## Most common diseases

#### Amish Lethal Microcephaly

*3*, 4, *5*, 6, 7 ].
[mdpi.com]

Other studies define severe *microcephaly* as greater than three *SD* *below* the *mean*, which includes about 0.1% of the population [ 1, 8, 9, 10 ].
[mdpi.com]

*Microcephaly* is defined as a head circumference more than two standard deviations (*SD*) *below* the *mean* for gender and age, which includes about 2% of the population [ 1, 2,
[mdpi.com]

#### Zika Virus Disease

Male 36 (55) *3* (60) Female 29 (45) 2 (40) Degree of *microcephaly* (n 60) (n *5*) Severe ( *3* *SD* *below* *mean* for gestational age) 39 (65) 4 (100) Other ( 3 SD below mean for gestational
[doi.org]

9 (16) 0 (—) Timing of rash during pregnancy (n 49) (n 5) First trimester 37 (76) 4 (80) Second trimester 10 (20) 1 (20) Third trimester 2 (4) 0 (—) Infant sex (n 65) (n *5*)
[doi.org]

#### Microcephalic Primordial Dwarfism Type Alazami

Abstract Primordial dwarfism (PD) is a clinically and genetically heterogeneous condition. Various molecular mechanisms are known to underlie the disease including impaired mitotic mechanics, abnormal IGF2 expression, perturbed DNA damage response, defective spliceosomal machinery, and abnormal replication licensing. Here,[…] [unboundmedicine.com]

#### Autosomal Recessive Primary Microcephaly Type 13

*3*, 4, *5*, 6, 7 ].
[mdpi.com]

Other studies define severe *microcephaly* as greater than three *SD* *below* the *mean*, which includes about 0.1% of the population [ 1, 8, 9, 10 ].
[mdpi.com]

*Microcephaly* is defined as a head circumference more than two standard deviations (*SD*) *below* the *mean* for gender and age, which includes about 2% of the population [ 1, 2,
[mdpi.com]

#### Autosomal Recessive Primary Microcephaly Type 11

*3*, 4, *5*, 6, 7 ].
[mdpi.com]

Other studies define severe *microcephaly* as greater than three *SD* *below* the *mean*, which includes about 0.1% of the population [ 1, 8, 9, 10 ].
[mdpi.com]

*Microcephaly* is defined as a head circumference more than two standard deviations (*SD*) *below* the *mean* for gender and age, which includes about 2% of the population [ 1, 2,
[mdpi.com]

#### Autosomal Recessive Primary Microcephaly Type 12

*3*, 4, *5*, 6, 7 ].
[mdpi.com]

*microcephaly* as greater than three *SD* *below* the *mean*, which includes about 0.1% of the population [ 1, 8, 9, 10 ].
[mdpi.com]

*Microcephaly* is defined as a head circumference more than two standard deviations (*SD*) *below* the *mean* for gender and age, which includes about 2% of the population [ 1, 2,
[mdpi.com]

#### Absent Tibia - Polydactyly - Arachnoid Cyst Syndrome

*Microcephaly* The diagnosis of *microcephaly* is more likely to be accurate when the head circumference is *3* *SD* *below* the *mean* for dates ( Table 12 ). 4, *5* A definitive diagnosis
[glowm.com]

#### Ventriculomegaly-Cystic Kidney Disease

*Microcephaly* The diagnosis of *microcephaly* is more likely to be accurate when the head circumference is *3* *SD* *below* the *mean* for dates ( Table 12 ). 4, *5* A definitive diagnosis
[glowm.com]

#### Dilation of Vein of Galen

*Microcephaly* The diagnosis of *microcephaly* is more likely to be accurate when the head circumference is *3* *SD* *below* the *mean* for dates ( Table 12 ). 4, *5* A definitive diagnosis
[glowm.com]