Motor-restlessness: Causes & Reasons

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Possible Causes for motor restlessness

Dysthymic Disorder

In terms of depressive symptom reduction there was a clear benefit for aripiprazole, but side effects in general, and specific such as general EPS, akathisia and weight gain [doi.org]

0.75; 95% CI 0.48 to 1.16). 9.4.2 Extrapyramidal effects 9.4.2.1 General EPS There was no significant difference (n 241, one RCT, OR 1.98; 95% CI 0.36 to 11.04). 9.4.2.2 Akathisia [doi.org]

Extrapyramidal effects Show forest plot 3 Odds Ratio (M‐H, Random, 95% CI) Subtotals only 8.1 EPS in general 1 362 Odds Ratio (M‐H, Random, 95% CI) 3.53 [1.95, 6.41] 8.2 akathisia [doi.org]

Acute Amphetamine Intoxication

Integumentary Excessive sweating Rash, pruritus Abscess, cellulitis Gastrointestinal Abdominal pain Nausea/vomiting Constipation/diarrhea Jaundice Rectal pain Psychiatric Akathisia [cancertherapyadvisor.com]

Central Nervous System (CNS) - Stimulation of CNS, tremor, restlessness, agitation, insomnia, increased motor activity, headache, convulsions, coma and hyperreflexia are described [inchem.org]

[…] mouth”) Dental abscess Cardiovascular Tachycardia Hypertension Murmur Pulmonary Tachypnea Wheezing Central nervous system Hyperthermia Confusion Focal deficits Seizures Coma Akathisia [cancertherapyadvisor.com]

Iron Deficiency Anemia

INTRODUCTION Iron deficiency anemia (IDA) is a common complication in routine clinical practice that frequently originates in the gastrointestinal (GI) tract[ 1 - 3 ]. Patients with IDA are therefore often referred to gastroenterologists for further examination and/or treatment. IDA associated with GI disorders can[…] [dx.doi.org]

Agitated Depression

[…] and akathisia present at the same time, which is very difficult to determine in everyday clinical practice. [ncbi.nlm.nih.gov]

The authors describe two cases of tardive akathisia following metoclopramide therapy, in which there were concomitant symptoms of agitated depression. [ncbi.nlm.nih.gov]

Restlessness, nervousness, motor agitation, irritability, and excitement are combined with symptoms of depression. [alleydog.com]

Dementia

restlessness. [doi.org]

[…] activity (such as restlessness, picking at clothes, or tapping fingers) or decreased motor activity (such as staring into space or moving very slowly); and disturbed sleep [health.harvard.edu]

Symptoms Dementia presents initially with restlessness, slight memory loss and depression. [symptoma.com]

Schizophrenia

Motor restlessness; not anxiety or agitation Five to 60 days Unknown Reduce dose or change drug; antiparkinsonian agents (benzodiazepines or propranolol [Inderal])† may help [aafp.org]

(dysphoric sense of motor restlessness) Parkinsonian symptoms of stiffness, resting tremor, difficulty with gait, and feeling slowed-down Orthostatic hypotension caused by [emedicine.medscape.com]

rigidity, bradykinesia, shuffling gait, tremor), and akathisia (e.g., inability to sit still, restlessness, tapping of feet). [aafp.org]

Bipolar Disorder

Extrapyramidal effects often manifest early and can include akathisia (i.e., subjective sense of motor restlessness); parkinsonism (i.e., cogwheel rigidity of tendons, masked [web.archive.org]

Seventy-seven percent of patients discontinued lurasidone after median 103 days, because of adverse events in 54.1% (most often akathisia, sedation/somnolence, nausea, and [ncbi.nlm.nih.gov]

and ziprasidone increase the risk of extrapyramidal effects Aripiprazole is the only atypical antipsychotic not associated with dyslipidemia, but it is associated with akathisia [web.archive.org]

Restless Legs Syndrome

KEYWORDS: Leg motor restlessness; Parkinson's disease; Restless legs syndrome [ncbi.nlm.nih.gov]

restlessness; (c) worsening of symptoms at rest with at least temporary relief by activity, and (d) worsening of symptoms in the evening or night. [ncbi.nlm.nih.gov]

Restless legs syndrome (RLS) is characterized by the desire to move the limbs associated with paresthesias of the legs, a motor restlessness, an intensification of symptoms [ncbi.nlm.nih.gov]

Mania

AEs reported in 5% of cariprazine patients overall with at least twice the incidence of placebo were akathisia, extrapyramidal symptoms, restlessness, and vomiting. [ncbi.nlm.nih.gov]

Attention Deficit Hyperactivity Disorder

The most obvious evidence of lowered vigilance is motor restlessness (fidgeting and moving about, yawning and stretching, talkativeness, or a combination of these) to improve [ncbi.nlm.nih.gov]

Defects in these regions could produce motor restlessness, particularly if the premotor areas normally inhibit other areas responsible for motor behavior in the adjacent motor [dx.doi.org]

Could these abnormal findings lead to the symptoms of attention deficit disorder with hyperactivity (motor restlessness, impulsiveness, and inattentiveness)? [dx.doi.org]

Chinese Restaurant Syndrome

Abstract The Chinese Restaurant Syndrome arose from an anecdote of discomfort experienced after eating Chinese cuisine. Monosodium glutamate has been implicated as the causative agent. Work over the past 17 years has consistently failed to reveal any objective sign accompanying the transient sensations that[…] [ncbi.nlm.nih.gov]

Primary Torsion Dystonia

[…] dyskinesia in schizophrenic neuroleptic naive individuals, seven of which observed some spontaneous dyskinesia in these patients, including tremor, choreoathetosis, dystonia, and akathisia [omicsonline.org]

Rheumatic Fever

Primary prevention of acute rheumatic fever is accomplished by proper identification and adequate antibiotic treatment of group A beta-hemolytic streptococcal (GAS) tonsillopharyngitis. Diagnosis of GAS pharyngitis is best accomplished by combining clinical judgment with diagnostic test results, the criterion standard[…] [ncbi.nlm.nih.gov]

Extrapyramidal Disorder

These symptoms include: Akathisia. Akathisia is a condition of motor restlessness. [healthfoxx.com]

These symptoms include dystonia (continuous spasms and muscle contractions), akathisia (motor restlessness), parkinsonism (characteristic symptoms such as rigidity), bradykinesia [en.wikipedia.org]

Akathisia reactions occur as a subjective experience of motor restlessness. [pocketdentistry.com]

Organophosphate Poisoning

To report a case of organophosphate poisoning treated with a continuous infusion of pralidoxime chloride. A 27-year-old white man presented with extreme agitation, muscle weakness and fasciculations, and respiratory failure after ingesting an organophosphate pesticide (Dursban, active ingredients chlorpyrifos and[…] [ncbi.nlm.nih.gov]

Tetanus

Tetanus, also known as lockjaw, is a serious but preventable disease that affects the body's muscles and nerves. It typically arises from a skin wound that becomes contaminated by a bacterium which is often found in soil. Symptoms usually begin eight days after the infection, and include headache and muscular[…] [wpro.who.int]

Drug-induced Dystonia

(tardive dystonia) or motor restlessness (tardive akathisia) Medication-induced postural tremor Tremor that occurs when one tries to hold a body part still, against the force [hopkinsguides.com]

Akathisia reactions occur as a subjective experience of motor restlessness. [pocketdentistry.com]

AKATHISIA The word akathisia is a derivative of the Greek word meaning "not to sit." [uspharmacist.com]

Rabies

Rabies is usually transmitted to humans through bites of infected animals; however, it can rarely be transmitted through deceased donor organs or tissues when not suspected. Here, we report a case of rabies transmission in a child. The child was a 5-year-old girl who was admitted to the pediatric intensive care[…] [ncbi.nlm.nih.gov]

Acute Gastroenteritis

Prochlorperazine induces akathisia in emergency patients. Ann Emerg Med. 1999;34(4 Pt 1):469–475. [PubMed] [Google Scholar] 121. Olsen JC, Keng JA, Clark JA. [ncbi.nlm.nih.gov]

Insect Bite

[…] activity can cause fasciculations, ataxia, restlessness and seizure-like movements. 13,14 Autonomic dysfunction can result in agitation, tachycardia, nausea and vomiting. [podiatrytoday.com]

These neuronal changes can result in excessive neuromuscular activity and autonomic dysfunction. 14 Systemic symptoms include cranial nerve abnormalities, excessive motor [podiatrytoday.com]

[…] dysfunction. 14 Cranial nerve abnormalities can cause abnormal eye movements, blurry vision, excessive salivation, tongue fasciculations and slurred speech. 13,14 Excessive motor [podiatrytoday.com]

Vitamin B12 Deficiency

Visual disturbances / decreased-blurred vision / damage of optic nerve Forgetfulness, memory loss Dementia / intellectual deterioration Impotence Paralysis Impaired fine motor [b12deficiency.info]

Abnormal reflexes Unsteady or abnormal gait / falls Ataxia (Neurological disorder affecting balance, coordination and speech) Balance problems Difficulty walking Dizziness Restless [b12deficiency.info]

Insomnia

Serious adverse events identified from case reports included fatal hepatotoxicity, restless legs syndrome, akathisia, and weight gain. [ncbi.nlm.nih.gov]

These include loud snoring and witnessed breathing pauses, which might suggest sleep apnea, and motor restlessness and involuntary leg movements, which might suggest restless [doi.org]

Iron Deficiency

[…] failure, pulmonary arterial hypertension, and restless legs syndrome (Ekbom syndrome), a neurologic disorder characterized by a distressing need or urge to move the legs (akathisia [cancertherapyadvisor.com]

Alcohol Abuse

There may be a dramatic loss of motor skills and coordination. Vision may be significantly blurred. [americanaddictioncenters.org]

Vision, hearing, and reaction time will likely be impaired. 0.13-0.15 percent: Now the person will likely experience less euphoria and possibly anxiety or restlessness. [americanaddictioncenters.org]

Pharyngitis

• Evaluate patient for onset of akathisia, tardive dyskinesia, and extrapyramidal effects. Watch for signs of increasing depression. [medical-dictionary.thefreedictionary.com]

Tell him tablet will disintegrate with or without liquid. • Tell patient drug may cause extra-pyramidal symptoms, akathisia, and tardive dyskinesia leading to involuntary [medical-dictionary.thefreedictionary.com]

Antidepressant Toxicity

Akathisia can be described as a subjective sense of unease and motor restlessness. It can be misinterpreted as increasing agitation or anxiety. [cancertherapyadvisor.com]

Tardive Dyskinesia/Dystonia, Parkinsonism & Akathisia S SRI & SSNRI antidepressants induced side-effects (Iatrogenic Extrapyramidal Symptoms) are recognized to be similar [antidepressantsfacts.com]

[…] secondary to urinary retention Neuro: Initially altered mental status including delirium and agitation followed by lethargy and stupor, seizure activity, myoclonus, dystonia, akathisia [coreem.net]

Bruxism

Akathisia reactions occur as a subjective experience of motor restlessness. [pocketdentistry.com]

The mesocortical disinhibition produced by SSRIs may lead to dopamine depletion that manifests itself as nocturnal bruxism, a specific form of akathisia. [ncbi.nlm.nih.gov]

PsicINFO databases from 1982 to 2001 was conducted, and the term bruxism and one of the following terms were used: drugs, medicine(s), pharmaceutical, movement disorders, akathisia [ncbi.nlm.nih.gov]

Pyramidal Tract Disorder

These symptoms include: Akathisia. Akathisia is a condition of motor restlessness. [healthfoxx.com]

G25.9 G25.69 Other tics of organic origin G25.7 Other and unspecified drug induced movement disorders G25.70 Drug induced movement disorder, unspecified G25.71 Drug induced akathisia [icd10data.com]

Extrapyramidal signs/symptoms are due to the side effects from dopamine blockade such as Dyskinesias (pseudoparkinsonism, dystonia, akathisia, tardive dyskinesia). [forums.studentdoctor.net]

Endogenous Depression

항진증 환자 경련성 질환 환자 또는 병력이 있는 환자 조울증 환자 뇌의 기실장해 또는 정신분열증의 소인이 있는 환자 배뇨곤란 또는 요저류의 병력을 가진 환자 녹내장 또는 안압 항진증 환자 소아 또는 고령자 과량독성(overdose)4) 장기간이나 고용량의 삼환계 항우울제 사용 후 갑작스런 중단은 정좌불능(akathisia [sdic.sookmyung.ac.kr]

Delirium

Here we present the case of an infant with multiple underlying medical risk factors who exhibited waxing and waning motor restlessness with disrupted sleep-wake cycles contributing [ncbi.nlm.nih.gov]

Potential side effects include extra-pyramidal symptoms (EPS), including parkinsonism, akathisia, and dystonia, and prolongation of the QTc interval, particularly with use [bcmj.org]

This may include inactivity or reduced motor activity, sluggishness, abnormal drowsiness, or seeming to be in a daze. Mixed delirium. [mayoclinic.org]