Create issue ticket

3,057 Possible Causes for mitochondria

  • Appendicitis

    Indeed mitochondria are widespread in high energy requiring organs like brain, heart and muscles.[ncbi.nlm.nih.gov] BACKGROUND: Mitochondria are the energy producing organelles practically in every human cell except erythrocytes.[ncbi.nlm.nih.gov] […] safest pharmacological anesthetic agents for patients with ETFDH deficiency is challenging given that most of the general anesthetic medications have multiple effects on mitochondria[ncbi.nlm.nih.gov]

  • Endocrine Dysfunction

    Abstract Mitochondria are critical organelles for endocrine health; steroid hormone biosynthesis occurs in these organelles and they provide energy in the form of ATP for[ncbi.nlm.nih.gov] Role of mitochondria in steroidogenesis .. Best Pract. Res. Clin. Endocrinol. Metab. 26 , 771–790 (2012). 115. Guran, T. et al .[nature.com] […] diseases have been found to result from 250 monogenic defects encoded across two genomes: the nuclear genome and the ancient circular mitochondrial genome located within mitochondria[ncbi.nlm.nih.gov]

  • Dementia

    Golomb, an associate professor of medicine at the University of California, San Diego, suggests that one at-risk group may be people with defects in their mitochondria, the[scientificamerican.com]

  • Aging

    KEYWORDS: Aging; Cell fate; Mitochondria; Stem cell [Indexed for MEDLINE] Free full text[ncbi.nlm.nih.gov] The mitochondrial theory of aging suggests that free radical damage to our cells’ power source (mitochondria) leads to a loss of cellular energy and function over time.[nutritionfacts.org] The biologic clock: the mitochondria? J Am Geriatr Soc 1972;20:145-147. 5. Hayflick L. The limited in vitro lifetime of human diploid cell strains.[sens.org]

  • Portal Hypertension

    Considering that mitochondria produce many of these ROS, our aim was to assess the effects of the oral mitochondria-targeted antioxidant mitoquinone on hepatic oxidative stress[ncbi.nlm.nih.gov] CONCLUSION: We propose mitochondria-targeted antioxidants as a novel treatment approach against portal hypertension and cirrhosis. 2017 John Wiley & Sons A/S.[ncbi.nlm.nih.gov]

  • Alkylating Agent

    […] of mitochondria-targeted Cbl.[ncbi.nlm.nih.gov] Inhibition of mt-HK II by glucose-6-phosphate retards the mitochondria to react with 3-BrPA.[ncbi.nlm.nih.gov] The central role of mitochondria in HN2-induced cell detachment is reinforced, suggesting that mitochondria acts as a key executor of reduced cell adherence during anoikis[ncbi.nlm.nih.gov]

  • Cardiac Arrest

    Moreover, we found that elongation of mitochondria was observed at 4 h after cardiac arrest, whereas fragmented mitochondria were significantly increased, along with concomitant[ncbi.nlm.nih.gov] Abstract Mitochondria change their morphology dynamically by continual fusion and fission processes to fulfill their function.[ncbi.nlm.nih.gov]

  • UV Exposure

    Abstract High-frequency ultrasound images were used to measure the thickness of the dermis and epidermis of four human subjects. These measurements were performed before and after a single exposure to ultraviolet radiation (UV). Doses ranging from 0.5 to 3 minimal erythema doses (MED) were delivered to the[…][ncbi.nlm.nih.gov]

  • Vacor

    Experts discuss their study of mitochondria and what happens when it malfunctions.[books.google.de] We report here that Vacor specifically inhibits the NADH:ubiquinone reductase activity of complex I in mammalian mitochondria.[ncbi.nlm.nih.gov] The activity of other respiratory enzymes of mitochondria is unaffected by Vacor at concentrations that completely inhibit the redox and energetic function of complex I.[ncbi.nlm.nih.gov]

  • Hepatitis B

    Muscle biopsy revealed myogenic lesion with abnormality of mitochondria and fat metabolism.[ncbi.nlm.nih.gov] The accumulation of lactic acid causes LA, while lack of energy leads to cell dysfunction and mitochondria-associated disease, including RM.[ncbi.nlm.nih.gov] As mitochondria are the main sites of oxidative phosphorylation, there will be an increase of pyruvate reduction to lactic acid and insufficient adenosine triphosphate.[ncbi.nlm.nih.gov]

Further symptoms