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73 Possible Causes for Micromegakaryocytes

  • Blast Phase

    […] pseudo Pelger-Huet nucleus Megakaryoblastic transformation - peripheral blood: Left: EM showed platelet peroxidase in blasts; middle: high WBC count and high percentage of micromegakaryocytes[pathologyoutlines.com]

  • Transcobalamin 1 Deficiency

    Bone marrow (BM) biopsy showed hypercellular marrow with frequent megaloblasts and few micromegakaryocytes (panel B; original magnification 400, hematoxylin and eosin stain[imagebank.hematology.org]

  • Secondary Myelofibrosis

    […] and elliptocytes Postsplenectomy patient has marked increase in normoblasts and large atypical, partially agranular platelets Cell intermediate between megakaryoblast and micromegakaryocyte[pathologyoutlines.com]

  • Chronic Neutrophilic Leukemia

    There were also significant morphological abnormalities which included neutrophils with few granules, hypersegmented nucleus or Pelger-Heut anomaly, and micromegakaryocytes[ncbi.nlm.nih.gov] […] representing CML at the time of bone marrow biopsy, namely: 1) the vast majority of megakaryocytes showed normal morphology with only rare hypolobated forms, as opposed to the micromegakaryocytes[omicsonline.org] No blast cells or micromegakaryocytes were seen in any of the cases. Importantly, no dysplastic features were noted in the granulocytic series.[nature.com]

  • Greenberg Dysplasia

    Micromegakaryocyte. Ring sideroblasts representing fewer than 15% of nucleated erythroid precursors. Pseudo–Pelger-Huet cell: neutrophil with bilobed nucleus.[emedicine.medscape.com] Micromegakaryocyte. Ring sideroblasts representing fewer than 15% of nucleated erythroid precursors. Pseudo–Pelger-Huet cell: neutrophil with bilobed nucleus. Table 1.[emedicine.medscape.com] Megaloblastoid changes Megakaryocyte Hypolobate or hyperlobate nuclei Multiple, segregated nuclei (“pawn ball” nuclei) Dyssynchronous maturation of nucleus and cytoplasm Micromegakaryocytes[emedicine.medscape.com]

  • Refractory Anemia with Excess Blasts

    Micromegakaryocytes are also seen. Erythropoiesis is essentially normoblastic with minimal dyserythropoiesis. Granulopoiesis is in all stages of maturation.[gpec.ubc.ca] Micromegakaryocytes, large mononuclear forms and multiple separated nuclei are major signs of dysmegakaryocytopoiesis.[atlasgeneticsoncology.org]

  • Myeloid Metaplasia

    […] and elliptocytes Postsplenectomy patient has marked increase in normoblasts and large atypical, partially agranular platelets Cell intermediate between megakaryoblast and micromegakaryocyte[pathologyoutlines.com]

  • Primary Myelofibrosis

    […] and elliptocytes Postsplenectomy patient has marked increase in normoblasts and large atypical, partially agranular platelets Cell intermediate between megakaryoblast and micromegakaryocyte[pathologyoutlines.com] In intensely fibrotic marrows, cellularity may be markedly decreased but megakaryocytes usually remain evident. 274 Giant megakaryocytes and micromegakaryocytes, abnormal[patient-help.com]

  • Chronic Phase of Chronic Myeloid Leukemia

    […] pseudo Pelger-Huet nucleus Megakaryoblastic transformation - peripheral blood: Left: EM showed platelet peroxidase in blasts; middle: high WBC count and high percentage of micromegakaryocytes[pathologyoutlines.com]

  • Xeroderma Pigmentosum

    We also found that there was a statistically significant interaction between the presence of micromegakaryocyte on down regulation of XPC regarding the CT heterozygous genotype[ncbi.nlm.nih.gov]

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