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25 Possible Causes for Microcephaly (5 SD)

Did you mean: Microcephaly (5 SD

  • Macrocephaly

    Our patient has significant macrocephaly ( 5 SD) and Arnold–Chiari malformation type I.[nature.com] So far, all described patients with ARID1B changes have HC within normal limits or demonstrated microcephaly, except for one patient in Hoyer et al 12 and one in Wieczorek[nature.com]

  • Lissencephaly

    However, three fourths of patients also showed variable congenital and postnatal microcephaly, up to -5 SD.[ncbi.nlm.nih.gov]

  • Severe Neonatal-Onset Encephalopathy with Microcephaly

    . Incidence of moderate to severe mental retardation  HC from 2-3 SD below the age is 33%.  HC 3 SD, incidence is 62% Not always associated with mental retardation 5.[slideshare.net] […] types of microcephaly Primary microcephaly  Secondary microcephaly (non (genetic) genetic /acquired) primary defect in brain development  prenatal onset  prenatal onset[slideshare.net]

  • Microcephaly

    In all cases, microcephaly proceeded to worsen with age reaching 5 to 10 SD at last evaluation.[doi.org] All presented initially with a minor or mild microcephaly from 1 to 3 standard deviations (SD) without growth deficiency.[doi.org]

  • Cernunnos-XLF Deficiency

    (-5 SD) significant microcephaly (-5 SD) birdlike face birdlike face growth retardation ( 5 Immunologic investigation IgG 120-530 mg/dl, IgG 120-530 mg/dl, IgA 6-18 mg/dl[slideplayer.com] […] months) recurrent bacterial and viral infections of upper and lower respiratory tract since infancy period (otitis, bronchitis and pneumonitis every 2 months) significant microcephaly[slideplayer.com]

  • Autosomal Dominant Mental Retardation 28

    Common features included microcephaly (-2.1 to -3.0 SD), poor overall growth, and delayed psychomotor development with intellectual disability and absent speech.[findzebra.com] […] is caused by heterozygous mutation in the KAT6A gene (601408) on chromosome 8p11.Arboleda et al. (2015) reported 4 unrelated children, ranging from 2 years, 11 months to 5[findzebra.com]

  • Seckel Syndrome

    Characteristics of Seckel syndrome include severe proportionally short stature with severe microcephaly (mean postnatal growth retardation is -7SD with a range from -5 to[dnatesting.uchicago.edu] -13 SD; mean OFC is -9SD with a range from -4 to -14SD), a ‘bird like’ profile include a receding forehead, large eyes, beak-like protusion of the nose, narrow face, receding[dnatesting.uchicago.edu] Seckel syndrome belongs to the microcephalic osteodysplastic dwarfism group characterized by intrauterine growth retardation, dwarfism, and microcephaly.[dnatesting.uchicago.edu]

  • Cerebro-Costo-Mandibular Syndrome

    Common features included microcephaly (-2.1 to -3.0 SD), poor overall growth, and delayed psychomotor development with intellectual disability and absent speech.[findzebra.com] […] is caused by heterozygous mutation in the KAT6A gene (601408) on chromosome 8p11.Arboleda et al. (2015) reported 4 unrelated children, ranging from 2 years, 11 months to 5[findzebra.com]

  • Hyperextensible Joints

    Likewise, bone age is reported as delayed in younger ages and advanced in older children. 5 Head size The median occipto-frontal circumference (OFC) SDS at birth was -0.8[nanopdf.com] The most severe case of microcephaly was that of Tohyama et al (-3.9 SDS)[42] but the child was genetically atypical in that there was an additional marker chromosome and[nanopdf.com]

  • Zika Virus Disease

    Male 36 (55) 3 (60) Female 29 (45) 2 (40) Degree of microcephaly (n 60) (n 5) Severe ( 3 SD below mean for gestational age) 39 (65) 4 (100) Other ( 3 SD below mean for gestational[doi.org] 9 (16) 0 (—) Timing of rash during pregnancy (n 49) (n 5) First trimester 37 (76) 4 (80) Second trimester 10 (20) 1 (20) Third trimester 2 (4) 0 (—) Infant sex (n 65) (n 5)[doi.org]

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