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54 Possible Causes for Mild Pulmonary Hypertension, Thickening of the Mitral Valve Leaflets

  • Mucopolysaccharidosis

    RATIONALE: Mucopolysaccharidosis type VI (MPS VI) or Maroteaux-Lamy syndrome is produced by the deficiency of the enzyme arylsulfatase B, responsible for the hydrolysis of N-acetyl-D-galactosamine, chondroitin sulfate, and dermatan sulfate. PATIENT CONCERNS: A 3-year-old male with Moroccan origins is the index[…][ncbi.nlm.nih.gov]

  • Mucopolysaccharidosis 1 H-S

    Progressive thickening and stiffening of the valve leaflets can lead to mitral and aortic regurgitation, which may become hemodynamically significant in the later stages of[ncbi.nlm.nih.gov]

  • Mitral Valve Prolapse

    […] of even mild pulmonary hypertension can be an early sign of failure to compensate for chronic MR, early MV repair should also be considered in patients with mild to moderate[circ.ahajournals.org] Two groups of patients were compared: those with thickening of the mitral-valve leaflets and redundancy (designated the classic form; n 319) and those without leaflet thickening[oadoi.org] One athlete had mild pulmonary hypertension. Mitral valve prolapse was found in 29 athletes (20%; 4 with mild regurgitation).[ncbi.nlm.nih.gov]

  • Mitral Valve Stenosis

    In severe stenosis the back pressure can extend right back through all the blood vessels in the lungs to the right ventricle of the heart (pulmonary hypertension).[patient.info] Mitral stenosis is characterized by thickening and immobility of the mitral valve leaflets.[symptoma.com] Once more than mild symptoms exist or once asymptomatic pulmonary hypertension occurs, mechanical relief of MS is indicated.[doi.org]

  • Lutembacher Syndrome

    Large Ostium Secondum atrial septal defect With Left To Right Shunt; Mild pulmonary arterial hypertension.[ncbi.nlm.nih.gov] Note the thickened, narrowed, and calcified mitral valve apparatus and doming of the anterior leaflet of the mitral valve.[emedicine.medscape.com] […] of Lutembacher's syndrome suggestive of incomplete right bundle branch block with left atrial enlargement 2D-Echocardiography [Figures 2 and 3 ] Moderate Mitral stenosis; Mild[ncbi.nlm.nih.gov]

  • Mitral Valve Disease

    Another potential complication of mitral regurgitation is pulmonary hypertension . Treatment for mild mitral regurgitation may include anticoagulation medication .[heart.org] At surgery, nodular thickening of both valves and fusion of the posterior leaflet of the mitral valve were seen.[ncbi.nlm.nih.gov] If symptoms are more than mild or if there is evidence of pulmonary hypertension, mechanical intervention is warranted and delaying intervention worsens prognosis. 3 Unlike[aafp.org]

  • Congenital Mitral Stenosis

    In older patients the development of atrial fibrillation often accompanies the onset of pulmonary hypertension.[bcm.edu] Definition (CSP) rheumatic disease causing diffuse thickening of the mitral valve leaflets by fibrous tissue or calcific deposits.[fpnotebook.com] Pulmonary arterial vasoconstriction (reactive component) 14 Indications for Mitral Valve Operation Severe symptoms signs of important pulmonary venous hypertension are indications[powershow.com]

  • Mitral Valve Insufficiency

    Another potential complication of mitral regurgitation is pulmonary hypertension . Treatment for mild mitral regurgitation may include anticoagulation medication .[heart.org] Abstract Mitral valve insufficiency in rheumatic heart disease is often due to retracted posterior chordae and posterior leaflet thickening.[ncbi.nlm.nih.gov] MR and no evidence of LV enlargement, LV dysfunction, or pulmonary hypertension – Yearly observation; serial TTE is not indicated Patients with moderate MR – Yearly TTE Asymptomatic[emedicine.medscape.com]

  • Hypertrophic Cardiomyopathy

    […] can lead to tachycardia and systemic arterial hypertension as well as unwanted catecholamine release.[anesthesiology.pubs.asahq.org] […] of an anomalous papillary muscle [arrow] onto the ventricular surface of the anterior mitral leaflet).[doi.org] The mitral valve leaflets often appear enlarged relative to the cavity of the left ventricle.[doi.org]

  • Infective Endocarditis

    pulmonary hypertension.[ncbi.nlm.nih.gov] […] history of endocarditis history of illegal drug use mitral valve prolapse and valve regurgitation (leaking) and/or thickened valve leaflets The risk of infective endocarditis[healthline.com] It caused severe mitral stenosis and mild pulmonary hypertension. Systolic function was normal for both ventricles, and no masses were attached to the other valves.[ncbi.nlm.nih.gov]

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