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5,061 Possible Causes for metabolite

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  • Influenza

    Although its aetiopathogenesis is not exactly known, it is thought that inefficient drug detoxification leading to the accumulation of drug reactive metabolites causes autoimmune[]

  • Urinary Tract Infection

    BACKGROUND: Indoleamine-2,3-dioxygenase (IDO) catalyzes the first step of tryptophan (Trp) catabolism, yielding kynurenine (Kyn) metabolites.[] […] with pyuria as demonstrated by a positive leucocyte esterase test; (2) To detect the mean number of new symptomatic culture-confirmed UTIs; (3) To quantify urinary PACs metabolites[]

  • Skin Infection

    Within the first 24 h, S. aureus transcripts involved in DNA repair, metabolite transport, and metabolism were up-regulated, suggesting an increase in the machinery encoding[]

  • Sunburn

    Anti-inflammatory metabolite 15-HETE shows later expression, peaking at 72 h.[] Abstract Like UV irradiation, which generates vitamin D(3) in the skin, the hormonally active metabolite, 1,25-dihydroxyvitamin D(3), boosts innate immunity against viruses[] While COX-derived prostaglandin (PG)E(2) is a potent mediator of sunburn vasodilatation, LOX-derived 15-hydroxyeicosatetraenoic acid (HETE) and its lipoxin metabolites may[]

  • Infectious Mononucleosis

    The results of the drug-induced lymphocyte stimulation test tests suggested that 5-aminosalicylic acid was a possible causative metabolite.[]

  • Appendicitis

    A biopattern comprised of 9 metabolites and 7 inflammatory compounds was detected to be significant for the separation between appendicitis and control groups.[]

  • Idiopathic Pulmonary Fibrosis

    Via these actions, melatonin and its metabolites modulate a variety of molecular pathways in different pathophysiological conditions.[] Among them, we identified one metabolite at a retention time of 9.59 min that was two times more abundant in the serum of IPF patients compared to healthy participants.[] By comparing the variations in the lipid metabolite levels in IPF patients, a total of 62 unique lipids were identified by statistical analysis including 24 kinds of glycerophoslipids[]

  • Adrenal Insufficiency

    […] patients with pediatric-onset primary adrenal insufficiency (PAI), such as 21-hydroxylase deficiency, can be diagnosed by measuring the urine or serum levels of steroid metabolites[]

  • Osteoporosis

    Nine urinary PAHs (U-PAHs) metabolites were measured as exposure biomarkers.[] The vitamin D metabolite 1,25-dihydroxycholecalciferol is the active hormone that helps maintain normal serum calcium and phosphate levels.[] Several medications under study include other bisphosphonates that slow bone breakdown (like alendronate), sodium fluoride, vitamin D metabolites, and selective estrogen receptor[]

  • Streptococcal Infection

    The CSF neurotransmitter metabolites tetrahydrobiopterin and neopterin profiles were normal. CSF hypocretin was 8.6 pg/nL (normal 110 pcg/nL).[]

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