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3,057 Possible Causes for mitochondria

  • Appendicitis

    Indeed mitochondria are widespread in high energy requiring organs like brain, heart and muscles.[] BACKGROUND: Mitochondria are the energy producing organelles practically in every human cell except erythrocytes.[] […] safest pharmacological anesthetic agents for patients with ETFDH deficiency is challenging given that most of the general anesthetic medications have multiple effects on mitochondria[]

  • Endocrine Dysfunction

    Abstract Mitochondria are critical organelles for endocrine health; steroid hormone biosynthesis occurs in these organelles and they provide energy in the form of ATP for[] Role of mitochondria in steroidogenesis .. Best Pract. Res. Clin. Endocrinol. Metab. 26 , 771–790 (2012). 115. Guran, T. et al .[] […] diseases have been found to result from 250 monogenic defects encoded across two genomes: the nuclear genome and the ancient circular mitochondrial genome located within mitochondria[]

  • Dementia

    Golomb, an associate professor of medicine at the University of California, San Diego, suggests that one at-risk group may be people with defects in their mitochondria, the[]

  • Aging

    KEYWORDS: Aging; Cell fate; Mitochondria; Stem cell [Indexed for MEDLINE] Free full text[] The mitochondrial theory of aging suggests that free radical damage to our cells’ power source (mitochondria) leads to a loss of cellular energy and function over time.[] The biologic clock: the mitochondria? J Am Geriatr Soc 1972;20:145-147. 5. Hayflick L. The limited in vitro lifetime of human diploid cell strains.[]

  • Portal Hypertension

    Considering that mitochondria produce many of these ROS, our aim was to assess the effects of the oral mitochondria-targeted antioxidant mitoquinone on hepatic oxidative stress[] CONCLUSION: We propose mitochondria-targeted antioxidants as a novel treatment approach against portal hypertension and cirrhosis. 2017 John Wiley & Sons A/S.[]

  • Alkylating Agent

    […] of mitochondria-targeted Cbl.[] Inhibition of mt-HK II by glucose-6-phosphate retards the mitochondria to react with 3-BrPA.[] The central role of mitochondria in HN2-induced cell detachment is reinforced, suggesting that mitochondria acts as a key executor of reduced cell adherence during anoikis[]

  • Cardiac Arrest

    Moreover, we found that elongation of mitochondria was observed at 4 h after cardiac arrest, whereas fragmented mitochondria were significantly increased, along with concomitant[] Abstract Mitochondria change their morphology dynamically by continual fusion and fission processes to fulfill their function.[]

  • UV Exposure

    Abstract High-frequency ultrasound images were used to measure the thickness of the dermis and epidermis of four human subjects. These measurements were performed before and after a single exposure to ultraviolet radiation (UV). Doses ranging from 0.5 to 3 minimal erythema doses (MED) were delivered to the[…][]

  • Vacor

    Experts discuss their study of mitochondria and what happens when it malfunctions.[] We report here that Vacor specifically inhibits the NADH:ubiquinone reductase activity of complex I in mammalian mitochondria.[] The activity of other respiratory enzymes of mitochondria is unaffected by Vacor at concentrations that completely inhibit the redox and energetic function of complex I.[]

  • Hepatitis B

    Muscle biopsy revealed myogenic lesion with abnormality of mitochondria and fat metabolism.[] The accumulation of lactic acid causes LA, while lack of energy leads to cell dysfunction and mitochondria-associated disease, including RM.[] As mitochondria are the main sites of oxidative phosphorylation, there will be an increase of pyruvate reduction to lactic acid and insufficient adenosine triphosphate.[]

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