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526 Possible Causes for Mental Retardation, Spasticity - Hyperreflexia

  • Hallervorden-Spatz Syndrome

    Described features include 9,11 : progressive dementia extrapyramidal signs (rigidity, dystonia, choreoathetosis) corticospinal signs (spasticity, hyperreflexia) dysarthria[] Clinical presentations include dystonia, dysarthria, dementia, severe mental retardation and ataxia with rare features as rigidity, choreoathetosis, seizures, optic atrophy[] Spasticity, hyperreflexia, and other signs of corticospinal tract involvement are common and eventually limit ambulation.[]

  • Lesch Nyhan Syndrome

    In LNS patients there are three major signs of pyramidal dysfunction: spasticity, hyperreflexia and the extensor plantar reflex (also known as the Babinski reflex: the great[] Register The LESCH-NYHAN SYNDROME: Cerebral Palsy, Mental Retardation, and Self Mutilation - 24 Hours access EUR 36.00 GBP 28.00 USD 45.00 Rental This article is also available[] They also develop signs of pyramidal involvement including spasticity, hyperreflexia, and extensor plantar reflexes.[]

  • Autosomal Dominant Spastic Paraplegia Type 10

    ) is a rare type of hereditary spastic paraplegia that can present as either a pure form of spastic paraplegia with lower limb spasticity, hyperreflexia and extensor plantar[] SPG14 Gene Unknown 3q27-q28 Unknown Complicated: polineuropathy, mental retardation.[] […] can present as either a pure form of spastic paraplegia with lower limb spasticity, hyperreflexia and extensor plantar responses, presenting in childhood or adolescence, or[]

  • Klinefelter Syndrome

    This case showed spasticity and hyperreflexia with pathological reflexes and ankle clonus as well as muscle weakness in all extremities.[] This is the first description of KS, mosaicism (46,XY/47,XXY), associated with AN and mental retardation.[] Author information 1 Oasi Institute (IRCCS) for Research on Mental Retardation and Brain Aging, Troina, Italy., 2 Section of Endocrinology[]

  • Hereditary Spastic Paraplegia

    […] by progressive spasticity and hyperreflexia of the lower limbs HSMN V familial spastic paraplegia Strümpell-Lorrain disease French settlement disease Strumpell-Lorrain disease[] retardation and ichthyosis.[] HSP is generally classified as pure when lower limb spasticity and weakness, hyperreflexia, extensor-plantar responses, decreased vibration sense at the ankles, bladder dysfunction[]

  • Alexander Disease

    hyperreflexia, positive Babinski sign, gait abnormality, and weakness, though individual-to-individual and intrafamilial variability is seen [ Graff-Radford et al 2014 ].[] The patient initially presented at 9 months of age, with profound mental retardation and a history of seizures.[] Diffuse white matter involvement with frontal predominance is typical of infantile AD that is clinically characterized by progressive motor and mental retardation, seizures[]

  • Microcephalic Primordial Dwarfism due to ZNF335 Deficiency

    Related symptoms: Autosomal recessive inheritance Generalized hypotonia Nystagmus Spasticity Hyperreflexia SOURCES: MESH GARD UMLS OMIM MONDO More info about AICARDI-GOUTIERES[] Retardation , Autosomal Dominant 20 Mental Retardation , Autosomal Dominant 35 Mental Retardation , Autosomal Dominant 36 Mental Retardation , X-Linked 102 Mental Retardation[] , hyperreflexia, irritability, tremors, and seizures, but very little is known about early development.[]

  • Autosomal Dominant Spastic Paraplegia Type 17

    Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes more Clinical features from OMIM: 607584 UMLS symptoms related to Spastic Paraplegia[] Volcke Ph, Dereymaeker AM, Fryns JP, Van den Berghe H: On the nosology of moderate mental retardation with special attention to X-linked mental retardation.[] […] usually presents in late adolescence or early adulthood as a pure phenotype of lower limb spasticity with hyperreflexia and extensor plantar responses, as well as mild bladder[]

  • Autosomal Dominant Spastic Paraplegia Type 8

    24, Autosomal Recessive Symptoms via clinical synopsis from OMIM: 57 Neurologic Central Nervous System: spasticity hyperreflexia clonus difficulty standing walking on tiptoes[] Arena syndrome 0 *Spastic Paraplegia, Hereditary *Mental Retardation, X-Linked.[] Motor (83%) Distribution: Lower limb involvement Weakness Spastic paraplegia Progressive defecit Epilepsy (100%) Mental retardation: Variable severity Lipodystrophy with[]

  • Hydrocephalus

    , hyperreflexia Changes in vital signs resulting from brainstem compression due to herniation Because the fontanelles of infants are still open, the accumulation of CSF can[] Children with hydrocephalus have developmental defects of motor function, mental retardation, defective vision, and risk for epilepsy.[] Intelligence tests showed the man had an IQ of 75, below the average score of 100 but not considered mentally retarded or disabled, either.[]

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