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360 Possible Causes for Mild Hyperkeratosis

  • Insect Bite

    Chronic spongiotic dermatitis The spongiosis is mild to absent but there is pronounced irregular acanthosis, hyperkeratosis, and parakeratosis (fig 8D).[] (D) Chronic spongiotic dermatitis showing irregular acanthosis, hyperkeratosis, and parakeratosis.[] The degree of spongiosis and exocytosis of the inflammatory cells is mild to moderate, and compared with acute spongiotic dermatitis there is irregular acanthosis and parakeratosis[]

  • Ichthyosis Vulgaris

    Abstract Ichthyosis vulgaris is an autosomal dominant disorder of keratinization characterized by mild hyperkeratosis and reduced or absent keratohyalin granules in the epidermis[] Ichthyosis vulgaris is characterized histologically by absent or reduced keratohyalin granules in the epidermis and mild hyperkeratosis.[] The palms and soles appear hyperlinear with accentuated skin markings due to mild hyperkeratosis. Cracking and painful fissures of the heels are common.[]

  • Insulin Resistance

    Fig. 5 Biopsy from the neck of a patient with acanthosis nigricans, showing histological features of orthokeratotic hyperkeratosis, mild acanthosis, and papillomatosis (hematoxylin[] , acanthosis, and mild papillomatosis (see Fig. 5 ).[] One study demonstrated that the most frequent finding was hyperkeratosis in 100%, followed by papillomatosis in 90% of biopsies; a less frequent finding was irregular acanthosis[]

  • Dermatitis

    Mild dermatitis typically starts in the finger webs and the knuckle areas of the hands. In moderate cases the area enlarges to the back of the hands and the fingers.[] Morphologically the clinical features in acute cases range from redness, oedema, and vesiculation, to thickening of the skin, hyperkeratosis, desquamation, and fissuring in[]

  • Acanthosis Nigricans

    Biopsy of the skin showed hyperkeratosis, papillomatosis, hyperpigmentation of the basal layer, and mild acanthosis.[] Histopathologically, all forms of AN demonstrate epidermal hyperkeratosis, papillomatosis and minimal to mild acanthosis.[] The valleys between papillae show mild acanthosis and are filled with keratotic material.[]

  • Epidermodysplasia Verruciformis

    Skin biopsy shows verruca plana-like lesions with mild hyperkeratosis, hypergranulosis and acanthosis of the epidermis.[] hyperkeratosis and acanthosis GENETICS: GENETICS Autosomal recessive disease Caused by an inactivating HP mutation in either the EVER1 or EVER2 genes Located adjacent to[] […] premalignant and malignant lesions Most characteristic findings are seen within the epidermis Classic histological manifestation of EV is a verruca plana -like lesion with mild[]

  • Psoriasis

    Histologic findings of nail psoriasis include mild-to-moderate hyperkeratosis, hypergranulosis, serum globules and hemorrhage in the corneum layer, papillomatous epidermal[] […] will require initial anesthesia block. 34 In mild psoriatic disease, where 1 or 2 plaques are resistant to topical treatments, for example, intralesional steroids may play[] The decision of whether to use anesthesia depends on the patient; however, injecting the deep proximal nail fold or the nail bed to target subungual hyperkeratosis or onycholysis[]

  • Pityriasis Circinata

    We showed that hyperkeratosis, acanthosis, pappillomatosis, intraepidermal vesicles, RBCs in dermis and mild vasculitis like changes were more common in biopsies from herald[] Histologically, findings are often subtle, but hyperkeratosis, a thinned granular layer, pigmented basal layer, and mild perivascular lymphocytic infiltrate are commonly reported[]

  • Confluent and Reticulated Papillomatosis

    Microscopic Histopathology There was mild hyperkeratosis, papillomatosis, and focal acanthosis present between elongated dermal papillae.[] The histology showed epidermal papillomatosis and mild acanthosis with a marked hyperkeratosis.[] Histological examination of a skin biopsy taken from the abdomen showed hyperkeratosis, papillomatosis and mild superficial perivascular lymphocytic infiltrate (Fig. 2).[]

  • Cryptogenic Organizing Pneumonia

    Figure 3: Mild hyperkeratosis and mixed perivascular inflammatory infiltrate in the upper dermis (H and E original magnification, 100) Click here to view Since its first description[] hyperkeratosis, focal parakeratosis and epidermal spongiosis with superficial mononuclear, lymphohistiocytic perivascular inflammatory infiltrate in the dermis. [4], [5][] […] induction of inflammation. [4], [5] Despite a distinctive clinical morphology, skin lesions of erythema gyratum repens have non-specific histologic findings with acanthosis, mild[]

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