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848 Possible Causes for Microcytic Anemia

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  • Sideroblastic Anemia

    The characteristic hypochromic, microcytic anemia typically becomes manifest in the first three decades of life.[ncbi.nlm.nih.gov] Abstract Sideroblastic anemia is a rare cause of microcytic hypochromic anemia.[ncbi.nlm.nih.gov] Hemizygous males have microcytic anemia and iron overload.[ncbi.nlm.nih.gov]

  • Alpha Thalassemia

    MATERIAL AND METHODS: Two hundred six patients with hypochromic microcytic anemia were evaluated for alpha thalassemia.[ncbi.nlm.nih.gov] Note : Thalassemia is a microcytic, hypochromic anemia. Its cause is a genetically based decreased synthesis of one or several globin chains.[lecturio.com] The proband, a 36 year-old male, presented with chronic borderline anemia and microcytic hypochromic parameters.[ncbi.nlm.nih.gov]

  • Iron Deficiency Anemia

    Abstract Iron-refractory iron deficiency anemia (IRIDA) is a rare autosomal recessive disease characterized by congenital hypochromic microcytic anemia, low transferrin saturation[ncbi.nlm.nih.gov] Patients have hypochromic microcytic anemia refractory to oral iron and are only partially responsive to parenteral iron administration.[ncbi.nlm.nih.gov] ; iron deficiency anemia; microcytic anemia; β-Thalassemia (β-thal)[ncbi.nlm.nih.gov]

  • Anemia of Chronic Disease

    Conclusions: CD should be included in the differential diagnosis of microcytic anemia.[doi.org] Functional ID leads to a reduction in red cell hemoglobiniza-tion, causing hypochromic microcytic anemia.[ncbi.nlm.nih.gov] Iron deficiency anemia (IDA) and anemia of chronic disease (ACD) are the most prevalent, both characterized by hypochromic microcytic anemia and low serum iron (SI).[ncbi.nlm.nih.gov]

  • Haemoglobin E Disease

    Hb E disease (homozygous Hb E, Hb EE) is also a benign disorder with a mild microcytic anemia (average MCV 62 fl, Hgb 12 g/dl).[path.upmc.edu] In homozygotes, a mild microcytic anemia with prominent target cells exists. Diagnosis of hemoglobin E disorders is by hemoglobin electrophoresis.[msdmanuals.com] Patients present with a moderate to severe microcytic anemia (average MCV 70 fl, Hgb 6 g/dl) and an increased reticulocyte count.[path.upmc.edu]

  • Thalassemia

    On the basis of limited descriptions in the literature, the disease is reported as a mild microcytic anemia with an uncomplicated course.[ncbi.nlm.nih.gov] Note : Thalassemia is a microcytic, hypochromic anemia. Its cause is a genetically based decreased synthesis of one or several globin chains.[lecturio.com] METHODS: The study was done on two adult Thai patients (P1 and P2) who had hypochromic microcytic anemia.[ncbi.nlm.nih.gov]

  • Thalassaemia-Haemoglobin C Disease

    anemia 60 33 hallmark (90%) Very frequent (99-80%) HP:0001935 3 abnormal hemoglobin 60 33 hallmark (90%) Very frequent (99-80%) HP:0011902 4 anemia 60 Very frequent (99-80%[malacards.org] This disease produces a microcytic anemia which is usually mild but which may be severe. Splenomegaly may or may not be present.[pediatrics.aappublications.org] anemia - Splenomegaly[csbg.cnb.csic.es]

  • Thalassemia Minor

    Abstract Iron deficiency anemia (IDA) and thalassemia minor are two of the most common causes of microcytic anemias worldwide.[ncbi.nlm.nih.gov] The peripheral smear showed hypochromic, microcytic anemia with poikilocytes and target cells. Sickling was absent and osmotic fragility was decreased.[jpgmonline.com] A laboratory evaluation revealed a hypochromic microcytic anemia (Hemoglobin 9.8; Hematocrit 28.7; MCV 60; MCH 20.6; Reticulocyte 4.3; Platelets 375; Iron 74 (49-179); TIBC[healio.com]

  • Erythropoietic Protoporphyria

    Microcytic anemia occurs in 20% to 60% of patients. We investigated 178 patients with dominant EPP confirmed by molecular analysis.[ncbi.nlm.nih.gov] anemia, thrombocytopenia, and mild hepatic dysfunction.[ncbi.nlm.nih.gov] This patient presented cutaneous photosensitivity similar to the heterozygous cases, but a higher protoporphyrin accumulation in erythrocytes, microcytic anemia, and early[ncbi.nlm.nih.gov]

  • Hemoglobin E-Thalassemia

    Hb E disease (homozygous Hb E, Hb EE) is also a benign disorder with a mild microcytic anemia (average MCV 62 fl, Hgb 12 g/dl).[path.upmc.edu] In homozygotes, a mild microcytic anemia with prominent target cells exists. Diagnosis of hemoglobin E disorders is by hemoglobin electrophoresis.[merckmanuals.com] anemia.[ PMID 16114182 ] [ PMID 19087310 ] Microarray-based estimation of SNP allele-frequency in pooled DNA using the Langmuir kinetic model. [ PMID 22673309 ] Variation[snpedia.com]

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