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154 Possible Causes for Mental Deterioration, Progressive Loss of Vision, Vegetative State

  • Neuronal Ceroid Lipofuscinosis

    state) or were too ill to travel.[ncbi.nlm.nih.gov] We report two sibs harbouring a novel mutation (p.Tyr258Asp) in the CLN5 gene and displaying behaviour disturbances and mental deterioration, rather than epilepsy, as the[ncbi.nlm.nih.gov] Most childhood forms of NCL are clinically characterized by progressive loss of vision as well as mental and motor deterioration, epileptic seizures, and premature death,[ncbi.nlm.nih.gov]

  • Parkinson's Disease

    […] and 239 controls) in a case-control study in western Washington State. b All assessed edible Solanaceae: green, yellow or red peppers, tomatoes, tomato juice, and baked or[doi.org] […] further and alleviates mental and physical suffering.[ncbi.nlm.nih.gov] This may lead to blurred vision; dark, floating spots in the vision; and progressive vision loss.[rarediseases.info.nih.gov]

  • Subacute Sclerosing Panencephalitis

    state.[ncbi.nlm.nih.gov] deterioration, behavioral changes, and myoclonic jerks.[ncbi.nlm.nih.gov] The authors here report a case of a 3-year-old child who presented with vision loss followed 15 months later by quadriparesis with bladder involvement.[ncbi.nlm.nih.gov]

  • Neuronal Ceroid Lipofuscinosis Type 7

    There is no cure available - treatment focus on management of symptoms - with patients progressing to a vegetative state and death 2,4 .[scielo.br] She had progressive motor and mental deterioration since the age of 2,5 years. Later she developed progressive vision loss, stereotypies, action myoclonus and epilepsy.[ncbi.nlm.nih.gov] EEG abnormality 0002353 Generalized myoclonic seizures 0002123 Global developmental delay 0001263 Juvenile onset Signs and symptoms begin before 15 years of age 0003621 Mental[rarediseases.info.nih.gov]

  • Neuronal Ceroid Lipofuscinosis Type 10

    There is no cure available - treatment focus on management of symptoms - with patients progressing to a vegetative state and death 2,4 .[scielo.br] Treatment options are limited to therapies that can help relieve some of the symptoms. 0001249 Mental deterioration Cognitive decline Cognitive decline, progressive Intellectual[rarediseases.info.nih.gov] JB disease first manifests as ataxia, progressive developmental milestone losses, epilepsy, and posterior vision losses in children of 2-4 years of age.[scielo.br]

  • Neuronal Ceroid Lipofuscinosis Type 3

    Seizures began at 10 years, and they died in their twenties after remaining in a vegetative state for several years ( Stengel 1826 ).[medlink.com] The typical early signs are loss of muscle coordination (ataxia) and seizures along with progressive mental deterioration.[brainfoundation.org.au] Like the other neuronal ceroid-lipofuscinoses, it is characterized by progressive loss of vision, seizures, and loss of cognitive and motor functions, leading to premature[ingentaconnect.com]

  • Cerebral Thrombosis

    […] neurologic status on heparin, failure to improve with heparin, large space-occupying parenchymal infarcts, deep venous thrombosis with altered mental status, or loss of consciousness[ajnrdigest.org] Protein S deficiency associated with progressive loss of vision and intracranial venous sinus thrombosis. J Chin Med Assoc 2004; 67(10):521-526. 27.[ispub.com] […] after admission occurs in approximately 23% of patients, with worsening of mental status, headache or focal deficits or with new symptoms such as seizures. [2] Mortality[annalsofian.org]

  • Infantile Neuroaxonal Dystrophy

    Severe spasticity, progressive cognitive decline and visual impairment can result in a vegetative state.[orpha.net] deterioration.[ncbi.nlm.nih.gov] The nerve endings responsible for carrying message to other parts of body are affected causing a progressive loss of vision and of physical and mental skills.[symptoma.com]

  • Rasmussen Syndrome

    The illness begins as behavioural disturbances, followed by myoclonic jerks, before ultimately resulting in dementia and a vegetative state.[smj.org.sg] We describe a case of Rasmussen syndrome in a 7-year-old boy, presenting with epilepsia partialis continua, hemiplegia, and progressive mental deterioration.[ncbi.nlm.nih.gov] These include weakness of one side of the body ( hemiparesis ), loss of vision for one side of the visual field ( hemianopia ), and cognitive difficulties (affecting learning[en.wikipedia.org]

  • Neonatal Adrenoleukodystrophy

    Social contact diminishes; at the end stage of the disease, the patient is in a vegetative state and dies after several years.[link.springer.com] It is characterized by adrenal atrophy and widespread cerebral demyelination, producing progressive mental deterioration, aphasia, apraxia, eventual blindness, and tetraplegia[medical-dictionary.thefreedictionary.com] Refsum disease is characterized by progressive loss of vision (retinitis pigmentosa); degenerative nerve disease (peripheral neuropathy); failure of muscle coordination (ataxia[rarediseases.org]

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