Motor Restlessness: Causes & Reasons

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Possible Causes for Motor Restlessness

Agitated Depression

Restlessness, nervousness, motor agitation, irritability, and excitement are combined with symptoms of depression. [alleydog.com]

This type of clinical depression can consist of feelings of irritation, restlessness, anger, insomnia, fidgeting, or racing thoughts. [livestrong.com]

[…] and akathisia present at the same time, which is very difficult to determine in everyday clinical practice. [ncbi.nlm.nih.gov]

Zotepine

(motor restlessness, especially in the legs, and resembling agitation) and dystonias such as muscle contractions causing unusual twisting of parts of the body, most often [library.neura.edu.au]

[…] than first generation antipsychotics, and may also cause less akathisia and dystonia. [library.neura.edu.au]

[…] such as repetitive, involuntary, and purposeless body or facial movements, Parkinsonism (cogwheel muscle rigidity, pill-rolling tremor and reduced or slowed movements), akathisia [library.neura.edu.au]

Attention Deficit Hyperactivity Disorder

The most obvious evidence of lowered vigilance is motor restlessness (fidgeting and moving about, yawning and stretching, talkativeness, or a combination of these) to improve [ncbi.nlm.nih.gov]

The most characteristic symptom of affected children was a marked motor restlessness (Kramer and Pollnow 1932, p. 1). [doi.org]

In contrast to the postencephalitic motor drive, the restlessness observed in the cases of Kramer and Pollnow could be observed only by day (Kramer and Pollnow 1932, p. 39 [doi.org]

Schizophrenia

Motor restlessness; not anxiety or agitation Five to 60 days Unknown Reduce dose or change drug; antiparkinsonian agents (benzodiazepines or propranolol [Inderal])† may help [aafp.org]

(dysphoric sense of motor restlessness) Parkinsonian symptoms of stiffness, resting tremor, difficulty with gait, and feeling slowed-down Orthostatic hypotension caused by [emedicine.medscape.com]

restlessness, fear of mental disintegration, poor adherence to treatment, and recent loss. 57 Overdose of treatment medications as a method of suicide is not common because [aafp.org]

Acute Amphetamine Intoxication

Integumentary Excessive sweating Rash, pruritus Abscess, cellulitis Gastrointestinal Abdominal pain Nausea/vomiting Constipation/diarrhea Jaundice Rectal pain Psychiatric Akathisia [clinicaladvisor.com]

Central Nervous System (CNS) - Stimulation of CNS, tremor, restlessness, agitation, insomnia, increased motor activity, headache, convulsions, coma and hyperreflexia are described [inchem.org]

[…] mouth”) Dental abscess Cardiovascular Tachycardia Hypertension Murmur Pulmonary Tachypnea Wheezing Central nervous system Hyperthermia Confusion Focal deficits Seizures Coma Akathisia [clinicaladvisor.com]

Dementia

restlessness. [doi.org]

[…] activity (such as restlessness, picking at clothes, or tapping fingers) or decreased motor activity (such as staring into space or moving very slowly); and disturbed sleep [health.harvard.edu]

Symptoms Dementia presents initially with restlessness, slight memory loss and depression. [symptoma.com]

Dysthymic Disorder

In terms of depressive symptom reduction there was a clear benefit for aripiprazole, but side effects in general, and specific such as general EPS, akathisia and weight gain [doi.org]

Extrapyramidal effects 2.4.3.1 EPS in general There was a significant difference in favour of the placebo group (n = 362, one RCT, OR 3.53; 95% CI 1.95 to 6.41). 2.4.3.2 Akathisia [doi.org]

Extrapyramidal effects Show forest plot 3 Odds Ratio (M‐H, Random, 95% CI) Subtotals only 8.1 EPS in general 1 362 Odds Ratio (M‐H, Random, 95% CI) 3.53 [1.95, 6.41] 8.2 akathisia [doi.org]

Bipolar Disorder

Extrapyramidal effects often manifest early and can include akathisia (i.e., subjective sense of motor restlessness); parkinsonism (i.e., cogwheel rigidity of tendons, masked [aafp.org]

Seventy-seven percent of patients discontinued lurasidone after median 103 days, because of adverse events in 54.1% (most often akathisia, sedation/somnolence, nausea, and [ncbi.nlm.nih.gov]

and ziprasidone increase the risk of extrapyramidal effects Aripiprazole is the only atypical antipsychotic not associated with dyslipidemia, but it is associated with akathisia [aafp.org]

Thioridazine

(motor restlessness, especially in the legs, and resembling agitation) and dystonias such as muscle contractions causing unusual twisting of parts of the body, most often [library.neura.edu.au]

Other signs of the condition include fidgety movements, leg swinging while sitting, rocking from foot to foot or pacing and motor restlessness. [worstpills.org]

trismus, torticollis, opisthotonos, oculogyric crises), tremor, muscular rigidity, akinesia, akathisia. [rxmed.com]

Aripiprazole

(condition of motor restlessness) No siginficant differences were found in incidence of discontinuation due to adverse events experienced by the aripiprazole group compared [centerwatch.com]

By 12 weeks, investigators reported no difference between aripiprazole and lithium (SAS, BAS, AIMS), except in terms of participant-reported akathisia (RR 2.97, 95% CI 1.37 [ncbi.nlm.nih.gov]

Aripiprazole can cause side effects including headache, insomnia, agitation, nervousness, lightheadedness, dizziness, somnolence, akathisia, and weight gain. [ncbi.nlm.nih.gov]

Risperidone

(motor restlessness, especially in the legs, and resembling agitation) and dystonias such as muscle contractions causing unusual twisting of parts of the body, most often [library.neura.edu.au]

These disorders include akathisia (motor restlessness), dystonia (abnormal muscle tone), and tardive dyskinesia (involuntary and repetitive movements). [ncbi.nlm.nih.gov]

This may include withdrawal symptoms or extrapyramidal symptoms such as muscle contractions, motor restlessness, rigidity, slowness of movement, tremor and irregular jerky [tabletwise.com]

Haldol

These include dystonia (continuous, often painful muscle spasms and contractions) and akathisia (motor restlessness). [epmonthly.com]

Other adverse neuromuscular reactions have been reported less frequently, but are often more severe, and include feelings of motor restlessness (i.e., akathisia), tardive [endoflifecare.tripod.com]

Adverse Effects List & Discussion Incidence more frequent Incidence less frequent AKATHISIA EXTRAPYRAMIDAL EFFECTS PARKINSON SYNDROME BREAST TENDERNESS GALACTORRHEA GYNECOMASTIA [endoflifecare.tripod.com]

Mania

AEs reported in ≥5% of cariprazine patients overall with at least twice the incidence of placebo were akathisia, extrapyramidal symptoms, restlessness, and vomiting. [ncbi.nlm.nih.gov]

Antipsychotic Agent

The patient factors include mild severity of akathisia, lack of apparent motor restlessness, no voluntary expression of inner restlessness, no clear communication of inner [doi.org]

Extrapyramidal effects: Dystonias (sustained contraction of muscles leading to twisting, distorted postures), Parkinson-like symptoms, akathisia (motor restlessness), and [brilliantnurse.com]

Akathisia (motor restlessness) is particularly unpleasant and may lead to nonadherence; it can be treated with propranolol. [merckmanuals.com]

Primary Torsion Dystonia

[…] dyskinesia in schizophrenic neuroleptic naive individuals, seven of which observed some spontaneous dyskinesia in these patients, including tremor, choreoathetosis, dystonia, and akathisia [omicsonline.org]

Thiothixene

Extrapyramidal symptoms are categorized as dystonic reaction, akathisia (subjective and objective motor restlessness), and pseudoparkinsonism. [iqb.es]

75% of the patients experienced akathisia by the seventh day. [ncbi.nlm.nih.gov]

Side effects on high dose included several instances of EPS: akathisia and tremor, and transient CNS stimulation. [ncbi.nlm.nih.gov]

Phenothiazine

Metoclopramide appears to result in roughly the same incidence of acute dystonic reactions, akathisia, or hypotension as the phenothiazines. [medical-dictionary.thefreedictionary.com]

These drugs have antipsychotic and, often, antiemetic properties, although they may also cause severe side effects such as extrapyramidal symptoms (including akathisia and [en.wikipedia.org]

Iron Deficiency Anemia

Abstract Ankaferd Blood Stopper (ABS) comprises a mixture of plants and stops bleeding via forming a protein network by erythroid aggregation. Bleeding causes reduction of iron levels in body. It has been indicated that ABS contains significant amount of iron. Thus, we investigated the biological activity of[…] [ncbi.nlm.nih.gov]

Chinese Restaurant Syndrome

I am in a restaurant in Glasgow where chopsticks stand ready in an eye-catching blue and yellow tin labelled Ve-Tsin Gourmet Powder. Produced by the Shanghai Guanshengyuan Tianchu Seasoning Company, the powder in question is monosodium glutamate (MSG). Apparently: “A sprinkling of Ve-Tsin will bring out the full[…] [theguardian.com]

Restless Legs Syndrome

KEYWORDS: Leg motor restlessness; Parkinson's disease; Restless legs syndrome [ncbi.nlm.nih.gov]

restlessness; (c) worsening of symptoms at rest with at least temporary relief by activity, and (d) worsening of symptoms in the evening or night. [ncbi.nlm.nih.gov]

Restless legs syndrome (RLS) is characterized by the desire to move the limbs associated with paresthesias of the legs, a motor restlessness, an intensification of symptoms [ncbi.nlm.nih.gov]

Rheumatic Fever

Rheumatic fever is a systemic inflammatory disease that may develop as a delayed reaction to an infection with group A beta-hemolytic streptococci. It is most often seen in children and young adults. Rheumatic fever does not present with specific signs and symptoms. There is sudden onset of fever, joint pain,[…] [symptoma.com]

Extrapyramidal Disorder

These symptoms include: Akathisia. Akathisia is a condition of motor restlessness. [healthfoxx.com]

These symptoms include dystonia (continuous spasms and muscle contractions), akathisia (motor restlessness), parkinsonism (characteristic symptoms such as rigidity), bradykinesia [en.wikipedia.org]

Akathisia reactions occur as a subjective experience of motor restlessness. [pocketdentistry.com]

Organophosphate Poisoning

To report a case of organophosphate poisoning treated with a continuous infusion of pralidoxime chloride. A 27-year-old white man presented with extreme agitation, muscle weakness and fasciculations, and respiratory failure after ingesting an organophosphate pesticide (Dursban, active ingredients chlorpyrifos and[…] [ncbi.nlm.nih.gov]

Tetanus

Tetanus is a preventable infectious disease caused by tetanus toxin (tetanospasmin) produced by Clostridium tetani. Tetanus is still an important health problem in low- and middle-income countries (LMICs). Botulinum toxin administration is a treatment approach that has been used in recent years to reduce rigidity[…] [ncbi.nlm.nih.gov]

Rabies

Rabies is a viral disease that causes inflammation of the brain in humans and other mammals. Early symptoms can include fever and tingling at the site of exposure. These symptoms are followed by one or more of the following symptoms: violent movements, uncontrolled excitement, fear of water, an inability to move[…] [en.wikipedia.org]

Drug-Induced Dystonia

(tardive dystonia) or motor restlessness (tardive akathisia) Medication-induced postural tremor Tremor that occurs when one tries to hold a body part still, against the force [hopkinsguides.com]

Akathisia reactions occur as a subjective experience of motor restlessness. [pocketdentistry.com]

AKATHISIA The word akathisia is a derivative of the Greek word meaning "not to sit." [uspharmacist.com]

Amantadine Toxicity

Buflomedil Poisoning

Frontal Lobe Epilepsy

Siddiqui M. M, Srivastava G, Saeed S. H. Diagnosis of Nocturnal Frontal Lobe Epilepsy (NFLE) Sleep Disorder Using Short Time Frequency Analysis of PSD Approach Applied on EEG Signal. Biomed Pharmacol J 2016;9(1) Manuscript received on :January 01, 2016 Manuscript accepted on :February 25, 2016 Published online on:[…] [biomedpharmajournal.org]

Amphetamine Poisoning