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23 Possible Causes for Microphallus, Small Testicular Volume, Weight Gain

  • Hypogonadotropic Hypogonadism

    gain or weight loss) Long-term (chronic) medical diseases, including chronic inflammation or infections Drug use, such as heroin or use or abuse of prescription opiate medicines[medlineplus.gov] The twins manifested with microphallus, cryptorchidism, and deficient postnatal activation of the hypothalamic-pituitary-gonadal axis, findings consistent with IHH.[ncbi.nlm.nih.gov] Cryptorchid or maldescended testes and small testicular volume are clinical hallmarks of congenital hypogonadotropic hypogonadism (CHH) [ 1 ].[ijpeonline.biomedcentral.com]

  • Klinefelter Syndrome

    Beyond single case reports, data are not available for 48,XXXY; however, microphallus is described in case reports, ( 10 ) and it is predicted that mean phallus length would[ncbi.nlm.nih.gov] They concluded that the decline in serum testosterone may be related to the small testicular volume and Leydig cell loss near the scars after the procedures.[web.archive.org] gain, especially on the stomach or trunk tiredness and fatigue small penis disproportionately long arms and legs compared to the length of the body taller than average height[betterhealth.vic.gov.au]

  • Hypogonadism

    gain or weight loss) Long-term (chronic) medical diseases, including chronic inflammation or infections Drug use, such as heroin or use or abuse of prescription opiate medicines[medlineplus.gov] Other manifestations include microphallus, cryptorchidism, midline defects, and unilateral kidney agenesis.[msdmanuals.com] […] testes – volume typically 3 Lack of secondary sexual characteristics Most common cause is Klinefelter syndrome Postpubertal hypogonadism Sexual – decreased libido, erectile[arupconsult.com]

  • ROHHAD Syndrome

    […] age of hypopituitarism onset.1,2,4,6,11,19,29, 33 One of the primary sources of diagnostic information relevant to hypotalamo-pituitary abnormalities is family history of microphallus[mafiadoc.com] Children with ROHHAD typically present after 1.5 years of age with rapid weight gain as the initial sign.[ncbi.nlm.nih.gov] CASE CHARACTERISTICS: A 7-year-old girl with ROHHAD syndrome who had central hypoventilation, rapid weight gain, multiple cardiac arrests and hyperprolactinemia.[ncbi.nlm.nih.gov]

  • Anorchia

    Before puberty induction both boys had a similar weight and height. During puberty, a slightly faster weight and height gain was observed in the affected twin.[ncbi.nlm.nih.gov] Physical examination may reveal microphallus or normal external male genitalia with bilateral or unilateral palpable intrascrotal or inguinal masses or no palpable masses.[symptoma.com] Testicles are “born” small and grow in size during puberty and later adulthood before losing some volume in later age.[drelist.com]

  • Kallmann Syndrome Type 4

    Rapid weight gain continues into adulthood; stature remains short and may be caused by growth hormone deficiency.[msdmanuals.com] They include microphallus (up to 65%), cryptorchidism (up to 73%), hearing loss ( 30%), renal agenesis, synkinesis (the involuntary movement of one hand when the other is[clinicaladvisor.com] Cryptorchid or maldescended testes and small testicular volume are clinical hallmarks of congenital hypogonadotropic hypogonadism (CHH) [ 1 ].[ijpeonline.biomedcentral.com]

  • Hypogonadotropic Hypogonadism Type 18

    gain or weight loss) Chronic medical diseases, including chronic inflammation or infections Certain medical conditions, such as iron overload[jeanbrownresearch.com] As a result, he had a full-skin exam and was found to have a microphallus, undescended testes, and minimal pubic hair distribution. He had a normal sense of smell.[omicsonline.org] The clinical phenotype of our patients mirrored the severity of their hormonal deficiency with small prepubertal testicular volume and underdeveloped external genitalia.[journals.plos.org]

  • Kallmann Syndrome Type 3

    As a result, he had a full-skin exam and was found to have a microphallus, undescended testes, and minimal pubic hair distribution. He had a normal sense of smell.[omicsonline.org] Mean testicular volumes of HH patients were measured at the time of the diagnosis (solid circles) and at participation in the current study (small line).[journals.plos.org] Rapid weight gain continues into adulthood; stature remains short and may be caused by growth hormone deficiency.[msdmanuals.com]

  • Hypogonadotropic Hypogonadism Type 8

    The first patient (A) suffered from significant secondary symptoms, i.e. weight gain and skeletal pain, which had caused him to seek medical assistance.[thieme-connect.com] As a result, he had a full-skin exam and was found to have a microphallus, undescended testes, and minimal pubic hair distribution. He had a normal sense of smell.[omicsonline.org] When the deficit is more severe and testicular volume is very small, FSH must be added [ 1 ].[em-consulte.com]

  • Primary Male Hypogonadism

    Other manifestations include microphallus, cryptorchidism, midline defects, and unilateral kidney agenesis.[merckmanuals.com] Lower than expected stage of puberty Small testicular volume Features of pituitary disease (e.g visual field defects) How should male hypogonadism be investigated?[brainscape.com] Typical symptoms include a low sex drive, erectile dysfunction, infertility, fatigue, weight gain and enlarged breasts.[nyhq.org]

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