Adrenogenital syndrome with electrolyte disorders (Debré-Fibiger syndrome)]. Arch Fr Pediatr. 1957;14(1):20-35. [unboundmedicine.com]

Miller WL (1997) The adrenal cortex and its disorders. In: Brook C, Clayton P, Brown R (eds) Brook's Clinical Pediatric Endocrinology. [link.springer.com]

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Hemophilia

However, no child was removed from the study for any level of noncompliance. [content.nejm.org]

John Akabutu Comprehensice Centre for Bleeding Disorders – Pediatric Division Stollery Children’s Hospital Clinic Director Dr. [hemophilia.ca]

Kulkarni Nurse coordinator Sue Ann Hawes Pediatric Bleeding Disorder Clinic IWK Health Centre 6th Floor Ambulatory Children’s Site 5850/5980 University Avenue PO Box 9700 [hemophilia.ca]

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Neonatal Respiratory Distress Syndrome

Even if the lung is opened in the DR, with or without the help of mask and bag ventilation, a noncompliant surfactant-deficient lung has a tendency to collapse and lung volume [journals.plos.org]

Respiratory tract disorders. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, eds. Nelson Textbook of Pediatrics. 20th ed. Philadelphia, PA: Elsevier; 2016:chap 101. [medlineplus.gov]

Babies with RDS need considerably higher PEEP than a baby with TTN or sepsis due to the noncompliant lungs. [intechopen.com]

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Osteosarcoma

Adnexal masses constitute a challenge especially in resource-limited countries like our own where poor access to health care and noncompliance are usually anticipated. [academic.oup.com]

Our specialists — including pediatric oncologists, surgical oncologists and radiation oncologists — offer a level of expertise in bone cancers rarely seen at other pediatric [dana-farber.org]

When prescribing antibiotics to the pediatric population, one also has to consider the probability of noncompliance to therapy. [emedicine.medscape.com]

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Febrile Seizures

[…] with drug administration, in part because of adverse effects of the medication. [pediatrics.aappublications.org]

Arch Pediatr. 2010;17:480-485. [ Links ] 19 Banerjee TK, Hazra A, Biswas A, Ray J, Roy T, Raut DK. Neurological disorders in children and adolescents. [scielo.br]

In a study by Farwell et al, 12 for example, children whose phenobarbital levels were in the therapeutic range had a reduction in recurrent seizures, but because noncompliance [pediatrics.aappublications.org]

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Familial Neutropenia

Altered venous tone may functionally affect the vein directly by contributing to venous noncompliance and a reduced venous capacity resulting in blood stasis, increased intraluminal [ahajournals.org]

[…] physician involved in the diagnosis of pediatric bone marrow disorders. [books.google.de]

[…] suspected pediatric age Corneal disorders ICD9CM Coronary artery disease unstable Cough chronic Creatine kinase elevation Cushings syndrome Cutaneous microvascular occlusion [books.google.com]

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