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5,039 Possible Causes for Mental Retardation, Thin Brain Stem, Wide Space Between the First and Second Toe

  • Seckel Syndrome

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] It is extremely rare and typically causes dwarfism, mental retardation, intrauterine growth retardation and microcephaly.[symptoma.com] The syndrome is characterized by severe intrauterine and postnatal growth retardation with proportional dwarfism, typical beak-like triangular nose, and mental retardation[ncbi.nlm.nih.gov]

  • Down Syndrome

    Abstract Although there is considerable variability, most individuals with Down syndrome have mental retardation and speech and language deficits, particularly in language[oadoi.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[doi.org]

    Missing: Thin Brain Stem
  • Dubowitz Syndrome

    , short stature, microcephaly, mild mental retardation with behavior problems, eczema, and unusual and distinctive faci DUBOWITZ SYNDROME edit English Dubowitz syndrome Human[wikidata.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Dubowitz syndrome is an autosomal recessive disorder of growth retardation, characteristic face, mild mental retardation, and eczema originally described by Dubowitz [1965[ncbi.nlm.nih.gov]

    Missing: Thin Brain Stem
  • Ring Chromosome 10

    1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] deficiency Mental retardation Mental retardation, nonspecific Mental-retardation [ more ] 0001249 Intrauterine growth retardation Prenatal growth deficiency Prenatal growth[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

    Missing: Thin Brain Stem
  • Subependymal Giant Cell Astrocytoma

    Although the name infers to its origin of the ‘subependymal’ zone, which is a thin layer of cells with stem cell-like features along the lateral wall of lateral ventricles[nature.com] retardation.[ncbi.nlm.nih.gov] Spinal cord : The column of nerve tissue that runs from the brain stem down the center of the back. It is covered by three thin layers of tissue called membranes.[northshore.org]

    Missing: Wide Space Between the First and Second Toe
  • Alexander Disease

    The cervical spinal cord was already thin at the first observation. 17 In patient 3, brain stem atrophy and WM abnormalities progressed for 7 years.[ajnr.org] The patient initially presented at 9 months of age, with profound mental retardation and a history of seizures.[ncbi.nlm.nih.gov] Diffuse white matter involvement with frontal predominance is typical of infantile AD that is clinically characterized by progressive motor and mental retardation, seizures[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Smith-Magenis Syndrome

    One patient had subependymal periventricular gray matter heterotopia, and the second had a thin corpus callosum, a thin brain stem and hypoplasia of the cerebellar vermis.[ncbi.nlm.nih.gov] Smith-Magenis syndrome (SMS) is a rare syndrome with multiple congenital malformations, including development and mental retardation, behavioral problems and a distinct facial[ncbi.nlm.nih.gov] Since then, mental retardation, particularly in terms of language development, became increasingly more obvious.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Waisman Syndrome

    The cervical spinal cord was already thin at the first observation. 17 In patient 3, brain stem atrophy and WM abnormalities progressed for 7 years.[ajnr.org] Abstract Linkage of the gene responsible for an X-linked early onset parkinsonism disorder with mental retardation (McKusick 311510) to DNA probes that detect restriction[ncbi.nlm.nih.gov] (redirected from Waisman syndrome ) Parkinsonism, early onset with mental retardation An extremely rare (one cohort documented in the world literature) condition (OMIM:311510[medical-dictionary.thefreedictionary.com]

    Missing: Wide Space Between the First and Second Toe
  • Microcephaly

    Working with lab-grown human stem cells, scientists found that the virus selectively infected cells forming the brain’s cortex, the thin outer layer of folded gray matter.[bostonglobe.com] No clear consensus has been established regarding the management of oral cancer in patients with mental retardation.[ncbi.nlm.nih.gov] Hyperphosphatasia with mental retardation syndrome-3 is an autosomal recessive disorder usually characterized by severe mental retardation.[ncbi.nlm.nih.gov]

    Missing: Wide Space Between the First and Second Toe
  • Neurofibromatosis Type 1

    stem glioma Fig 1.[ajnr.org] All patients with uncontrolled seizures had severe mental retardation, and three of these had malformations of cortical development.[ncbi.nlm.nih.gov] A much smaller percentage experience more significant cognitive difficulties such as mild or moderate mental retardation.[emedicine.com]

    Missing: Wide Space Between the First and Second Toe

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