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1,725 Possible Causes for Microcytic Anemia, Patient Appears Chronically Ill, Plummer-Vinson Syndrome

  • Iron Deficiency Anemia

    The most used name is Plummer-Vinson syndrome, named after Henry Stanley Plummer (1874–1936) and Porter Paisley Vinson (1890–1959) who were physicians on the staff of the[dx.doi.org] Abstract Iron-refractory iron deficiency anemia (IRIDA) is a rare autosomal recessive disease characterized by congenital hypochromic microcytic anemia, low transferrin saturation[ncbi.nlm.nih.gov] Patients have hypochromic microcytic anemia refractory to oral iron and are only partially responsive to parenteral iron administration.[ncbi.nlm.nih.gov]

  • Anemia of Chronic Disease

    Rare symptoms & signs: -Glossitis or angular cheilitis -Dysphagia due to esophageal web (Plummer-Vinson syndrome) -Koilonychia; "Spoon" fingernails -Pica -soreness of mouth[quizlet.com] Conclusions: CD should be included in the differential diagnosis of microcytic anemia.[doi.org] Iron deficiency anemia (IDA) and anemia of chronic disease (ACD) are the most prevalent, both characterized by hypochromic microcytic anemia and low serum iron (SI).[ncbi.nlm.nih.gov]

  • Iron Deficiency

    Symptoms of iron deficiency include: fatigue dizziness/lightheadedness pallor hair loss twitches irritability weakness pica brittle or grooved nails hair thinning PlummerVinson[en.wikipedia.org] Differentiation from other microcytic anemias Iron deficiency anemia must be differentiated from other microcytic anemias (see table Differential Diagnosis of Microcytic Anemia[merckmanuals.com] This is the Paterson-Brown-Kelly syndrome (or Plummer-Vinson syndrome) and there is an association with oesophageal carcinoma.[patient.info]

    Missing: Patient Appears Chronically Ill
  • Plummer-Vinson Syndrome

    The authors report the case of a 6 year old with Plummer-Vinson syndrome.[ncbi.nlm.nih.gov] Blood tests demonstrate a hypochromic microcytic anemia that is consistent with an iron-deficiency anemia.[en.wikipedia.org] Plummer-Vinson syndrome can be treated effectively with iron supplementation and mechanical dilation.[ncbi.nlm.nih.gov]

    Missing: Patient Appears Chronically Ill
  • Adenocarcinoma of the Colon

    anemia iron deficiency anemia in an elderly male is colon cancer until proven otherwise fecal occult blood test lacks sensitivity and specificity as it only tests for globin[medbullets.com] […] malaise, fatigue, weight loss ) Physical exam palpable mass on rectal exam (if large enough) Evaluation Barium enema X-ray "apple core" lesion Colonoscopy gold standard Labs microcytic[medbullets.com]

    Missing: Plummer-Vinson Syndrome
  • Cecal Adenocarcinoma

    anemia or has a change in bowel habits, do colonoscopy Metastatic workup: CXR, abdominal CT/ultrasound Bone scan, CT head only if lesions suspected Labs: CBC, urinalysis[slideshare.net] (microcytic), /-CEA elevated Radiology /-"apple core" lesion (classic), /-findings of bowel obstruction (air-fluid levels esp. with transition point) Endoscopy /-suspicious[librepathology.org] Investigations Colonoscopy (best), look for synchronous lesions - Alternative: air contrast barium enema (“apple core” lesion) sigmoidoscopy If a patient is FOBT ve, microcytic[slideshare.net]

    Missing: Plummer-Vinson Syndrome
  • Inflammatory Bowel Disease Type 1

    Diagnosis Laboratory data for Crohn disease are nonspecific, as follows: The CBC may show hypochromic microcytic anemia, from iron deficiency due to GI blood loss, or normocytic[emedicine.com] Chronic intestinal bleeding with iron loss (due to bowel inflammation) causes a hypochromic and microcytic anemia with associated hypoferremia and hypoferritinemia; the chronic[doi.org] Multiple pathogenic mechanisms often coexist in anemic patients leading to mixed features anemia.[doi.org]

    Missing: Plummer-Vinson Syndrome
  • Celiac Disease

    , hypochromic anemia and patients characteristically have low serum iron levels, elevated total iron-binding capacity, and low ferritin levels. 24 Measurements of soluble[bloodjournal.org] […] the proximal small intestine and the absorption is dependent upon several factors, including an intact mucosal surface and intestinal acidity. 21 IDA usually manifests as microcytic[bloodjournal.org]

    Missing: Plummer-Vinson Syndrome
  • Gastric Adenocarcinoma

    Adenocarcinoma and lymphoma represent the two most common malignant tumours of the stomach, with both neoplasms being associated with infection by Helicobacter pylori. However, the presence of lymphoma and adenocarcinoma in the same patient is a rare entity with synchronous neoplasms being more common than[…][ncbi.nlm.nih.gov]

    Missing: Plummer-Vinson Syndrome
  • Ayerza Syndrome

    Pickardt Plummer's disease – Henry Stanley Plummer PlummerVinson syndrome (aka Kelly–Patterson syndrome, Paterson–Brown–Kelly syndrome, and Waldenstrom–Kjellberg syndrome[infogalactic.com] , Dyserythropoietic, Congenital, see congenital dyserythropoietic anemia Anemia, hereditary sideroblastic, see X-linked sideroblastic anemia anemia, hypochromic microcytic[mygenomics.com] ) – Henry Stanley Plummer and Porter Paisley Vinson Plyushkin syndrome (aka Diogenes syndrome, Havisham syndrome, and Miss Havisham syndrome)– Stepan Plyushkin, a fictional[ipfs.io]

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