Mononuclear Cell Infiltrates Causes & Reasons

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Mononuclear Cell Infiltrates Symptom Checker: Possible causes include Oophoritis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Oophoritis

Immunotyping of the ovarian mononuclear cell infiltrate revealed a mixture of B cells (including plasma cells) and T cells (both T4 and T8 ), as well as numerous macrophages [ncbi.nlm.nih.gov]

Immunohistochemical study of the ovarian mononuclear cell infiltrate revealed a mixture of B- and T-lymphocytes. The plasma cells were polyclonal. [ncbi.nlm.nih.gov]

HLA complex Selective mononuclear cell infiltration into the theca layer of developing follicles of the ovary Association with other autoimmune diseases such as Addison disease [pathologyoutlines.com]

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Autoimmune Gastritis

Murine autoimmune gastritis replicates human gastritis in being characterized by a chronic inflammatory mononuclear cell infiltrate in the gastric mucosa, destruction of parietal [ncbi.nlm.nih.gov]

Abstract Experimental autoimmune gastritis (EAG) characterised by mononuclear cell infiltrate, parietal and zymogenic cell destruction and circulating autoantibodies to gastric [ncbi.nlm.nih.gov]

(5/5), patchy oxyntic gland mononuclear cell infiltration (5/5), intestinal and/or pseudo-pyloric metaplasia in corpus mucosa (4/5), and enterochromaffin cell hyperplasia [ncbi.nlm.nih.gov]

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Lymphomatoid Granulomatosis

Morphologically, there is a nodular polymorphous mononuclear cell infiltrate with prominent vascular infiltration and often necrosis. [ncbi.nlm.nih.gov]

Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable [ncbi.nlm.nih.gov]

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Temporal Arteritis

cell infiltrates or a granulomatous process with multinucleated giant cells. [ncbi.nlm.nih.gov]

In temporal artery biopsy, the most important (and mandatory) histological criterion for the diagnosis of GCA is a mononuclear cell infiltrate predominating at the media-intima [orpha.net]

[…] sedimentation rate (Westergren) greater than or equal to 50 mm/hour, and biopsy sample including an artery, showing necrotizing arteritis, characterized by a predominance of mononuclear [ncbi.nlm.nih.gov]

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Acute Interstitial Nephritis

Diffuse mononuclear cell infiltration was confirmed by renal biopsy and a Gallium (Ga)-67 scintigraphy revealed diffuse uptake of the isotope in both kidneys. [ncbi.nlm.nih.gov]

Most (78%) of cases had mononuclear cell infiltrates, no significant eosinophilic infiltrates were found, and glomeruli were not involved. [ncbi.nlm.nih.gov]

Kidney biopsy specimens from both patients showed interstitial infiltration by mononuclear cells composed mainly of CD138( ) plasmacytes and diffuse effacement of podocyte [ncbi.nlm.nih.gov]

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Mikulicz Disease

The histological characteristics of Küttner's tumor are severe fibrosis, atrophic acinus, and mononuclear cell infiltration. [link.springer.com]

cell infiltration, the so-called MD [ 3 ]. [basicmedicalkey.com]

(a) Specimens of minor salivary glands in MD revealed abundant IgG4-bearing mononuclear cells infiltrating around acinar and ductal cells. [doi.org]

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Insect Bite

[…] of mononuclear cells and eosinophils. [ncbi.nlm.nih.gov]

The presence of superficial dermal atypical mononuclear cells with epidermotropism and Pautrier microabscesses is suggestive of mycosis fungoides. [doi.org]

Most of the lesions were characterized by superficial and mid dermal to deep perivascular and interstitial, and occasionally periadnexal, inflammatory-cell infiltrate consisting [ncbi.nlm.nih.gov]

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Non-Cranial Giant Cell Arteritis

cell infiltration or granulomatous inflammation, usually with multinucleated giant cells Suspect giant cell arteritis if the person is aged 50 years or older with at least [gpnotebook.co.uk]

Typical features of include giant cells at the intima–media junction, fragmentation of the internal elastic lamina and a diffuse mononuclear cell infiltrate ( Figure 3 ). [cmaj.ca]

Mononuclear cell infiltrates in the adventitia form granulomas containing activated T cells and macrophages. [merckmanuals.com]

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Chronic Berylliosis

CBD with granuloma and/or mononuclear cell infiltrates in lung tissue; ‘probable CBD’: BAL-lymphocytosis and BeLPTb 1.) 4 of 5 Be-sensitized develop CBD Newman, 2005 [ 11 [occmed.oxfordjournals.org]

CBD: BeLPTb and granuloma or mononuclear cell infiltrates in lung biopsy 1.) 8.8% (22 of 229 Be-sensitized) develop CBD Newman, 1996 [ 15 ] Denver, Colorado Cross-sectionalb [occmed.oxfordjournals.org]

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Vulvitis

It typically appears as atrophic, shiny, erythematous plaques characterized by a dense, subepithelial mononuclear cell infiltrate largely composed of plasma cells.1 Very few [ncbi.nlm.nih.gov]

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Pericholangitis

The histological changes of the colon that occurred in all 6 rabbits were mononuclear cell and histocyte infiltration with sporadic… CONTINUE READING [semanticscholar.org]

The histological changes of the colon that occurred in all 6 rabbits were mononuclear cell and histiocyte infiltration with sporadic eosinophils, transmural infiltration, [ncbi.nlm.nih.gov]

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Sjögren Syndrome

Abstract Sjögren's syndrome (SS) is an autoimmune disease with mononuclear cell infiltration and destruction of the lacrimal gland and salivary glands, which cause dryness [ncbi.nlm.nih.gov]

The involvement of these glands is characterized by focal, mononuclear cell infiltrates that surround the ducts and replace the secretory units. [ncbi.nlm.nih.gov]

cell infiltrates. [ncbi.nlm.nih.gov]

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Acute Alcohol Intoxication

• In more advanced cases there is marked subepithelial and subserosal FIBROSIS, accompanied by MONONUCLEAR CELL INFILTRATION. [slideshare.net]

infiltrate: lymphocytes, plasma cells, macrophages. 2. [slideshare.net]

[…] the gallbladder muscle layer and subserosal tissue Rokitansky-Aschoff sinuses Entrapped epithelial crypts Ppseudodiverticula Pockets in the wall of the gallbladder 44. 1.Mononuclear [slideshare.net]

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Interstitial Nephritis

Light microscopic examination of the renal biopsy specimens showed expansion of mononuclear cell infiltration in the renal interstitium, inflammatory cell infiltration of [ncbi.nlm.nih.gov]

M/S- • Interstitial nephritis with mononuclear cell infiltrate. • Less interstitial infiltrate and eosinophils as compared to others. • Occasional granulomas can be seen. [slideshare.net]

His labial glandbiopsy demonstrated severe mononuclear cell infiltration around the ducts. [naosite.lb.nagasaki-u.ac.jp]

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Adenovirus Infection

[…] debris with a mononuclear cell infiltrate and generally mild architectural distortion ( Histopathology 2015;66:467 ) Microscopic (histologic) images Images hosted on other [pathologyoutlines.com]

are more common than Cowdry type A inclusions, which are eosinophilic to amphophilic with nuclear halos Usually present are necrotic cells, apoptotic bodies and cellular [pathologyoutlines.com]

[…] description Surface epithelial cells, especially goblet cells, are infected Cowdry type B nuclear inclusions with enlarged, homogeneous, smudgy basophilic nuclei (smudge cells [pathologyoutlines.com]

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Granulomatous Myositis

All granulomas consisting of epithelioid, infiltrating mononuclear cells and multinucleated giant cells had markedly increased numbers of CD45Ro-positive cells. [ncbi.nlm.nih.gov]

( 18639165 ) Collins S....Byrne E. 1999 27 Granulomatous myositis: pathologic re-evaluation by immunohistochemical analysis of infiltrating mononuclear cells. ( 9073027 ) [malacards.org]

Myositis, muscle atrophy, microtubular inclusion, and mononuclear cell infiltrates are found at histology [ 2 ]. [ajronline.org]

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Pulmonary Lymphomatoid Granulomatosis

The definite diagnosis of PLG hinges on histopathology, with mixed mononuclear cell infiltrate containing several CD20-positive large B-cells in a background of CD3-positive [journals.lww.com]

Key histologic features necessary for the diagnosis include a mixed mononuclear cell infiltrate that shows vascular infiltration, appreciable numbers of T-cells, and variable [nature.com]

cell infiltrate containing large and small lymphoid cells, often along with plasma cells and histiocytes, which replaces the lung parenchyma and shows vascular infiltration [nature.com]

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Berylliosis

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Desquamative Interstitial Pneumonia

Desquamative interstitial pneumonia is chronic lung inflammation characterized by mononuclear cell infiltration of the airspaces; it occurs almost exclusively in current or [merckmanuals.com]

The walls display a mild mononuclear infiltrate, and there is type II metaplasia of the alveolar lining cells. [histopathology-india.net]

However, electron microscopy has shown that the cells are macrophages. The lung architecture remains intact, so that the alveoli are readily recognized. [histopathology-india.net]

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Constipation

Crypt hyperplasia, with a decreased villi/crypt ratio Blunted or atrophic villi Mononuclear cell infiltration into the lamina propria Epithelial changes, including structural [worldgastroenterology.org]

[…] histological findings [ 20 ] in patients with celiac disease who are taking a gluten-containing diet are: Increased density of intraepithelial lymphocytes ( 25/100 epithelial cells [worldgastroenterology.org]

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Hypersensitivity

and pernicious anemia.[8] The pathological picture is one of mononuclear cell infiltration and tissue destruction. [dermatology.cdlib.org]

The mononuclear cell infiltration in the dermis was studied and classified as follow: scattered ( /-), mild ( ), moderate ( ) and intense ( ). [doi.org]

cell infiltration into the submucosa. [web.archive.org]

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Syringocystadenoma Papilliferum

The stroma contained a dense mononuclear cell infiltrate, which comprised predominantly of plasma cells. The sebaceous glands appeared to be normal. [ncbi.nlm.nih.gov]

Some of these cells showed a decapitation secretion. The deep dermis showed few tubular glands with lumina. [ncbi.nlm.nih.gov]

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Tubulointerstitial Nephritis-Uveitis Syndrome

Fig. 1 Renal biopsy specimen showing widespread interstitial inflammation with a predominant mononuclear cell infiltrate (haematoxylin and eosin stain). [academic.oup.com]

His labial glandbiopsy demonstrated severe mononuclear cell infiltration around the ducts. [naosite.lb.nagasaki-u.ac.jp]

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Rheumatoid Arteritis

cell infiltrates or granulomatous inflammation with multinucleated giant cells) RheumTutor’s Note In clinical practice, temporal artery abnormalities include tenderness, [rheumtutor.com]

In temporal artery biopsy, the most important (and mandatory) histological criterion for the diagnosis of GCA is a mononuclear cell infiltrate predominating at the media-intima [orpha.net]

cell infiltration or granulomatous inflammation, usually with multinucleated giant cells Color duplex ultrasonography of the temporal artery is a promising new diagnostic [aafp.org]

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Hyperacute Graft Rejection

 Cellular – mononuclear cell infiltrate  Humoral – vasculitis ACUTE CELLULAR:  Seen within initial months after transplantation.  Mononuclear cells accumulates in glomerular [slideshare.net]

(a) Acute cellular reaction is marked by an interstitial intense mononuclear cell infiltrate. Both CD4 and CD8 lymphocytes are present. [immunologyinfo.weebly.com]

Acute rejection is characterised by mononuclear cell infiltration of the graft. [surgeryonline.wordpress.com]

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Gingivitis

The synovium may show significant changes, even before visible cartilage degeneration has occurred, with infiltration of mononuclear cells, thickening of the synovial lining [arthritis-research.biomedcentral.com]

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Giant Cell Aortic Arteritis

In temporal artery biopsy, the most important (and mandatory) histological criterion for the diagnosis of GCA is a mononuclear cell infiltrate predominating at the media-intima [orpha.net]

Mononuclear cell infiltrates in the adventitia form granulomas containing activated T cells and macrophages. [msdmanuals.com]

Abnormal artery biopsy: biopsy specimen with artery showing vasculitis characterised by a predominance of mononuclear cell infiltration or granulomatous inflammation, usually [patient.info]

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Renal Arteritis

Renal biopsy revealed noncaseating granulomatous infiltration of arterial and arteriolar walls, a patchy mononuclear cell interstitial infiltrate, and no significant glomerular [ncbi.nlm.nih.gov]

[…] but which are nondiagnostic (such as a moderate interstitial mononuclear cell infiltrate with very mild tubulitis) De novo Glomerulonephritis Glomerulonephritis in the allograft [tpis.upmc.com]

Abnormal artery biopsy with either mononuclear cell infiltrate or granulomatous inflammation (with giant cells) Etiology/Causes The overall etiology of GCA is unkown [3]. [physio-pedia.com]

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Hypertension

increased collagen, frayed and broken elastin molecules, infiltration of vascular smooth muscle cells, macrophages and mononuclear cells, and increased matrix metalloproteinases [doi.org]

29,30 as well as a hypertrophied vascular smooth muscle layer. 31 Histological examination of the intima of stiffened vessels reveals abnormal and disarrayed endothelial cells [doi.org]

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Stomatitis

Intense inflammatory cell infiltration, predominantly neutrophils present immediately below the ulcer, mononuclear lymphocytes are seen in adjacent areas. [ncbi.nlm.nih.gov]

Commonly observed histopathological changes in the pre-ulcerative stage include infiltration of the epithelium by mononuclear (lymphocytic) cells before an edema, followed [bmcoralhealth.biomedcentral.com]

The epithelium on the margins of the ulcer shows spongiosis and there are many mononuclear cells in the basal third. [en.wikipedia.org]

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