Metaphyseal Cupping: Causes & Reasons

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Possible Causes for Metaphyseal Cupping

Spondyloepimetaphyseal Dysplasia Type Missouri

cupping 0003021 Platyspondyly Flattened vertebrae 0000926 Radial bowing Bowing of outer large bone of the forearm 0002986 Rhizomelia Disproportionately short upper portion [rarediseases.info.nih.gov]

Decreased elbow extension Elbow limited extension Limitation of elbow extension Limited extension at elbows Limited forearm extension Restricted elbow extension [ more ] 0001377 Metaphyseal [rarediseases.info.nih.gov]

Platyspondyly

Bone abnormalities include a distinctive metaphyseal cupping of the metacarpals, metatarsals, and phalanges. [malacards.org]

Metaphyseal Acroscyphodysplasia

Title Other Names: Cupped metaphyses and cone-shaped epiphyses of knees with brachydactyly; Wedge-shaped epiphyses of knees; Bellini syndrome; Cupped metaphyses and cone-shaped [rarediseases.info.nih.gov]

MalaCards based summary : Metaphyseal Acroscyphodysplasia, is also known as cupped metaphyses and cone-shaped epiphyses of knees with brachydactyly. [malacards.org]

Based on two independent personal cases and a pair of sibs from the literature, we delineate a new category of bone dysplasia with cup-shaped large metaphyses, for which the [ncbi.nlm.nih.gov]

Metaphyseal Chondrodysplasia Type Schmid

These changes were subtle and consisted of shortening of the tubular bones and metaphyseal cupping of the proximal phalanges and metacarpals. [ncbi.nlm.nih.gov]

[…] chondrodysplasia ; Metaphyseal cupping of metacarpals ; Metaphyseal cupping of proximal phalanges ; Mild short stature ; Platyspondyly ; Proximal femoral metaphyseal abnormality [mousephenotype.org]

[…] chondrodysplasia 0005871 Metaphyseal cupping of metacarpals Cupping of wide portion of long bone of hand 0006028 Metaphyseal cupping of proximal phalanges 0006208 Mild short [rarediseases.info.nih.gov]

Metaphyseal Chondrodysplasia, Spahr Type

Pathology Classification Schmid type - mild type, due to mutation in type X collagen ( COL10A1 gene), metaphyses are cupped resembling rickets Pena and Vaandrager type - intermediate [radiopaedia.org]

Pathology Sub types Schmid type - mutation in collagen type 10 results in mild type where the metaphyses are cupped resembling ri... [abarcos2.kianblog.com]

Major radiographic features in infancy included flared,cupped, and ragged metaphyses of all long bones, delayedmaturation of the scaphoid, trapezoid, and trapezium bones,wide [docslide.net]

Infantile Scurvy

A five year old girl presented with short femora, cupped distal metaphyses and flexion deformity of the knees suggesting previous epiphyseo-metaphyseal damage. [ncbi.nlm.nih.gov]

[…] band underlying Frankel line Pelkan spur: metaphyseal spurs which result in cupping of the metaphysis Adults osteopenia pathological fractures Other significant manifestations [radiopaedia.org]

[…] radiologic shadow surrounding epiphyseal centers of ossification, which may result from bleeding Frankel line: dense zone of provisional calcification Trümmerfeld zone: lucent metaphyseal [radiopaedia.org]

Spondylometaphyseal Dysplasia Type Kozlowski

The original report describes an Iranian infant with mild rhizomelic limb shortening, severe metaphyseal cupping and irregularity and platyspondyly who died shortly after [ncbi.nlm.nih.gov]

[…] is a rare, perinatally lethal osteochondrodysplasia comprising minor facial, cardiac and cerebral anomalies, rhizomelic shortness of long bones, metaphyseal cupping and irregularity [updoc.site]

KEY WORDS: lethal chondrodysplasia; platyspondyly; metaphyseal dysplasia; Sedaghatian dysplasia; AR inheritance INTRODUCTION Spondylometaphyseal dysplasia type Sedaghatian [updoc.site]

Thoracolaryngopelvic Dysplasia

Long bones in Shwachman syndrome may show some metaphyseal cupping, which may cause confusion with neonatal rickets (9). [czytelniamedyczna.pl]

[…] chondrodysplasia (OMIM 250220; short ribs with splayed posterior ends and cupped anterior ribs ends, mildly shortened tubular bones with metaphyseal cupping and irregularity [journals.lww.com]

cupping and fraying of tubular bones have also been observed in Jansen metaphyseal dysplasia (OMIM 156400), which differs by the presence of splayed rib ends and normal alkaline [journals.lww.com]

Ulna Metaphyseal Dysplasia Syndrome

Features include growth plate widening, decreased density, and irregularities in the zone of provisional calcification, metaphyseal cupping and fraying, increased epi-metaphyseal [rrnursingschool.biz]

The cupped metaphyses with pointed edges at birth are another distinctive feature. [czytelniamedyczna.pl]

Shortening of long bones with cupped and widened metaphyses was also noted. [mjdrdypu.org]

Facioauriculoradial Dysplasia

Anteroposterior radiograph of the upper limbs after the reconstruction showed profound radial aplasia, metaphyseal cupping associated with hypoplastic/defective ossification [casesjournal.biomedcentral.com]

Figure 2 Anteroposterior radiograph of the upper limbs after the reconstruction showed profound radial aplasia, metaphyseal cupping associated with hypoplastic/defective ossification [casesjournal.biomedcentral.com]

Metaphyseal Anadysplasia

The metaphyses show mild fraying, cupping, and widening ► [Coarse, frayed, disorganized metaphyses with edge indistinctness] As anticipated above in the section "Metaphyseal [rrnursingschool.biz]

Regression after the age of 10 years Premature fusion of the femoral and tibial epihyses in their metaphyses Cupping metaphyses and cone epiphyses Coronal cleft vertebrae [updoc.site]

Roentgenographic bone changes consisting of splaying, cupping and irregularity of the metaphyses with deep radiolucent metaphyseal defects and bicentric ossification of the [semanticscholar.org]

Platyspondylic Lethal Skeletal Dysplasia Type Torrance

[…] tubular bones with splayed and cupped metaphyses. [malacards.org]

cupping [genatlas.medecine.univ-paris5.fr]

cupping MedGen UID: 323062 • Concept ID: C1837082 • Finding Metaphyseal cupping refers to an inward bulging of the metaphyseal profile giving the metaphysis a cup-like appearance [ncbi.nlm.nih.gov]

X-Linked Dominant Chondrodysplasia Type Chassaing-Lacombe

Bone abnormalities include a distinctive metaphyseal cupping of the metacarpals, metatarsals, and phalanges. [malacards.org]

[…] chondrodysplasia Severe platyspondyly Metaphyseal cupping of metacarpals Hypoplasia of the calcaneus Cutis laxa Hyperextensible skin Encephalopathy Nephrotic syndrome Low-set [mendelian.co]

cupping of proximal phalanges Underdeveloped supraorbital ridges Aplasia/Hypoplasia of the eyebrow Generalized hyperpigmentation Hallux valgus Curly hair Dystrophic fingernails [mendelian.co]

Spondyloepimetaphyseal Dysplasia Type Irapa

Note the major delay in epi physeal ossification, the metaphyseal cupping and the severe platyspondyly. [yumpu.com]

cupping and irregularity, platyspondyly, delayed epiphyseal ossification, irregular ‘‘lacy’’ iliac crests, and brachydactyly. [wbzwqaiy.gq]

Bellini-Chiumello-Rinoldi Syndrome

[…] dysplasia characterized by the distinctive radiological sign of cone-shaped upper tibial and lower femoral epiphyses embedded in large cup-shaped metaphyses, associated with [orpha.net]

Homepage Rare diseases Search Search for a rare disease Metaphyseal acroscyphodysplasia Disease definition Metaphyseal acroscyphodysplasia is an extremely rare form of metaphyseal [orpha.net]

Spondyloepimetaphyseal Dysplasia Type Bieganski

cupping (metacarpals and phalanges) Skeletal Pelvis: coxa vara flared iliac wings short, hypoplastic femoral necks cone-shaped capital femoral epiphyses Head And Neck Face [malacards.org]

The long bones showed widened metaphyses with increasedtransradiancy and abnormal trabecular pattern. The metaphyses ofthe short tubular bones were cupped. [docslide.net]

The distal tibial metaphyses were flared andshowed a peg-like central prominence. The humeral and the distalforearm ossification centres were absent. [myslide.es]

Fibrochondrogenesis

The ribs are typically short and wide and have metaphyseal cupping at both ends (summary by {9:Tompson et al., 2010}). [diseaseinfosearch.org]

Short, broad dumbell-shaped metaphyses. Pear shaped vertebral bodies. Short, distally cupped ribs. Eteson DJ, Adomian GE, Ornoy A et.al. [fetalultrasound.com]

Ribs are short and wide, cupped both anteriorly and posteriorly. The long bones are short and broad (dumb-bell shaped) with irregular metaphyses and peripheral spurs. [ncbi.nlm.nih.gov]

Vitamin D-Dependent Rickets

cupping Looser's zones (pseudofracture on the compression side of bone) decreased bone density prominence of rib heads at the osteochondral junction ( rachitic rosary ) bowing [orthobullets.com]

The distal radial and ulnar metaphyses were cup-shaped, and the distal femoral and proximal tibial metaphyses were slightly widened. [pedsinreview.aappublications.org]

Shaft head looks like a cup; Osteo-cartilaginous junction looks fringe, with a vague contour. Chest radiograph y : anterior extremities of the ribs are enlarged. [doctortipster.com]

Thin Ribs - Tubular Bones - Dysmorphism Syndrome

Cupping, fraying, and splaying of the metaphyses, most prominent in the lower extremities and in the lower femurs, are common features. [rrnursingschool.biz]

In a 13-month- old girl 1 month after the beginning of treatment the metaphyses are cupped, with a marginal band of increased density due to recalcification of the provisional [rrnursingschool.biz]

Spondylometaphyseal Dysplasia Type East African

Metaphyseal cupping MedGen UID: 323062 • Concept ID: C1837082 • Finding Metaphyseal cupping refers to an inward bulging of the metaphyseal profile giving the metaphysis a [ncbi.nlm.nih.gov]

cup-like appearance. [ncbi.nlm.nih.gov]

Hypospadias - Intellectual Disability Syndrome Type Goldblatt

cupping Congenital adrenal hypoplasia Mandibular prognathia Gastroesophageal reflux Protruding ear Camptodactyly Metaphyseal dysplasia Tapered finger Single transverse palmar [mendelian.co]

Oculomotor apraxia Stereotypy Respiratory tract infection Long palpebral fissure Finger syndactyly Adrenal insufficiency Mania Primary adrenal insufficiency Adrenal hypoplasia Metaphyseal [mendelian.co]

Microphthalmia - Ankyloblepharon - Intellectual Disability Syndrome

Distal shortening of limbs Metaphyseal cupping of metacarpals 11 pairs of ribs Oxycephaly Decreased skull ossification Hypoplastic iliac wing Thin ribs Rhizomelia X-linked [mendelian.co]

[…] chondrodysplasia Intellectual disability, moderate Hyperhidrosis Alopecia Hypoplasia of the calcaneus Metaphyseal cupping of proximal phalanges Abnormality of the calcaneus [mendelian.co]

[…] eyebrow Aplasia/Hypoplasia of the eyebrow Finger clinodactyly Preauricular skin tag Recurrent pneumonia Brachydactyly Hydrocephalus Cerebellar hypoplasia Craniosynostosis Metaphyseal [mendelian.co]

Spondyloepimetaphyseal Dysplasia Type Shohat

Note the major delay in epi physeal ossification, the metaphyseal cupping and the severe platyspondyly. [yumpu.com]

The cupped metaphyses with pointed edges at birth are another distinctive feature. [czytelniamedyczna.pl]

One of the signs of rickets that doctors look for is cupping and fraying at the metaphyses when seen on X-ray. [wikivisually.com]

Spondyloenchondrodysplasia

The distal femoral and the proximal tibial bones show metaphyseal cupping with multiple enchondromatous lesions and an abnormal metaphyseal trabecular pattern associated with [gooa.las.ac.cn]

Figure 2 Anteroposterior radiograph of the knee showing multiple small enchondroma-like metaphyseal dysplasias. [jmedicalcasereports.biomedcentral.com]

One of the signs of rickets that doctors look for is cupping and fraying at the metaphyses when seen on X-ray. [wikivisually.com]

Schneckenbecken Dysplasia

cupping, squared iliac bones, horizontal acetabular roofs, hypoplastic ischia and pubis. read more Next Generation Sequencing NGS/Del Dup Comprehensive Turnaround Time: Typically [ctgt.net]

Advanced ossification of carpal bones Brachydactyly Flat acetabular roof Midface retrusion Ovoid vertebral bodies Metaphyseal irregularity (Source: Schneckenbecken Dysplasia [dovemed.com]

Asphyxiating Thoracic Dysplasia

Long bones in Shwachman syndrome may show some metaphyseal cupping, which may cause confusion with neonatal rickets (9). [czytelniamedyczna.pl]

Dappled Diaphyseal Dysplasia

The ribs are typically short and wide and have metaphyseal cupping at both ends (summary by Tompson et al., 2010 ). [mendelian.co]

cupping Finger syndactyly Postaxial polydactyly Amenorrhea Tetralogy of Fallot Primary amenorrhea Lymphedema Abnormal vertebral morphology Congenital hip dislocation Multicystic [mendelian.co]

[…] limb shortening Decreased cranial base ossification Failure to thrive Cryptorchidism High palate Atrial septal defect Hypospadias Obesity Rod-cone dystrophy Hydronephrosis Metaphyseal [mendelian.co]

Metaphyseal Chondrodysplasia Type Jansen

[…] chondrodysplasia 0005871 Metaphyseal cupping 0003021 Micrognathia Little lower jaw Small jaw Small lower jaw [ more ] 0000347 Misalignment of teeth Abnormal dental position [rarediseases.info.nih.gov]

One of the signs of rickets that doctors look for is cupping and fraying at the metaphyses when seen on X-ray. [wikivisually.com]

Metaphyseal Chondrodysplasia Type Kaitila

[…] band Alternating radiolucent and dense metaphyseal bands Solitary dense metaphyseal band Dense vertical metaphyseal lines Fraying of the metaphyses Cupping of metaphyses [gentili.net]

(a) At the age of 3 days metaphyseal cupping and irregularity is seen in the distal ulna and radius as well as in the metacarpals. [studyres.com]

In addition to the cone epiphysis of the middle phalanx of the forefinger, the metaphyses are abnormally cupped. The fingers are equal in length. [documents.tips]

Osteoglophonic Dwarfism

Cupping," marked changes around the metaphyses, including undermineralization of the provisional zone, widening, cupping, and fraying, are characteristic features in rickets [rrnursingschool.biz]

The bones are undermineralized. b In images taken when the boy was 7 years old severe metaphyseal changes have developed, with metaphyseal widening, cupping, and a typical [rrnursingschool.biz]