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20 Possible Causes for Mild Clinical Course, Virus Associated Hemophagocytic Syndrome

  • Erythema Infectiosum

    Virus-associated hemophagocytic syndrome.[cmr.asm.org] CONCLUSION: The results of this study confirm the presence of EI (the fifth disease) in our area with a mild course in the majority of patients.[ncbi.nlm.nih.gov] Virus-associated hemophagocytic syndrome: a benign histiocytic proliferation distinct from malignant histiocytosis. Cancer 44 : 993 -1002. Rodis, J. F., A. F.[cmr.asm.org]

  • Infectious Mononucleosis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis. Am J Hematol. 1996 Oct. 53(2):111-5. [Medline].[emedicine.medscape.com] Epstein-Barr virus-induced infectious mononucleosis after two separate episodes of virus-associated hemophagocytic syndrome. Intern Med. 2009. 48(13):1169-73. [Medline].[emedicine.medscape.com]

  • Sickle Cell Disease

    HbS/HbE syndrome : very rare and generally very mild clinical course. Rare combinations of HbS with HbD Los Angeles, HbO Arab, G-Philadelphia, among others.[patient.info] Some individuals experience morbidity and mortality in early childhood, while others have a relatively mild course, and normal or near normal life expectancy.[ncbi.nlm.nih.gov] HbS/HbE syndrome: double heterozygote for HbS and HbE, very rare and generally very mild clinical course.[doi.org]

  • Hydroa Vacciniforme

    In contrast out of 11 severe patients in this study, 6 had evidence of chronic EBV infection, 5 had hypersensitivity to mosquito bites, 4 had virus-associated hemophagocytic[en.wikipedia.org] Three patients with severe HV (cases 21, 28, and 29) had repetitive episodes of mild to moderate vesiculopapular eruptions mimicking HV in the clinical course of EBV-associated[jamanetwork.com] syndrome . 6 of the severe group had natural killer-cell lymphocytosis in the peripheral blood.[wikidoc.org]

  • Viral Pneumonia

    Virus-associated hemophagocytic syndrome may play an important role in development of multiorgan failure and ensuing death in H1N1 infection. [28] For more information on[emedicine.com] clinical course.[ncbi.nlm.nih.gov] Virus-associated hemophagocytic syndrome as a major contributor to death in patients with 2009 influenza A (H1N1) infection. Crit Care. 2011 Mar 2. 15(2):R80. [Medline].[emedicine.medscape.com]

  • Hydroa Vacciniforme-Like Lymphoma

    In contrast out of 11 severe patients in this study, 6 had evidence of chronic EBV infection, 5 had hypersensitivity to mosquito bites, 4 had virus-associated hemophagocytic[en.wikipedia.org] The clinical course of EBV-associated HLH varies from mild to severe or fatal.[frontiersin.org] Five patients with severe HV died of EBV-associated NK/T-cell lymphomas or hemophagocytic syndrome 2 to 14 years after onset.)[clinicaladvisor.com]

  • Hepatosplenomegaly

    T-cell lymphoma and the virus-associated hemophagocytic syndrome. Am J Clin Pathol. 1991; 97 :189–194. [ PubMed ] 16.[ncbi.nlm.nih.gov] However, I still think based on the clinical picture, it would have been inappropriate to come to a provisional diagnosis of malaria, as there was no jaundice, the rapid course[nrsmedic.blogspot.com] Craig F, Clare N, Sklar J, Banks P (1991) T-cell lymphoma and the virus-associated hemophagocytic syndrome. Am J Clin Pathol 97: 189–194. View Article Google Scholar 16.[journals.plos.org]

  • Infectious Mononucleosis Hepatitis

    Severe chronic active Epstein-Barr virus infection accompanied by virus-associated hemophagocytic syndrome, cerebellar ataxia and encephalitis.[emedicine.medscape.com] Close monitoring during the clinical course of the illness is recommended, as a minority of patients may develop acute liver failure or progress to CAEBV.[smj.org.sg] Epstein-Barr virus-associated hemophagocytic syndrome and fatal infectious mononucleosis. Am J Hematol. 1996 Oct. 53(2):111-5. [Medline].[emedicine.medscape.com]

  • Autoimmune Hepatitis

    Virus-, drug- and lymphoma-associated hemophagocytic syndrome (HPS) was ruled out. Therefore, the patient was diagnosed with autoimmune-associated HPS (AAHS).[ncbi.nlm.nih.gov] The ulcerative colitis typically involves a majority of the colon, but often has a relatively mild clinical course.[dx.doi.org]

  • Erythema Multiforme

    Matsumoto YNaniwa DBanno SSugiura Y The efficacy of therapeutic plasmapheresis for the treatment of fatal hemophagocytic syndrome: two case reports.[jamanetwork.com] Because of the distinct morphology, mild disease course, and potentially important clinical implications regarding treatment, we propose a revision of the nomenclature system[ncbi.nlm.nih.gov] HSV‐induced EM Antiviral suppressive therapy (treatment after appearance of HSV‐induced EM does not affect clinical course) Mycoplasma pneumoniae –associated EM Might include[onlinelibrary.wiley.com]

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