Mild Clinical Course: Causes & Reasons

Warning: Do not use in emergencies, if pregnant, if under 18, or as a substitute for a doctor’s advice or diagnosis. Learn more

Possible Causes for Mild Clinical Course

Infectious Mononucleosis

Clinical course A mild IM attack may resolve in days, but it is more usual for the disease to last for 2–3 weeks, followed by a period of lethargy before complete recovery [onlinelibrary.wiley.com]

Limb-Girdle Muscular Dystrophy Type 1G

Early childhood onset of LGMD2I usually indicates a severe clinical course with affected individuals needing a wheelchair by the second decade. [rarediseases.org]

LGMD2I (fukutin-related proteinopathy) This form of LGMD may range from mild to severe. [rarediseases.org]

Erythema Infectiosum

CONCLUSION: The results of this study confirm the presence of EI (the fifth disease) in our area with a mild course in the majority of patients. [ncbi.nlm.nih.gov]

Since the diagnosis of EI is usually based on clinical findings, continuing medical education of primary health care pediatricians is essential for reducing the number of [ncbi.nlm.nih.gov]

Rubella

Rubella is transmitted via airborne droplets and has a mild clinical course. [amboss.com]

Despite the complicated clinical course, the child survived. [ncbi.nlm.nih.gov]

At follow-up he has a normal pulmonary examination, mild hyperinflation only on his chest radiograph, normal immunology and normal respiratory reactance and resistance. [ncbi.nlm.nih.gov]

Dysthymic Disorder

OBJECTIVE: The purpose of this study was to assess the duration of periods of euthymia in patients with dysthymia. METHOD: All patients with dysthymia who came to the Center for Anxiety and Depression over a 10-month period (N = 22) were interviewed by the author regarding the duration of their euthymic[…] [ncbi.nlm.nih.gov]

Vasovagal Syncope

What is vasovagal syncope? Vasovagal syncope, also called a “common faint”, is a brief loss of consciousness due to a vasovagal reflex. The vasovagal reflex is the combination of: sympathetic withdrawal causing vasodilation (vaso), and parasympathetic (vagal) disinhibition causing bradycardia. It is thus a combination[…] [syncopedia.org]

Pityriasis Circinata

PITYRIASIS ROTUNDA. (PITYRIASIS CIRCINATA) I SARKANY et al. Br J Dermatol. 1964 May. No abstract available Similar articles An update on pityriasis rosea and other similar childhood exanthems. Browning JC. Browning JC. Curr Opin Pediatr. 2009 Aug;21(4):481-5. doi: 10.1097/MOP.0b013e32832db96e. Curr Opin Pediatr. 2009. PMID:[…] [pubmed.ncbi.nlm.nih.gov]

Vasomotor Rhinitis

OBJECTIVES: Description of the ultrastructural localization of nitric oxide synthase in the blood vessels of the nasal respiratory mucosa in patients with vasomotor rhinitis. STUDY DESIGN: This research was conducted on seven patients--men and women, ages 20 to 45 years--suffering from vasomotor rhinitis and who[…] [ncbi.nlm.nih.gov]

Fort Bragg Fever

[…] pretibial [ pre-tib´e-al ] in front of the tibia. pretibial fever leptospirosis due to Leptospira interrogans serogroup autumnalis, marked by a rash on the pretibial region, with lumbar and postorbital pain, malaise, nasal inflammation, and fever. Also known as Fort Bragg fever because it was observed at Fort Bragg,[…] [medical-dictionary.thefreedictionary.com]

Pityriasis Alba

Pityriasis alba is a common skin disorder of patches of light-colored (hypopigmented) areas. Causes The cause is unknown but may be linked to atopic dermatitis (eczema). The disorder is most common in children and teens. It is more noticeable in children with dark skin. Symptoms The problem areas on the skin[…] [mountsinai.org]

Balantidiasis

[…] close Please confirm that you would like to log out of Medscape. If you log out, you will be required to enter your username and password the next time you visit. Log out Cancel Updated: Nov 28, 2018 Author: Valda M Chijide, MD; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD more... Overview Background[…] [emedicine.com]

Metaldehyde Poisoning

Although the toxicity from metaldehyde is largely mild, the clinical course of metaldehyde poisoning may be rapidly deteriorating and fatal on rare occasions. [ncbi.nlm.nih.gov]

Autosomal Recessive Osteopetrosis Type 8

One OPTA2 patient displaying life-threatening symptoms died, and the OPTB4 patient presenting a relatively mild clinical course survived. [pubmed.ncbi.nlm.nih.gov]

Cennamo-Gangemi-Magli Syndrome

Chondrodysplasia punctata with a mild clinical course. J Inherit Metab Dis 1994;17:60–6. CAS PubMed Google Scholar Begeer JH, Scholte FA, van Essen AJ. [nature.com]

Macrocephaly Type Fryns

Developmental delay ranging from relatively mild impairment to severe intellectual disability has been reported in individuals with clinically diagnosed Fryns syndrome. [ncbi.nlm.nih.gov]

Due to impaired survival, the developmental course is not known for those with Fryns syndrome caused by PIGN pathogenic variants. [ncbi.nlm.nih.gov]

Intrapartum Uterine Rupture

Mild clinical course despite complete uterine rupture was presumably because of adhesion of the ovaries and intestines to the rupture site. Related Information [obgyn.onlinelibrary.wiley.com]

Isolated Complex I Deficiency

clinical course in this patient contrasts with nearly all other cases of severe COX assembly defects that are usually fatal early in life, and underscores the marked tissue-specific [forskning.ku.dk]

Two sisters, patients 2 and 3, who presented at 6-7 months of age with progressive muscle weakness and delayed motor development, and have since showed a mild clinical course [gu.se]

LS-SURF-1 patients had a more severe clinical course. CONCLUSION: The MR pattern in LS SURF-1 patients is characteristic. [ajnr.org]

Autosomal Recessive Osteopetrosis Type 7

One OPTA2 patient displaying life-threatening symptoms died, and the OPTB4 patient presenting a relatively mild clinical course survived. [wwww.unboundmedicine.com]

Cytochrome B5 Reductase Deficiency

Clinically, methemoglobinemia has a variable course (see Presentation). Because of the nonspecificity of the clinical findings, mild cases may go undiagnosed. [emedicine.medscape.com]

Canavan Disease

Possible genotype-phenotype correlations in children with mild clinical course of Canavan disease. [ncbi.nlm.nih.gov]

Alpha Type Methemoglobinemia

Clinically, methemoglobinemia has a variable course (see Presentation). Because of the nonspecificity of the clinical findings, mild cases may go undiagnosed. [emedicine.medscape.com]

Simpson-Golabi-Behmel Syndrome Type 2

Clinical aspects Wide spectrum of clinical manifestations from mild course with survival to adulthood to severe course with early neonatal death. [accessanesthesiology.mhmedical.com]

Autosomal Recessive Spastic Ataxia with Leukoencephalopathy

clinical course’. [neurologyindia.com]

Megalencephaly and leukodystrophy with mild clinical course: A report on 12 new cases. Brain Dev 1998;20:142-53. 7. [annalsofian.org]

Once a child becomes nonambulatory, the clinical course may remain stable for several years. Swallowing difficulties and optic atrophy develop late in the disease. [leukodystrophyresourceresearch.org]

Alexander Disease

We report a 6-year-old Indian boy with infantile-onset Alexander disease, who has an unusually mild clinical course and a de novo p.Leu359Val mutation in the glial fibrillary [ncbi.nlm.nih.gov]

Leukoencephalopathy with swelling and a discrepantly mild clinical course in eight children. [ajnr.org]

The clinical symptoms were qualitatively the same in both severe and mild cases. [ajnr.org]

Dennis-Fairhurst-Moore Syndrome

Chondrodysplasia punctata with a mild clinical course. J Inherit Metab Dis 1994;17:60–6. CAS PubMed Google Scholar Begeer JH, Scholte FA, van Essen AJ. [nature.com]

Congenital Aplastic Anemia

Both had mild clinical courses and prolonged response to androgen therapy, one had persistent remission for 3 years after therapy. [annals.org]

Prognosis Aplastic anaemia has a varied clinical course; some patients have mild symptoms that necessitate little or no therapy, whereas others present with life-threatening [patient.info]

Galactosialidosis

clinical course. [link.springer.com]

clinical courses. [dx.doi.org]

VAT (Finland) References Andria G, Striscuiglio P, Pontarelli G, Sly WS, Dodson WE (1981) Infantile neuraminidase and β-galactosidase deficiencies (galactosialidosis) with mild [link.springer.com]

Löffler Syndrome

Abstract In 1932 Löffler (9) described a transitory pulmonary lesion associated with a high degree of eosinophilia, having a mild clinical course. [pubs.rsna.org]

Fibrodysplasia Ossificans Progressiva

clinical course. [ncbi.nlm.nih.gov]

The clinical symptoms were similar to those reported previously: the delayed onset with a slower and mild clinical course and little finger camptodactyly. [ncbi.nlm.nih.gov]

A patient from Japan with an ACVR1 gene mutation had normal development until age 17 years and a mild clinical course. [11] The resultant mutations were interpreted to result [emedicine.medscape.com]

Myopathic Carnitine Deficiency

Proximal; Symmetric; Legs > Arms; Paraspinal Course: Increases with age Other muscle features Muscle atrophy: May be generalized Fatigue with exercise Rhabdomyolysis 9: [neuromuscular.wustl.edu]

Onset Age: Adult; Range 27 to 72; Mean 5th decade Signs: Fatigue; Movement disorder; Seizure Weakness (65%) Severity: Usually mild; Occasionally severe or none Distribution [neuromuscular.wustl.edu]

[…] disease Chorein: Autosomal-recessive Chorea-Acanthocytosis Muscle location Type II muscle fibers Intracellular: Sarcoplasmic reticulum Staining is absent in McLeod myopathy Clinical [neuromuscular.wustl.edu]