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333 Possible Causes for Mitral Valve Thickened

  • Streptococcal Infection

    Chronic rheumatic heart disease mostly affects the mitral valve , which can become thickened with calcification of the leaflets, often causing fusion of the commissures and[] Further endocarditis can develop with aseptic vegetations along the valve closure lines, in particular the mitral valve.[]

  • Mucopolysaccharidosis 1H

    The mitral valve was most commonly affected ( n  19), followed by the tricuspid ( n  7) and aortic ( n  3) valves.[] Valve insufficiency was present in 21 patients (50.0%).[] Fifteen patients (35.7%) had thickened or dysplastic valves. Ten patients (23.8%) had ventricular hypertrophy.[]

  • Secondary Polycythemia

    Investigation for the etiology was notable for secondary polycythemia and non-specific mitral valve thickening on transthoracic echocardiography (TTE).[] Subsequent transesophageal echocardiography (TEE) showed a heterogenous,1.1 cm mass on the anterior mitral valve leaflet.[]

  • Hyperglobulinemic Purpura

    The alterations in the ABCC6 gene responsible for PXE may also lead to arteries becoming calcified, the aortic and mitral valves thickened, and cardiovascular symptoms, such[]

  • Phentermine

    Evidence of mitral and tricuspid valve thickening was noted at echocardiography.[] ., in reporting a case of aortic cusp tear in a 28 year-old woman with a bicuspid aortic valve, attributed the tear to previous phentermine therapy.[]

  • Nakamura-Osame Syndrome

    Fig. 4: Mitral valve: thickened, myxomatous, short chordae tendinae. Mechanical mitral valve placed in leaflet. The valve was beyond repair.[] The pathologic mitral valve is symptomatic in about 42%, with markedly thickened and cartilage-like leaflets and edges.[] Fig. 3A: Mitral valve leaflet: thickened, redundant. Moderate central regurgitation. Subvalvular apparatus: nodular, thickened, fused.[]

  • Neurological Disorder

    There were also verrucal endocardiosis of the mitral valve and slight thickening of the glomerular basement membranes.[]

  • Adrenal Infarction

    5 mg, HC 20 mg, FC 50 μg 11 2.1 Mitral valve thickening AC (target INR 3.0–3.5), ASA 12 0.9 Mild cardiac failure, AC (target INR 3.0–3.5) Pancreatic adenocarcinoma HC 25 mg[] valve thickening Arterial hypertension, Infectious endocarditis AC (target INR 3.0–3.5) HC 25 mg, FC 50 μg 7 28.1 Splinter hemorrhages, livedo reticularis 2 flares of SLE[]

  • Kearns Sayre Syndrome

    We also observed mitral valve prolapse (MVP) with mild mitral regurgitation in two patients, and mitral valve thickening in 2 patients.[] Echocardiography showed prolapse with thickening and degeneration of both mitral valve leaflets but without mitral regurgitation.[] In our series, 2 patients had MVP, 1 of them with mitral valve thickening, and 1 patient had thickening without MVP but with mild mitral regurgitation.[]

  • Marchesani-Weill Syndrome

    LV, left ventricle; LA, left atrium; RV, right ventricle; RA, right atrium; Arrows indicate thickened mitral valve apparatus.[] At operation we found thickened mitral valve leaflets and chordal apparatus and mitral valve repair was done as described earlier.[] Using the same techniques as described earlier a commissurotomy of the thickened mitral valve was done and splitting of the chordal apparatus.[]

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