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103 Possible Causes for Metaphyseal Spurring

  • Saldino-Noonan Syndrome

    Longitudinal metaphyseal spurs Vertebral abnormalities[] Longitudinal metaphyseal spurs Vertebral abnormalities Adapted from reference 6.[] Type III (Naymoff): wide metaphyses with spurs. Type IV (Beemer-Langer ): median cleft lip and ambiguous genitalia in some 46,XY individuals.[]

  • Achondrogenesis Type 1B

    spurring of long bones ulna and fibula are not ossified in most cases short bones of hands and feet are very poorly ossified and sometimes there is bipartite ossification[] Metaphyseal spurring gives the appearance of a "thorn apple" or (for hematologic experts) "acanthocyte."[] […] much shorter than normal with cupping of distal ends the iliac bones are smaller than usual and only their upper half is irregularly ossified there is severe shortening and metaphyseal[]

  • Menkes Disease

    Skeletal findings in infants with Menkes disease, the most characteristic of which are metaphyseal spurs, long-bone fractures and wormian bones, have been widely reported.[] These lesions associated with femoral metaphyseal spurs could be confused with nonaccidental injury such as that seen in the shaken baby syndrome.[] Radiographs show generalized osteoporosis, metaphyseal flaring and spurs in the long bones, diaphyseal periosteal reaction and thickening, and Wormian bones in the cranial[]

  • Fracture

    Radiologic changes that should lead to further evaluation for possible deficiency include cupping and fraying of the metaphyses, sickle-shaped metaphyseal spurs, significant[]

  • Hyponatremia

    Stillborn infants typically have irregular, short, and deep cup-shaped metaphyses, hypoplastic or absent bones, and thin diaphysis.[] Rachitic rib changes, flail chest, and metaphyseal dysplasia (proximal humerus) in infantile hypophosphatasia Table 1.[] In utero-affected fetuses have decreased bone mineralization, short and/or bowed long bones, and spur-like projections of the long bones.[]

  • Osteoporosis

    Rachitic rib changes, flail chest, and metaphyseal dysplasia (proximal humerus) in infantile hypophosphatasia Table 1.[] Clinical Features of Hypophosphatasia by Type Type Inheritance Cardinal Features Dental Features Clinical Diagnosis Perinatal (severe) AR Hypomineralization, osteochondral spurs[]

  • Short Rib-Polydactyly Syndrome

    Polydactyly, micromelia, metaphyseal spurs, widened humeral metaphyses, and shortened ribs can be prominent prenatal ultrasound findings of SRPS III.[] , metaphyseal spurs) (Naumoff et al. 1977; Verma et al. 1975).[] […] marked longitudinal spurs PAS-positive and diastase-resistant cytoplasmic inclusion bodies "bajonet" deformity of the ribs for misalignment and overlap of cartilaginous and[]

  • Thoracomelic Dysplasia

    spurs Juvenile onset Scapular exostoses Rib exostoses Pelvic bone exostoses Osteochondroma Cervical myelopathy Multiple exostoses Chondrosarcoma Osteosarcoma Exostoses Short[] […] finger Sarcoma Metaphyseal dysplasia Glaucoma Abnormality of the foot Depressivity Coma Neoplasm Milia Pica Metaphyseal widening Osteoarthritis Limitation of joint mobility[] Short palm Conductive hearing impairment Spondyloepimetaphyseal dysplasia Enlarged joints Narrow iliac wings Hypoplastic pubic bone Dysplastic iliac wings Nystagmus Kyphosis Metaphyseal[]

  • Subperiosteal Hemorrhage

    Findings on plain radiographs include a lucent transverse metaphyseal band with an adjacent dense sclerotic band, metaphyseal spurring, and nonspecific evidence of diffuse[] Irregularity of the metaphyseal margins frequently occurs secondary to infarctions of the epiphyseal- metaphyseal junction. 3. Pelken’s spurs. 4.[] JSS Medical College, Mysuru PELKAN’S SPUR • Zone of provisional calcification extends beyond the margins of the metaphysis resulting in periosteal elevation and marginal spur[]

  • Thoracolaryngopelvic Dysplasia

    , metaphyseal spurs) (Naumoff et al. 1977; Verma et al. 1975).[] , and marked longitudinal spurs Short rib syndrome (Beemer-Langer syndrome) (OMIM 269860): This is a lethal entity characterized by hydrops, ascites, median cleft of the upper[] […] extending caudally from the acetabular roof), metatropic dysplasia (OMIM 156530; mushrooming of the long tubular bones), and lethal metaphyseal chondrodysplasia (OMIM 250220[]

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