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182 Possible Causes for Most Patients Have Adult Onset of Symptoms, Mutation in the CALM2 Gene, Ventricular Bigeminy

  • Ventricular Arrhythmia

    […] rhythm, ventricular bigeminy, ventricular ectopic beats, and ventricular escape rhythm) episodes from Electrocardiogram (ECG) signal.[ncbi.nlm.nih.gov] LQT15LQT15 is caused by heterozygous mutations in the CALM2 (Calmodulin 2) gene (114182) on chromosome 2p21.[en.wikipedia.org] In this paper, we report the case of a male adolescent with PHP type 1a who presented with hypocalcemia-induced ventricular extrasystoles (bigeminy, trigeminy) and mild corrected[ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms
  • Glycogen Storage Disease due to Muscle Phosphorylase Kinase Deficiency

    The onset of symptoms can occur in childhood or adulthood; most patients have adult onset.[rarediseases.org] There are autosomal recessive forms of GSD IX (caused by mutations in PHKB, PHKG1, PHKG2, CALM1, CALM2, and CALM3 ), a X-linked liver form (caused by mutations in PHKA2 ),[bmcmedgenet.biomedcentral.com] Notably, some individuals with phosphorylase kinase deficiency in muscle do not have any obvious symptoms.[rarediseases.org]

    Missing: Ventricular Bigeminy
  • Catecholaminergic Polymorphic Ventricular Tachycardia

    […] big, ventricular bigeminy; Dobl vent, ventricular doublets; VEs, ventricular extrasystoles; y, years.[revespcardiol.org] RYR2, CASQ2, KCNJ2 , ANK2, CALM1, CALM2, TRDN, SCN5A* Other Panels that Include this Diagnosis Notes on Genes: Priority Genes: These genes include 70% of the mutations that[admerahealth.com] The ECG during exercise stress test revealed multifocal PVCs when the sinus rate exceeded 130 bpm, followed by ventricular bigeminy and ventricular couplets (Fig. 1 ).[link.springer.com]

    Missing: Most Patients Have Adult Onset of Symptoms
  • Cardiomyopathy

    Frequent ventricular ectopics and ventricular bigeminy (seen with severe DCM). Ventricular dysrhythmias ( VT / VF ).[lifeinthefastlane.com]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Catecholaminergic Polymorphic Ventricular Tachycardia Type 2

    Exercise stress test induced ventricular bigeminy or polymorphic ventricular tachycardia in affected individuals.[ncbi.nlm.nih.gov] […] that have been discovered and only represent a small percentage of CPVT cases are TRDN (encoding triadin) and CALM1 (encoding calmodulin). 5,6 Mutations in the CALM2 gene[doi.org] Exercise on treadmill induced premature ventricular contraction in bigeminy and bidirectional ventricular tachycardia was induced during isoproterenol infusion.[ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms
  • Coronary Atherosclerosis

    Coronary artery disease (CAD) exhibits the rules of the multifactorial hereditary. Notwithstanding, the role of genetic factors in the prevalence of CAD is estimated very high. SIRT1 plays an athero-protective role and alterations in its expression have some important consequence in the metabolism, cholesterol, and[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Atrial Arrhythmia

    Abstract Although a long postventricular atrial refractory period (PVARP) may prevent the occurrence of pacemaker mediated tachycardias and inadvertent tracking of atrial arrhythmias in dual chamber (DDD) pacing, the maximum upper rate will necessarily be compromised. We tested the feasibility of using minute[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Myocardial Infarction

    Key Points Question What is the role of aldosterone antagonist therapy in patients with ST-segment elevation myocardial infarction without heart failure or left ventricular ejection fraction greater than 40%? Findings In this systematic review and meta-analysis of 10 randomized clinical trials with 4147 unique[…][doi.org]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Acute Myocardial Infarction

    We herein report the case of a 25-year-old Japanese woman with left-main-trunk acute myocardial infarction (LMT-AMI). She had cardiogenic shock, so emergency percutaneous intervention was performed. Intravascular ultrasound of LMT-AMI showed that the three-layered structure of the intima, tunica media, and[…][ncbi.nlm.nih.gov]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene
  • Premature Ventricular Contraction

    Example 3) Ventricular Bigeminy ECG (Example 1) Ventricular Bigeminy ECG (Example 2) Ventricular Bigeminy ECG (Example 3) Ventricular Trigeminy ECG (Example 1) Ventricular[healio.com] Voltage maps were acquired at baseline and after 14 weeks of ventricular bigeminy.[ncbi.nlm.nih.gov] Ventricular bigeminy occurs when every other beat is a PVC. No treatment is necessary for PVCs. If symptomatic, beta-blockers or antiarrhythmic drugs can be effective.[healio.com]

    Missing: Most Patients Have Adult Onset of Symptoms Mutation in the CALM2 Gene