Motor Abnormalities: Causes & Reasons

Possible Causes for Motor Abnormalities

Abnormal MEPs were defined by delayed central motor conduction time or absent MEP. [e-acn.org]

CONCLUSIONS: Minor EMG abnormalities were not associated with phenotypic differences in a clinical upper motor neuron disease population. [ncbi.nlm.nih.gov]

Conclusions: Minor EMG abnormalities were not associated with phenotypic differences in a clinical upper motor neuron disease population. [jhu.pure.elsevier.com]

Nutcracker Esophagus

CONCLUSIONS: These data prove that the esophageal motor abnormalities in patients with nutcracker esophagus, including asynchrony of CM and LM contraction, are related to [ncbi.nlm.nih.gov]

[…] symptoms are common in patients with esophageal motor abnormalities. [enotes.tripod.com]

Motor abnormalities may not be present with every swallow, so dysphagia may seem to wax and wane. [emedicine.medscape.com]

Colpocephaly

Patients may present with motor abnormalities, cognitive deficits, visual abnormalities, and seizures. [radiopaedia.org]

The following list includes common symptoms of colpocephaly.[3][4][5] partial or complete agenesis of the corpus callosum intellectual disability motor abnormalities visual [en.wikipedia.org]

[…] skills (HP:0002194), delayed fine motor skills (HP:0010862); abnormal lacrimal duct (HP:0011481); ptosis (HP:0000520); no choanal stenosis (-HP:0000452); normal nasal bridge [databases.lovd.nl]

Neuronal Ceroid Lipofuscinosis Type 13

Introduction This book, combining and updating two previous editions, is a unique source of information on the diagnosis, treatment, and follow-up of patients with inherited metabolic diseases. The clinical and laboratory data characteristic of the ever-growing number of rare metabolic conditions can be bewildering for[…] [link.springer.com]

Motility-Related Diarrhea

Patients who complain of increased frequency, urgency and incontinence but pass normal stool volumes often have an abnormality in the motor activity of the anorectum. [pubmed.ncbi.nlm.nih.gov]

Many factors that induce diarrhoea are associated with 'abnormal' and highly propagative forms of motor activity that can clear material through the gut, allowing insufficient [pubmed.ncbi.nlm.nih.gov]

[…] stool volume can be regarded as the end result of a vicious spiral (Figure 12) that may start with a primary abnormality in either motor activity or epithelial transport. [pubmed.ncbi.nlm.nih.gov]

Bruce-Winship Syndrome

abnormality (eg, scleroderma, diabetic neuropathy, intestinal obstruction), an anatomic abnormality (eg, small bowel diverticula, stricture, ischemia, blind loops), or small [emedicine.medscape.com]

[…] circulation, as seen in small bowel resection or regional enteritis Bile salt deconjugation due to small bowel bacterial overgrowth Stasis of intestinal content caused by a motor [emedicine.medscape.com]

Neuroleptic Malignant Syndrome

Also, in neuroleptic malignant syndrome, unlike most infections, altered mental status and motor abnormalities tend to precede hyperthermia. [msdmanuals.com]

Motor abnormalities: Patients may have generalized, severe muscle rigidity (sometimes with simultaneous tremor, leading to cogwheel rigidity), or, less often, dystonias, chorea [msdmanuals.com]

abnormalities are not expected. [msdmanuals.com]

Klippel-Feil Syndrome Type 4 with Nemaline Myopathy and Facial Dysmorphism

Thoracolumbar scoliosis Abnormality of the nervous system Motor delay Ear malformation Low-set ears Growth abnormality Short stature IMPORTANT NOTE: NIH does not independently [ncbi.nlm.nih.gov]

[…] delay Ptosis Abnormal facial shape Muscle weakness Myopathy And another 19 symptoms. [mendelian.co]

Thoracolumbar scoliosis Abnormality of the nervous system Motor delay Ear malformation Low-set ears Growth abnormality Short stature Etiology J Orthop Surg Res 2022 Nov 16 [ncbi.nlm.nih.gov]

3-Methylglutaconic Aciduria Type 5

[…] delay Motor delay Abnormality of the respiratory system Recurrent bronchitis Constitutional symptom Exercise intolerance Fatigue Ear malformation Macrotia Growth abnormality [ncbi.nlm.nih.gov]

[…] of the integument Fair hair Abnormality of the musculoskeletal system Gowers sign Skeletal myopathy Abnormality of the nervous system Gait disturbance Global developmental [ncbi.nlm.nih.gov]

[…] system 3-Methylglutaconic aciduria Abnormality of the immune system Cyclical neutropenia Granulocytopenia Neutropenia Recurrent infections in infancy and early childhood Abnormality [ncbi.nlm.nih.gov]

Hereditary Essential Tremor Type 2

Multiple sclerosis (MS) was excluded because there were no other motor or sensory abnormalities, and paralysis agitans, because there was no festination or gait and balance [ncbi.nlm.nih.gov]

Alternating Hemiplegia of Childhood

The mechanism of this ocular motor abnormality is unknown but may be unique to this disorder. [ncbi.nlm.nih.gov]

Evidence from recent studies suggests the disorder is characterized by tonic fits, dystonic posturing, and ocular motor abnormalities. [ncbi.nlm.nih.gov]

Note: Such as tonic spells, dystonic posturing, choreoathetoid movements, nystagmus or other ocular motor abnormalities and/or autonomic disturbances. [ichd-3.org]

Childhood Schizophrenia

Abnormal motor behaviors Abnormal motor behaviors such as rocking and arm-flapping can be an early warning sign of schizophrenia or an autism disorder. [healthcentral.com]

developmental abnormalities (eg, pervasive developmental disorder, intellectual disability), and motor abnormalities Increased prevalence of premorbid social difficulties [merckmanuals.com]

[…] also help distinguish childhood-onset schizophrenia from the adolescent/young adult form (1): More severe symptoms A strong family history Increased prevalence of genetic abnormalities [merckmanuals.com]

Charcot-Marie-Tooth Disease Type 2B2

Abnormality of the musculoskeletal system Distal amyotrophy Distal muscle weakness Abnormality of the nervous system Areflexia Decreased motor nerve conduction velocity Distal [ncbi.nlm.nih.gov]

[…] of the musculoskeletal system Distal amyotrophy Distal muscle weakness Abnormality of the nervous system Areflexia Decreased motor nerve conduction velocity Distal sensory [ncbi.nlm.nih.gov]

Joint Hyperlaxity Syndrome AR 99.92 3 of 3 TRPV4 Brachyrachia, Familial Digital Arthropathy- Brachydactyly, Hereditary Motor And Sensory Neuropathy, Metatropic Dysplasia [igenomix.es]

Musician Dystonia

Abnormal associative plasticity of the human motor cortex in writer's cramp. Brain. 2003;126(12):2586-96. [ Links ] 40. Altenmüller E, Müller D. [scielo.org.co]

A unifying motor control framework for task-specific dystonia. Nat Rev Neurol. 2018;14(2):116-24. [ Links ] 26. Frucht SJ. [scielo.org.co]

Abnormal interhemispheric inhibition in musician's dystonia - Trait or state? Park Relat Disord. 2016;25:33-8. [ Links ] 25. [scielo.org.co]

Monosomy 4p

[…] disability, severe Morphological central nervous system abnormality Motor stereotypy Periventricular cysts Seizure Tethered cord Ventriculomegaly Ear malformation Abnormal [ncbi.nlm.nih.gov]

[…] of the nervous system Absent septum pellucidum Cavum septum pellucidum Corpus callosum, agenesis of EEG abnormality Global developmental delay Hydrocephalus Intellectual [ncbi.nlm.nih.gov]

[…] the hip Generalized hypotonia Hip dislocation Kyphosis Microcephaly Micrognathia Radioulnar synostosis Rib fusion Rib segmentation abnormalities Scoliosis Vertebral fusion Abnormality [ncbi.nlm.nih.gov]

Intraventricular Hemorrhage of the Premature Infant

Mild neurodevelopmental impairment (developmental quotient (DQ) < 80 or motor abnormality on examination). [cochranelibrary.com]

Mitochondrial DNA-Related Leigh Syndrome and NARP

Table 3 Abnormal motor findings Full size table Figure 3 Abnormal motor findings at onset in relation to age of onset. [ojrd.biomedcentral.com]

This phenotype consists of significant cognitive and motor impairment and results in wheelchair dependence and typically abnormal Leigh syndrome brain MRI. [scielo.br]

The most common clinical features were abnormal motor findings (99.2%), followed by abnormal ocular findings (60.8%) (Table 2). [ojrd.biomedcentral.com]

3-Methylglutaconic Aciduria Type 8

Hemiparkinsonism

Ocular motor abnormalities in neurodegenerative disorders. Antoniades CA, Kennard C. Antoniades CA, et al. Eye (Lond). 2015 Feb;29(2):200-7. doi: 10.1038/eye.2014.276. [pubmed.ncbi.nlm.nih.gov]

The findings suggest that interventions to correct walking abnormalities such as veering in PD should incorporate vision-based strategies rather than solely addressing motor [vc.bridgew.edu]

PD motor disorders are very complex and interconnected [6]. [hindawi.com]

Abnormal Gastrointestinal Motility

Bassotti G, Gaburri M, Clausi GG, Pelli MA, Morelli A: Can idiopathic megacolon cause functional motor abnormalities in the upper gastrointestinal tract? [link.springer.com]

All six had demonstrable neuropathic abnormalities by antroduodenal manometry, including the following: nonpropagated antral bursts, absent migrating motor complexes, postprandial [ncbi.nlm.nih.gov]

Esophageal and gastric motor abnormalities in gastroesophageal reflux during infancy. Gastroenterology 1983;84:741-746. 2. Di Lorenzo C, Piepsz A, Ham H, Cadranel S. [hon.ch]

Joubert Syndrome Type 4

Other characteristic features of the condition include episodes of unusually fast (hyperpnea) or slow (apnea) breathing in infancy, and abnormal eye movements (ocular motor [medlineplus.gov]

COL4A1-Related Disorders

abnormalities. [ncbi.nlm.nih.gov]

Neurologic examination showed a wide spectrum of motor abnormalities: pyramidal signs and spasticity were reported in 21 new patients, dystonic features in 7, and hypotonia [ncbi.nlm.nih.gov]

abnormalities on neurologic examination, with involvement of both pyramidal and extrapyramidal systems. [ncbi.nlm.nih.gov]

3-Methylglutaconic Aciduria Type 1

3-Methylglutaconic Aciduria Type 9

Jaberi-Elahi Syndrome

The patients did not have ataxia or dystonia, but had variable motor abnormalities, including hypotonia, spasticity, and choreoathetosis, and all had seizures. [findzebra.com]

[…] seizures Global developmental delay Globus pallidus hypointensity on susceptibility-weighted imaging Hypoplasia of the corpus callosum Inability to walk Intellectual disability Motor [ncbi.nlm.nih.gov]

And Speech Delay And Behavioral Abnormalities Optic atrophy, Hyperactivity, Aggressive behavior OMIM:619470 Intellectual Developmental Disorder, X-Linked 104 Optic atrophy [mousephenotype.org]

Charcot-Marie-Tooth Disease Type 2J

This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. [hon.ch]

Joint Hyperlaxity Syndrome AR 99.92 3 of 3 TRPV4 Brachyrachia, Familial Digital Arthropathy- Brachydactyly, Hereditary Motor And Sensory Neuropathy, Metatropic Dysplasia [igenomix.es]

HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. [hon.ch]

Amyotrophic Lateral Sclerosis Type 4

[…] with l oss of myelinating fibers in the corticospinal and corticobulbar pathways abnormal motor conduction, normal sensory conduction Genetics cause is mostly unknown small [orthobullets.com]

Showing of 12 | Medical Terms Other Names Learn More: HPO ID 80%-99% of people have these symptoms Abnormal pyramidal sign 0007256 Abnormal upper motor neuron morphology Abnormal [rarediseases.info.nih.gov]

Pathologic features lower motor neuron signs loss of motor neurons within the anterior horns of the spinal cord and motor cranial nerve nuclei upper motor neuron signs degeneration [orthobullets.com]

Congenital Hypomyelinating Neuropathy

ABSTRACT CONTEXT: Hereditary peripheral neuropathies (hereditary motor-sensory neuropathies or hereditary demyelinating neuropathies) are abnormalities of Schwann cells and [anestesiarianimazione.com]

INTRODUCTION Hereditary motor-sensory neuropathies are abnormalities of axons or Schwann cells and their myelin sheaths, with peripheral nerve dysfunction. [anestesiarianimazione.com]

Charcot-Marie-Tooth Disease Type 2R

This condition has been divided into two subtypes, hereditary motor and sensory neuropathy (HMSN) types I and II. [hon.ch]

Joint Hyperlaxity Syndrome AR 99.92 3 of 3 TRPV4 Brachyrachia, Familial Digital Arthropathy- Brachydactyly, Hereditary Motor And Sensory Neuropathy, Metatropic Dysplasia [igenomix.es]

HMSN I is associated with abnormal nerve conduction velocities and nerve hypertrophy, features not seen in HMSN II. [hon.ch]

Fucosidosis Type 1

Some symptoms they may experience include: intellectual disability delay in motor skills development impaired or slow growth (failure to thrive) abnormal skeletal development [childrenshospital.org]

The disease in the Springer Spaniel manifests as a mainly neurological syndrome with mixed motor and mental function deficits. [shop.labogen.com]

People with this condition often have delayed development of motor skills such as walking; the skills they do acquire deteriorate over time. [medlineplus.gov]