Mild Weakness: Causes & Reasons

Possible Causes for Mild Weakness

His examination demonstrated a muscular man with mild weakness (4/5) of iliopsoas muscles. [ncbi.nlm.nih.gov]

Neurological examination showed normal Mini-Mental State Examination score (27/30), calf pseudohypertrophy, mild symmetrical weakness in proximal muscles in the lower limbs [scielo.br]

Chest physiotherapy and manually-assisted cough (MAC) may be sufficient only for patients with mild exspiratory muscle weakness. [ncbi.nlm.nih.gov]

Central Core Disease

She had mild facial weakness and mild weakness of neck flexion (MRC 4/5); upper limb power was normal. [doi.org]

She was hypotonic with a mild degree of facial weakness. [doi.org]

On examination at 42 years of age, she was found to have facial weakness and mild weakness of the hip adductors. [doi.org]

Distal Myopathy Type 3

The degree of muscle weakness involved can range from mild to severe. The cause remains unknown. [mda.org]

Mild proximal weakness develops more than ten years after the onset of the disease. [orpha.net]

Those with only one defective gene experience mild weakness of the tibial leg muscles (front of the calf) sometime after age 40. [mda.org]

Congenital Fiber-Type Disproportion Myopathy

Typically, there was proximal limb girdle weakness, prominent weakness of neck flexion and ankle dorsiflexion, mild facial weakness, and mild ptosis. [research-repository.uwa.edu.au]

Mild facial weakness and ptosis, and winged scapula were common. Intellectual function was normal. [pediatricneurologybriefs.com]

Neck muscle weakness and extensor contractures were common. Most had generalized amyotrophy, proximal limb weakness, and a waddling gait. [pediatricneurologybriefs.com]

Multicore Myopathy with External Ophthalmoplegia

A 10-y-old girl is presented who suffered mild muscular weakness and exercise intolerance from the age of 1 y onwards, with progression appearing from the age of about 8 y [ncbi.nlm.nih.gov]

mild truncal andproximal limb weakness. [docslide.com.br]

[…] stature Genitourinary Internal Genitalia Female: hypogonadotropic hypogonadism Neurologic Central Nervous System: mental retardation, severe small sella Muscle Soft Tissue: mild [malacards.org]

X-linked Distal Spinal Muscular Atrophy Type 3

[…] of distal muscles of hands and feet with normal deep tendon reflexes or absent ankle reflexes and minimal or no sensory loss, sometimes mild proximal weakness in the legs [orpha.net]

In some people, the symptoms start when they are teens or young adults, and these patients have mild weakness and continue to be able to walk. [childneurologyfoundation.org]

weakness. [ipfs.io]

Neonatal Adrenoleukodystrophy

Carriers of X-linked ALD may experience mild symptoms, including weakness of the legs, loss of coordination, excessive muscle tone, urinary problems, and numbness or tingling [healthinhandorganics.com]

Myotonia permanens

They may also develop mild, permanent muscle weakness over time. This muscle weakness is not seen in people with TD. [mda.org]

Diamox Myotonia Fluctuans Provokes stiffness, NO weakness K+ ? Mild, Varies ? Diamox, K+ wasting diuretics Myotonia Permanens Provokes severe myotonia ? K+ ? [hkpp.org]

Individuals with mild myotonic dystrophy type I may have cataracts and baldness as their only symptoms.[3] It may also be seen as mild weakness and difficulty relaxing typically [wiki.ubc.ca]

Fingerprint Body Myopathy

These cases were characterized by early onset of symptoms, mild proximal weakness, hyporeflexia or areflexia, normal serum muscle enzyme levels, short duration of motor unit [archneur.jamanetwork.com]

Examination demonstrated a hyp-ractive boy with diffuse, mild weakness and reduced muscle bulk. [docslide.com.br]

Another patient (Patient No. 7) showed mild right proximal lower extremity weakness with hip pain. [synapse.koreamed.org]

Chudley-Rozdilsky Syndrome

Intellectual disability-myopathy-short stature-endocrine defect syndrome is a rare congenital myopathy syndrome characterized by nonprogressive myopathy (manifesting with mild [malacards.org]

[…] generalized weakness, short stature, musculoskeletal deformities, facial anomalies, sexual infantilism, and radiologic evidence of pituitary hypoplasia. [onlinelibrary.wiley.com]

[…] facial and generalized weakness, bilateral ptosis, and severe lumbar lordosis), severe intellectual disability, short stature, and sexual infantilism (due to hypogonadotropic [malacards.org]

Distal Spinal Muscular Atrophy Type 3

[…] of distal muscles of hands and feet with normal deep tendon reflexes or absent ankle reflexes and minimal or no sensory loss, sometimes mild proximal weakness in the legs [orpha.net]

In SMA-3 there is often gait difficulty and proximal weakness. In SMA-4 there is mild weakness occurring in adulthood. [now.aapmr.org]

weakness. [ipfs.io]

Erb Muscular Dystrophy

Affected individuals develop weakness of the lower limbs that may be mild or severe. Weakness of facial muscles may also occur. [rarediseases.org]

Symptoms can range from mild skeletal muscle weakness or cardiac involvement to severe weakness or cardiac effects and can begin in childhood or adulthood. [mda.org]

Clinical Weakness Onset age: 6 to 58 years Course: Progressive; Mild to Severe Distribution Proximal Asymmetric Often Arms & Legs Legs > Arms Shoulder abduction; Elbow flexion [neuromuscular.wustl.edu]

Adult Spinal Muscular Atrophy

In adults, normal life expectancy is achieved, as only mild weakness may be encountered. The diagnosis rests on confirming genetic mutations. [symptoma.com]

The clinical spectrum ranges from early infant death in severe type I to normal adult life with only mild weakness in adult type IV. [nxgenmdx.com]

These children show signs of clumsiness, difficulty walking, mild muscle weakness, and may be developmentally delayed. These children live long into their adult years. [texaschildrens.org]

Andersen-Tawil Syndrome

Sometimes, the patient’s muscles are weak and heavy, but other times, the muscles are completely paralyzed. There also tends to be mild weakness between attacks. [periodicparalysis.org]

From 2010 to 2013 he had only one episode of weakness that was mild and related to a physical effort. In May 2013 he suddenly developed many episodes of weakness. [nature.com]

Reflexes may be absent or diminished during the episodes of weakness. Mild persistent weakness is also fairly common. [neurologyindia.com]

Facial Palsy

weakness to complete paralysis. [flexikon.doccheck.com]

Symptoms Signs and symptoms of Bell's palsy come on suddenly and may include: Rapid onset of mild weakness to total paralysis on one side of your face — occurring within hours [mayoclinic.org]

Sometimes you have a little pain behind your ear before the weakness starts. The weakness may range from mild weakness to a total inability to move, called paralysis. [msdmanuals.com]

Congenital Myopathy with Excess of Thin Filaments

[…] facial weakness; skeletal anomalies; risk for MH in those with RYR1 mutations Multi/minicore myopathy AR AD/AR AR AD AR Selenoprotein N1/( SEPN1 ) Ryanodine receptor ( RYR1 [mhmedical.com]

[…] of hip girdle and axial muscles Mild facial weakness, extraocular muscles spared, no cardiac involvment Bulbar and respiratory involvement uncommon Histology: central cores [quizlet.com]

In contrast, missense mutations result in mild to moderate weakness, contractures, and mild skeletal deformities with life into teenage years. [emedicine.medscape.com]

Transient Neonatal Myasthenia Gravis

Class II: Mild weakness of any muscle group is possible as well as ocular muscle weakness of any degree. [intechopen.com]

Because weakness is a common symptom of many other disorders, the diagnosis is often missed in people who experience mild weakness or in those individuals whose weakness is [daviddarling.info]

Weakness is a symptom of several other disorders; a diagnosis of Myasthenia Gravis is often missed in persons with mild weakness, or in persons who experience weakness in [disabled-world.com]

Limb-Girdle Muscular Dystrophy Type 2C

There was proximal weakness in both upper and lower extremities. There was also mild weakness of ankle dorsiflexion and plantar flexion. [omicsonline.org]

Patients have mild-to-moderate proximal weakness with slow-to-moderate progression. Exercise-induced cramps may be present. Calf hypertrophy affects some patients. [checkorphan.org]

[…] with severe cardiomyopathy to a much more benign adult onset with mild weakness and slow progression. [now.aapmr.org]

Limb-Girdle Muscular Dystrophy Type 1E

Fukutin related protein LGMD 2J Onset 1 st to 3 rd decade, proximal lower limb weakness, mild distal weakness, progressive weakness causes loss of ambulation Titin LMGD 2K [jcdr.net]

Patients have mild-to-moderate proximal weakness with slow-to-moderate progression. Exercise-induced cramps may be present. Calf hypertrophy affects some patients. [checkorphan.org]

[…] with severe cardiomyopathy to a much more benign adult onset with mild weakness and slow progression. [now.aapmr.org]

Rigid Spine Syndrome

[…] facial weakness; skeletal anomalies; risk for MH in those with RYR1 mutations Multi/minicore myopathy AR AD/AR AR AD AR Selenoprotein N1/( SEPN1 ) Ryanodine receptor ( RYR1 [mhmedical.com]

We report a Chinese man with RSS and mild proximal lower limb weakness since 15 years old. [neurology-asia.org]

[…] axial and proximal muscle weakness, flexion contractures of the neck and spine, scoliosis, and joint contractures. [jamanetwork.com]

Autosomal Recessive Centronuclear Myopathy

weakness. [research.pasteur.fr]

The autosomal recessive (AR) form presents from birth to childhood, followed by a mild progression of muscle weakness. [ncbi.nlm.nih.gov]

In the most severe cases newborns and infants may die, while milder mutations result only in mild weakness and some effects on activities of daily living (ADL). [emedicine.medscape.com]

Muscular Dystrophy-Dystroglycanopathy Type C3

There was proximal weakness in both upper and lower extremities. There was also mild weakness of ankle dorsiflexion and plantar flexion. [omicsonline.org]

[…] with severe cardiomyopathy to a much more benign adult onset with mild weakness and slow progression. [now.aapmr.org]

Mild to moderate elevated serum creatine kinase levels and positive Gowers sign are reported. [orpha.net]

Mitochondrial Myopathy with Cataract

Bilateral cataract needing surgical treatment at 32 was the prominent symptom in her daughter, then with only mild facial weakness. [pubmed.ncbi.nlm.nih.gov]

16p12.2 Microdeletion Syndrome

Common characteristics that have been described in people with a 16p12.2 microdeletion include developmental delay, delayed speech, intellectual disability that ranges from mild [encyclopedia.pub]

[…] to profound, weak muscle tone (hypotonia), slow growth resulting in short stature, an usually small head (microcephaly), malformations of the heart, recurrent seizures (epilepsy [encyclopedia.pub]

GALOP Syndrome

Neurologic examination disclosed mild to moderate distal weakness in the feet, right more than left, and mild weakness of the left interossei and triceps muscles. [go.gale.com]

She exhibited mild distal weakness and sensory loss in the legs, a positive Romberg, and an unsteady gait. Serum immunofixation disclosed a monoclonal IgM-kappa protein. [pubmed.ncbi.nlm.nih.gov]

She exhibited mild distal weakness and sensory loss in the legs, a positive Romberg, and an unsteady gait. [go.gale.com]

Myotonic Dystrophy Type 2

The clinical picture is dominated by the presence of myotonia and other minor muscular complaints as mild episodic weakness and muscle hypertrophy. [ncbi.nlm.nih.gov]

Potassium-Aggravated Myotonia

Mild weakness may persist afterward, and the later development of a progressive myopathy is common. [neupsykey.com]

Attacks last from hours to days, and range from mild weakness to profound paralysis. Mutations associated with HypoKPP are on the calcium and sodium channels. [statpathtech.com]

The attacks can last from hours to days, with variable severity from mild weakness to profound paralysis. [statpearls.com]

Juvenile Dermatomyositis

Patients with JDM have varying symptoms ranging from mild muscle weakness like difficulty getting out of a chair or difficulty turning over in bed to severe symptoms including [rheumatology.org]

[…] profound weakness or difficulty swallowing. [rheumatology.org]

Patients can also develop rash or skin changes ranging from mild redness to more severe ulcer formation. [rheumatology.org]

Proximal Myopathy with Focal Depletion of Mitochondria

[…] proximal weakness Lab: elevated creatine kinase large areas of about one-third of type ii muscle fibers devoid of mitochondria with remaining mitochondria unusually large [malacards.org]

[…] muscle weakness, severe myalgias during and after exercise, and susceptibility to rhabdomyolysis. [orpha.net]

Neurological examination showed bilateral symmetric ptosis, mild ophthalmoparesis, mild weakness of orbicularis oculi, orbicularis oris and cervical flexor muscles reduced [academic.oup.com]

Azithromycin Poisoning

Common cases of food poisoning will typically include a few of the following symptoms: abdominal cramps diarrhea nausea vomiting loss of appetite mild fever weakness headache [healthline.com]