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977 Possible Causes for MELAS Syndrome

  • Cardiomyopathy

    The MELAS (mitochondrial encephalopathy, lactic acidosis, and strokelike) syndrome can manifest as cardiomyopathy.[clevelandclinicmeded.com] Mitochondrial diseases generally are systemic, in tissues with high metabolic activity, and give rise to syndromes.[clevelandclinicmeded.com]

  • Dementia

    Vascular dementia also occurs, but this in turn may be due to underlying conditions (including antiphospholipid syndrome, CADASIL, MELAS, homocystinuria, moyamoya, and Binswanger's[en.wikipedia.org]

  • Macular Degeneration

    Purpose: To explore differences in driving performance of older adults with age-related macular degeneration (AMD) and age-matched controls, and to identify the visual determinants of driving performance in this population. Methods: Participants included 33 older drivers with AMD (mean age [M] 76.6 6.1 years;[…][ncbi.nlm.nih.gov]

  • Mental Retardation

    Facioscapulohumeral muscular dystrophy (FSHD) is one of the most common muscular dystrophies which is related to the deletion of tandem repeats on chromosome 4q35. Extramuscular features such as hearing loss, retinopathy, mental retardation, and epilepsy, may be observed in patients carrying large 4q35 deletions[…][ncbi.nlm.nih.gov]

  • Brain Neoplasm

    Stereotactic radiosurgery (SRS) using the Gamma Knife (GK) is now being increasingly utilized for the treatment of brain metastases. However, there are a few reported cases of SRS-induced brain neoplasms. We herein report the case of a Japanese woman with metastatic non-small cell lung cancer (NSCLC) harboring[…][ncbi.nlm.nih.gov]

  • Cortical Blindness

    MELAS Syndrome Clinical Characteristics Ocular Features: This progressive mitochondrial disorder primarily affects muscles and the CNS, including the visual system.[disorders.eyes.arizona.edu] ., “MELAS Presented with Status Epilepticus and Anton-Babinski Syndrome; Value of ADC Mapping in MELAS,” Journal of Neuropsychiatry & Clinical Neurosciences, Vol. 19, No.[dx.doi.org] Genetics MELAS syndrome is a group of disorders caused by mutations in mitochondrial genes (at least 9 have been identified) that alter transfer RNA molecules resulting in[disorders.eyes.arizona.edu]

  • MELAS Syndrome

    Besides MELAS syndrome, MIDD syndrome, Pearson syndrome and Kearns-Sayre syndrome shall be mentioned as examples for clinical disorders triggered by mtDNA mutations. mtDNA[symptoma.com] This is the first report of Melas syndrome in Indian literature.[link.springer.com] The pathogenesis of DM in MELAS syndrome is not clear and there are no clinical studies evaluating glucose/insulin metabolism in individuals with MELAS syndrome.[grantome.com]

  • MERRF Syndrome

    […] of the families with MELAS syndrome (P 0.038; OR 2).[ncbi.nlm.nih.gov] So the patient’s clinical manifestations suggest the presence of a MERRF/MELAS overlap syndrome.[link.springer.com] […] loss heart abnormalities short stature For more information on MELAS and MERRF syndromes, visit the following links: For information on patient support for MELAS and MERRF[medschool.lsuhsc.edu]

  • Hypertension

    Topics: Hypertension 21/06/2007 00:00:00 Current versions available to download Current translated versions available to download: Authors Giuseppe Mancia, Co-Chairperson (Italy), Guy De Backer FESC, Co-Chairperson (Belgium), Anna Dominiczak (UK), Renata Cifkova FESC (Czech Republic), Robert Fagard FESC (Belgium),[…][web.archive.org]

  • Acidosis

    syndrome (Mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes) which is a rare mitochondrial disorder Prolonged lack of oxygen as a result of heart[symptoma.com] Differential diagnosis Differential diagnoses include other forms of Leigh syndrome and other possible causes of metabolic acidosis such as MELAS syndrome, glucose-6-phosphate[orpha.net] […] lactic acid - prolonged exercise, cancer, drinking excess alcohol, liver failure, hypoglycaemia, medications, e.g. salicylates, ethylene glycol (antifreeze) or methanol; MELAS[symptoma.com]

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