Monocytosis: Causes & Reasons

Possible Causes for Monocytosis

The diagnosis of CMML requires absolute monocytosis (> 1000/μL) in addition to other criteria outlined by the World Health Organization (WHO) classification.(1) Monocytosis [ncbi.nlm.nih.gov]

In the absence of dysplasia, an acquired clonal genetic abnormality is required or causes for reactive monocytosis have to be excluded. [ncbi.nlm.nih.gov]

KEYWORDS: Chronic myelomonocytic leukemia; Monocytosis; WHO classification [ncbi.nlm.nih.gov]

Childhood Hodgkin Lymphoma

The complete cell blood count may show neutrophilia or eosinophilia, lymphopenia or monocytosis, anemia or thrombocytopenia. [symptoma.com]

Infectious Mononucleosis

Infectious mononucleosis [현재위치]: 홈>임상의학>감염병학>바이러스 질환>전염성단핵구증(infectious mononucleosis) 검사 Positive EBV titers(IgG or IgM) (100%) Relative and absolute lymphocytosis(70%) Atypical monocytosis [clinicclinic2.cafe24.com]

For excessive monocyte counts more generally, see monocytosis. [en.wikipedia.org]

(excessive numbers of circulating monocytes),[63] but today it usually is used in its narrower sense of infectious mononucleosis, which is caused by EBV and of which monocytosis [en.wikipedia.org]

Acute Monocytic Leukemia

Diagnosis Aides: High serum lysozyme (3x normal) A peripheral monocytosis of > 5x 10 /L in an otherwise M2 marrow and increased lysozyme A peripheral monocytosis of >5 x 10 [med-ed.virginia.edu]

Flow cytometric analysis of monocytes as a tool for distinguishing chronic myelomonocytic leukemia from reactive monocytosis. [nature.com]

Mori et al. [ 13 ] described a 70-year-old man with peri-vertebral tumors and peripheral monocytosis of >1.0 × 109/L. [diagnosticpathology.biomedcentral.com]

Polycythemia Vera

Monocytosis (absolute monocyte count, AMC ≥ 1 × 10 9 /L) might accompany a spectrum of myeloid neoplasms, other than chronic myelomonocytic leukemia (CMML). [ncbi.nlm.nih.gov]

Normal or ↓ Normal, ↑ or ↓, may be hypochromatic or polychromatic ↓, teardrop cells Normal or ↓ (iron deficient anemia) WBC ↑, left shifted, basophilia, eosinophilia, rarely monocytosis [surgpathcriteria.stanford.edu]

Haematologica 2017;102:1511 Differential diagnosis Chronic myelogenous leukemia (CML): leukocytosis (WBC ranges from 12k/L to 1,000k/L, median 100k/L), basophilia, thrombocytosis, monocytosis [pathologyoutlines.com]

Myeloproliferative Disease

The bone marrow overproduces the myeloid white blood cells, particularly one called a monocyte (monocytosis). [verywellhealth.com]

No monocytosis, eosinophilia, or basophilia is present, nor is there a philadelphia chromosome or bcr-abl fusion gene (genes, abl). [icd10data.com]

Acute Myeloid Leukemia

Diagnosis Aides: High serum lysozyme (3x normal) A peripheral monocytosis of > 5x 10 /L in an otherwise M2 marrow and increased lysozyme A peripheral monocytosis of >5 x 10 [med-ed.virginia.edu]

Symptoms include splenomegaly, monocytosis with granulocytosis, and thrombocytopenia. leukemia cu´tis leukemia with leukocytic invasion of the skin marked by pink, reddish [medical-dictionary.thefreedictionary.com]

African Trypanosomiasis

Other, nonspecific laboratory findings include anemia, monocytosis, and markedly elevated serum levels of polyclonal IgM. [merckmanuals.com]

Leukemia

No other obvious cause for Leukocytosis (e.g. infection, Corticosteroid s) Step 1: Consider secondary causes based on white cell count differential Monocyte predominance (monocytosis [fpnotebook.com]

22) is often associated with a clinical and hematologic picture very similar to that seen in BCR-ABL1 -positive CML with basophilia, 58, 60 whereas thrombocytopenia and monocytosis [doi.org]

Chronic myelomonocytic leukemia A diagnosis of CMML requires both the presence of persistent PB monocytosis ≥1 × 10 9 /L and monocytes accounting for ≥10% of the white blood [doi.org]

Toxoplasmosis

Lymphadenopathy and asthenia may persist for several weeks, mimicking infectious mononucleosis, especially since monocytosis can be observed on blood smears. [dx.doi.org]

Disseminated Tuberculosis

The patient’s cytopenias and monocytosis were an initial clue that was consistent with disseminated TB. [shmabstracts.com]

Acute Leukemia

Chronic myelomonocytic leukemia A diagnosis of CMML requires both the presence of persistent PB monocytosis ≥1 × 10 9 /L and monocytes accounting for ≥10% of the white blood [bloodjournal.org]

[…] preceding chronic myelomonocytic leukemia • Both neutrophilic and monocytic cells and their precursors are present, each constituting at least 20% of the marrow cells • Monocytosis [slideshare.net]

Sarcoidosis

Monocytosis, occurring in the majority of sarcoidosis cases in the bloodstream, and an increased number of natural killer cells are a manifestation of an increased cellular [ncbi.nlm.nih.gov]

[…] leukopenia may reflect bone marrow involvement, but the most common mechanism is a redistribution of blood T cells to sites of disease.[64] Other nonspecific findings include monocytosis [en.wikipedia.org]

Hairy Cell Leukemia

[…] neoplastic hematopoietic disorders, such as lymphoma, myelodysplastic syndromes, multiple myeloma, aplastic anemia, severe megaloblastic anemia, severe lymphocytosis, severe monocytosis [ncbi.nlm.nih.gov]

Sideroblastic Anemia

[…] populations normal and microcytic hypochromic; occasional coarse basophilic stippling and Pappenheimer bodies; no dysplastic changes, minimal neutropenia, no myeloblasts, no monocytosis [pathologyoutlines.com]

Listeriosis

Isolation of a monocytosis-producing agent. Aust. J. Exp. Biol. 27 (1949) 123–131. Google Scholar 11. Berche, P., Gaillard, J. [link.springer.com]

Diagnosis Listeria monocytogenes is implicated when monocytosis is observed in the peripheral blood as well as the cerebrospinal fluid. [ncbi.nlm.nih.gov]

Graves Disease

[…] high TSHR-Ab level after cessation of antithyroid drug. [ 47 ] Associated hematological abnormalities include increased RBC mass, leucopenia with relative lymphocytosis, monocytosis [intechopen.com]

Listerial Meningitis

However emergence of opportunistic infections such as mycobacteria, listeria monocytosis, nocardiosis, and invasive aspergilosis raised safety concerns. [esciencecentral.org]

Immune Thrombocytopenic Purpura

Various hematologic abnormalities such as anemia, leukocytosis, monocytosis, lymphopenia, leucopenia, thrombocytopenia, thrombocytosis, leukemoid reactions and pancytopenia [ann-clinmicrob.biomedcentral.com]

Viral Hepatitis

The most common hematological findings include leukocytosis in 70% of cases, with predominantly lymphocytosis and monocytosis, and mild thrombocytopenia in up to 50%. [doi.org]

Langerhans-Cell Histiocytosis

bone marrow packed Stage IV Spleen > 6 cm (palpable below costal margin) and fever >1 month with or without any or all of the above systems involved Stage V “Special” monocytosis [ro-journal.biomedcentral.com]

T-Cell Acute Lymphoblastic Leukemia

The peripheral blood showed a marked leukocytosis (WBC count, 117 × 109/L) with 39% lymphoblasts, monocytosis, and left-shifted neutrophilic leukocytosis. [academic.oup.com]

The descriptive diagnosis of T-ALL, Ph+, p190 BCR-ABL1 variant with monocytosis vs blast phase CML was agreed upon by the review panel to reflect uncertainty as to whether [academic.oup.com]

Herpes Zoster

Definition/Description Herpes Zoster, commonly called Shingles, is characterized by a painful rash with blisters.[1] It results from reactivation of the dormant varicella-zoster virus, also known as chickenpox, that reactivates within sensory ganglia.[2] The painful rash is associated with an involved nerve root and its[…] [physio-pedia.com]

Chronic Kidney Insufficiency

Chronic kidney insufficiency affects a significant number of individuals in the developed countries, particularly the United States. The progressive nature of the disease and a substantial reduction in the quality of life over the period of time are the primary reasons why an early diagnosis is crucial. Anemia,[…] [symptoma.com]

Non-Hodgkin Lymphoma

You are here Home Types of Cancer Lymphoma - Non-Hodgkin Lymphoma - Non-Hodgkin This is Cancer.Net’s Guide to Lymphoma - Non-Hodgkin. Use the menu below to choose the Introduction section to get started. Or, you can choose another section to learn more about a specific question you have. Each guide is[…] [cancer.net]

Adenocarcinoma of the Prostate

Virchows Arch. 2013 Apr;462(4):429-36. doi: 10.1007/s00428-013-1385-5. Epub 2013 Feb 27. Abstract Ductal adenocarcinoma (DAC) of the prostate is thought to have worse prognosis than prostatic acinar carcinoma (PAC). We aimed to evaluate the prognostic significance of histopathological patterns of DAC. A series of[…] [ncbi.nlm.nih.gov]

Griseofulvin

Hematologic: Leukopenia, neutropenia, granulocytopenia, punctate basophilia, monocytosis. [robholland.com]

Rheumatoid Arthritis

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease that primarily involves the joints. RA causes damage mediated by cytokines, chemokines, and metalloproteases. Characteristically, peripheral joints (eg, wrists, metacarpophalangeal joints) are symmetrically inflamed, leading to progressive destruction of[…] [merckmanuals.com]

Septicemia

Objective: In patients receiving inappropriate empirical antimicrobial agents, delaying of time to report positive hemoculture (TRH) may cause delay switching from inappropriate antimicrobial agents to appropriate antimicrobial agents, and thus may increase mortality. We hypothesized that the patients with septicemia[…] [ncbi.nlm.nih.gov]

Hepatocellular Carcinoma

Hepatocellular carcinoma: A cancer arising from the liver cells (hepatocytes). Liver damage, manifested by cirrhosis (scarring), is a primary risk factor for liver cancer. Cirrhosis may be caused by viral hepatitis, primarily hepatitis B and C, alcohol abuse, hemochromatosis, certain autoimmune diseases of the liver, and[…] [medicinenet.com]