Miosis: Causes & Reasons

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Possible Causes for Miosis

Horner's Syndrome

Postoperatively, left ptosis and miosis had improved slightly. [ncbi.nlm.nih.gov]

Horner's syndrome is characterized by a classic triad of ipsilateral pupillary miosis, partial eyelid ptosis, and facial anhydrosis. [ncbi.nlm.nih.gov]

From Wikidata Jump to navigation Jump to search Human disease characterized by miosis (a constricted pupil), partial ptosis (a weak, droopy eyelid), apparent anhydrosis (decreased [wikidata.org]

Intrapontine Hemorrhage

or autonomic instability Cerebellum - Ataxia, usually beginning in the trunk, ipsilateral facial weakness, ipsilateral sensory loss, gaze paresis, skew deviation, miosis [en.wikipedia.org]

[…] apo-plectiform onset with fast developing coma, and show disturbance of vegetative function (disturbance of respiration, cardiac dysrhythmias, hyperthermia, hypertension), miosis [ncbi.nlm.nih.gov]

Mild ptosis with concurrent miosis OD was also found. [e-tjo.org]

Organophosphate Poisoning

No miosis or wheeze None Discharged 10 ED Porter Portering, 30 min in room with patient Giddiness HR 60/min, BP 132/79. [academic.oup.com]

Blurry or darkened vision can be present with miosis. [emergencymedicalparamedic.com]

Atropine sulphate was administered intravenously in repeated doses to all children with bradycardia, diarrhea, salivation, and miosis. [journals.lww.com]

Opiate Overdose

Opiate overdose is characterized by respiratory depression, reduced consciousness, and miosis. [symptoma.com]

Constricted pupils (miosis) or poor arousability in a slow-breathing patient further suggest opioid toxicity. [pulmccm.org]

[…] by, last update April 2, 2019 CLINICAL FEATURES miosis CNS depression respiratory depression complications of hypoxia: seizures, dysrrhythmia, brain injury MANAGEMENT Resuscitation [lifeinthefastlane.com]

Tetraethyl Pyrophosphate Poisoning

[…] the muscarinic effects of organophosphates are SLUDGE ( salivation, lacrimation, urination, diarrhea, GI upset, emesis ) and DUMBELS ( diaphoresis and diarrhea; urination; miosis [slideshare.net]

[…] the muscarinic effects of organophosphates are SLUDGE (salivation, lacrimation, urination, diarrhea, GI upset, emesis) and DUMBELS (diaphoresis and diarrhea; urination; miosis [authorstream.com]

Gastrointestinal Nausea/vomiting Increased salivation Abdominal cramps Diarrhoea Faecal incontinence Genitourinary Urinary continence Eyes Blurred vision Increased lacrimation Miosis [doctorsachin.wordpress.com]

Cholinergic Crisis

Other symptoms include increased sweating, salivation, bronchial secretions along with miosis (constricted pupils). [en.wikipedia.org]

Other symptoms include increased sweating, salivation, bronchial secretions along with miosis. [wikidoc.org]

In reply to Instructor, NCSBN : In addition, The Myasthenia Crisis caused Pupils-mydriasis but The Cholinergic crisis caused Pupils-Miosis [learningext.com]

Anterior Uveitis

External examination Miosis Endothelial dusting Aqueous flare and cells 20. [slideshare.net]

Clinical features: Symptoms: pain due to ciliary spasm, red eye, photophobia, decreased vision and tearing Signs: Circumcorneal ciliary injection, irregular pupil or miosis [dro.hs.columbia.edu]

He had circumcorneal congestion and had grade +4 cells and grade +3 flare in anterior chamber with posterior synechia and miosis. [slideshare.net]

Brain Stem Infarction

It is typified by vertigo, ipsilateral hemiataxia, dysarthria, ptosis and miosis. [tchain.com]

[…] structure that extends in the lateral aspect of the pons down into the medulla) Sympathetic pathway : ipsilateral Horner’s syndrome, that is partial ptosis and a small pupil (miosis [lifeinthefastlane.com]

Neurological examinations showed left ptosis and miosis, hoarseness, dysphagia, right mild hemiparesis, left ataxia of his extremities, and truncal ataxia. [hindawi.com]

Uveitis

Spasm of the ocular sphincter muscle causes miosis. [symptoma.com]

Pupillary miosis is common. Slit-lamp examination This is the most important aspect of the examination. [emedicine.com]

Mydriatics: Mydriatics are given to counter the severe miosis. [symptoma.com]

Brain Stem Hemorrhage

The fulminating malignant course is characterised by rapid onset of coma, miosis, tetraplegia and respiratory disturbances. [link.springer.com]

Carbachol

Instillation for miosis prior to eye surgery should be gentle and parallel to the iris face and tangential to the pupil border; discard unused portion. [syrianclinic.com]

[…] of Miosis Instill no more than 0.5 mL into the anterior chamber of the affected eye(s) for the production of miosis during ocular surgery. [ndrugs.com]

Adults: 0.5 ml of 0.01% (intraocular form) instilled gently into the anterior chamber for production of satisfactory miosis. [glowm.com]

Exposure to Nerve Gas

Symptoms may include miosis, red conjunctiva, dimmed or blurry vision, pain, nausea and vomiting, rhinorrhea, increased salivation, tightness in chest, cough, and dyspnea. [centerforhealthsecurity.org]

Miosis is a very characteristic symptom of nerve agent intoxication. Victims will often report difficulty in seeing (blurred & dimmed vision). [besurvival.com]

These include, intense constriction of the pupils (miosis) and severe eye pain, constriction of the bronchioles producing labored breathing, nausea and vomiting, lacrimation [sites.duke.edu]

Iritis

[…] iritis. [6], [4] IOP may be increased due to inflammatory process or it may be decreased due to damage of the ciliary body’s ability to produce aqueous humor. [10], [4] Miosis [eyewiki.aao.org]

Pupillary miosis is common. Slit-lamp examination This is the most important aspect of the examination. [emedicine.medscape.com]

[…] what is called an iris bombé. [9] Intractable secondary glaucoma may also result following traumatic iritis. [9] Symptoms Photophobia (pain when light enters eye; pain with miosis [eyewiki.aao.org]

Brain Stem Herniation

[…] insipidus Tonsillar Cerebellar tonsil below the foramen magnum Coma Apnea Hypertension Upward Flattened quadrigeminal cistern "Spinning top" midbrain Hydrocephalus Coma Miosis [derangedphysiology.com]

[…] severe cases Compression of the posterior midbrain (apparently, that gives it a "spinning top" appearance) Hydrocephalus Clinical features of upward brainstem herniation Coma Miosis [derangedphysiology.com]

Aromatic L-Amino Acid Decarboxylase Deficiency

Resulting signs and symptoms can include droopy eyelids (ptosis), constriction of the pupils of the eyes (miosis), inappropriate or impaired sweating, nasal congestion, drooling [ghr.nlm.nih.gov]

Autonomic symptoms may include droopy eye lids (ptosis ), constriction of the pupils of the eyes (miosis), inappropriate or impaired sweating, nasal congestion, drooling, [rarediseases.info.nih.gov]

Autonomic symptoms have included ptosis, miosis, paroxysmal sweating, nasal congestion, temperature instability, hypotension, and gastroesophageal reflux. [jn.nutrition.org]

Organophosphate Insecticide Antagonists

The pupillary response (resolution of miosis) is not considered an end point of atropine therapy, as miosis may persist for weeks after significant exposure [ 11 ]. [intjem.springeropen.com]

Miosis 2. Muscle Twitching and Fasciculations These two are not seen with Flit (2% chlordane with kerosene). [jpma.org.pk]

Miosis is commonly observed, as are symptoms of central nervous system (CNS) toxicity, such as anxiety and restlessness. [clinicaladvisor.com]

Neuroblastoma

Tumors in the neck or upper chest may cause Horner syndrome (ptosis, miosis, anhidrosis). [msdmanuals.com]

[…] often incidental Tracheal deviation with resulting stridor Superior Vena cava syndrome Cervical involvement (5%) produces the following symptoms: Horner’s syndrome (ptosis, miosis [pedclerk.bsd.uchicago.edu]

Phencyclidine Intoxication

Other findings less frequent but still suspect are opisthotonos, hypertension, tachypnea or hyperpnea, miosis, hyperreflexia, hypertonia, and rigidity. [journals.sagepub.com]

Oculocerebrorenal Syndrome

Leukocoria, miosis, microphthalmos and a shallow anterior chamber has been noted in neonates. The cataractous lenses may be small and abnormally formed. [disorders.eyes.arizona.edu]

Heroin Dependence

Decreased gastrointestinal motility (can cause constipation) Cough suppression Suppression of corticotropin-releasing factor and adrenocorticotropin hormone Pinpoint pupils (miosis [emedicine.medscape.com]

Opioid intoxication [ edit ] Signs and symptoms of opioid intoxication include: [5] [22] Decreased perception of pain Euphoria Confusion Desire to sleep Nausea Constipation Miosis [en.wikipedia.org]

Pilocarpus

It may also lead to ocular miosis. What Are The Side Effects /Adverse Reactions of Jaborandi? [amazondiscovery.com]

Substance Abuse

Abstract Hospital-wide rumors and anecdotal reports had suggested that there was a potentially serious problem of alcohol and drug abuse among the psychiatric patients of this hospital. The authors describe a systematic, evaluative approach which gave direct and detailed information on the nature and extent of[…] [ncbi.nlm.nih.gov]

Iatrogenic Opiate Addiction

A respiratory rate of 12 or less, with or without miosis and evidence of opioid abuse, is highly sensitive in predicting opioid overdose in the pre-hospital setting. [clinicaladvisor.com]

Fentanyl

Fentanyl, fentanyl analogs and other novel synthetic opioids are all full agonists of varying potencies at the μ-opioid receptor, leading to typical clinical effects of miosis [ncbi.nlm.nih.gov]

[…] and pediatric patients with an overall frequency of < 1% and are listed in descending frequency within each System/Organ Class: Cardiac disorders: cyanosis Eye disorders: miosis [rxlist.com]

Kappa 1: Spinal analgesia and miosis. Kappa 2: Dysphoria and psychotomimesis. Kappa 3: Supraspinal analgesia. [acilbook.com]

Metabolic Encephalopathy

Metabolic encephalopathy is a transient or permanent impairment of brain function resulting from physiological insufficiency or aberrant metabolic processes accompanying certain systemic illness such as diabetes or liver disease. Timely recognition and treatment of the predisposing condition can reverse the potential[…] [symptoma.com]

Pontine Glioma

A 36-year-old male was admitted with a 10-year history of gradually progressive left ear hearing loss, diplopia and right hemiparesis. Magnetic resonance imaging showed a left lateral pontine enhancing tumour and an additional cerebellopontine angle epidermoid tumour in close proximity forming a collision tumour. On[…] [ncbi.nlm.nih.gov]

Central Pontine Myelinolysis

Central pontine myelinolysis is a rare neurologic disorder defined by symmetric demyelination in the central base of the pons. It usually manifests with neurologic signs such as impaired consciousness, ataxia, spastic quadriparesis, pseudobulbar signs, and the locked-in syndrome which is related to a disconnection[…] [ncbi.nlm.nih.gov]

Cluster Headache

The examination would reveal ptosis and miosis and other associated sign. [symptoma.com]

METHODS/RESULTS: Ophthalmic features such as conjunctival injection, lacrimation, ptosis and miosis occur in the vast majority of patients with cluster headache, whereas co-existent [ncbi.nlm.nih.gov]

[…] conjunctival injection and/or lacrimation ipsilateral nasal congestion and/or rhinorrhoea ipsilateral eyelid oedema ipsilateral forehead and facial sweating ipsilateral miosis [healthcentral.com]

Malignant Glioma

Anal Chim Acta. 2017 Jul 25;978:1-9. doi: 10.1016/j.aca.2017.05.009. Epub 2017 May 16. Author information 1 Department of Chemistry, Beijing Key Laboratory of Microanalytical Methods and Instrumentation, The Key Laboratory of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, China. 2[…] [ncbi.nlm.nih.gov]

Anisocoria

Horner’s syndrome causes unilateral miosis, and the affected abnormal pupil either does not dilate or has a delayed dilation in the dark. [mmcneuro.wordpress.com]

The most common etiology that leads to unilateral miosis include sympathetic denervation (Horner syndrome), pharmacological miosis and iridocyclitis. [dusunenadamdergisi.org]

Evaluation Distinct pathways control miosis and mydriasis. The parasympathetic pathway causes miosis by activating the iris sphincter. [statpearls.com]