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54 Possible Causes for Mottled Pigmentation of Retina

  • Jalili Syndrome

    mottling, peripheral deep white dot deposits or retinal pigment epithelium (RPE) alterations in the inferonasal retina, decreased foveal and retinal thickness, attenuation[scitechnoljournals.wordpress.com] The macula appears atrophic with pigment mottling and the peripheral retina can resemble retinitis pigmentosa with bone spicule pigment changes.[disorders.eyes.arizona.edu] Affected individuals commonly suffer from photophobia, nystagmus, achromatopsia, night vision difficulties, optic disc pallor, narrow vessels, macular atrophy with pigment[scitechnoljournals.wordpress.com]

  • X-Linked Recessive Ocular Albinism

    Most of the times, the mottling of pigment in the retina of eyes is a significant indication of presence of X-linked ocular albinism.[ihealthblogger.com] Female obligate carriers are identified by finding patchy mottling or streaking of pigment in the midperipheral retina (pigmentary mosaicism), representing random X inactivation[orpha.net] In case, the mottling is not very prominent, the skin biopsy or hair bulb can be used to identify the disease as it shows unusual large granules of pigment in the individual[ihealthblogger.com]

  • Ocular Albinism

    pigmentation of the retina that can be detected in an eye examination.[steadyhealth.com] Most of the times, the mottling of pigment in the retina of eyes is a significant indication of presence of X-linked ocular albinism.[ihealthblogger.com] […] genetic defect since they have a functioning copy of the gene on the other X-chromosomes and therefore have little or no symptoms. 50-80% of female carriers, however, have mottled[steadyhealth.com]

  • Heimler Syndrome

    RESULTS: FA showed mottling of the retinal pigment epithelium (RPE) in the posterior pole and periphery of the retina.[ncbi.nlm.nih.gov] FAF revealed hyper and hypoautofluorescent dots corresponding to the RPE mottling observed on FA.[ncbi.nlm.nih.gov]

  • Hereditary Nystagmus

    Affected males have evidence of abnormal development of the central retina (macula) and the pigment of the retina appears irregular or 'mottled'.[disorders.eyes.arizona.edu]

  • Butterfly-Shaped Pigment Dystrophy

    The peripheral retina has diffuse pigment mottling. Drusen-like structures may be seen at the peripheral borders of the macular pigmentation.[disorders.eyes.arizona.edu] The deposition of pigment appears in the retinal pigment epithelium (RPE) level in a pattern more or less resembling the wings of a butterfly.[disorders.eyes.arizona.edu]

  • Zika Virus Disease

    Bilateral findings were found in 7 of 10 patients presenting with ocular lesions, the most common of which were focal pigment mottling of the retina and chorioretinal atrophy[ncbi.nlm.nih.gov] Mostly they revealed focal pigment mottling of the retina and chorioretinal atrophy (11/17 eyes) and optic nerve abnormalities (8/17 eyes) [ 7 ].[doi.org]

  • Bloch Sulzberger Syndrome

    A nearly consistent and pathognomonic finding is a pigment retinopathy (mottled diffuse hypopigmentations).[ncbi.nlm.nih.gov] A further consistent finding are abnormalities of peripheral retinal vessels with areas of non-perfusion in the outer retina.[ncbi.nlm.nih.gov] The retinal pigment epitheliopathy and the abnormalities of retinal vessels are thought to be the underlying pathognomonic findings, with all other ocular signs being secondary[ncbi.nlm.nih.gov]

  • Progressive Cone Dystrophy

    The patient had a mottled retina but no pigments (1, 2), extinguished scotopic electroretinographic response by impaired rod function, constricted visual fields (3), and bad[atlasophthalmology.net]

  • Amelogenesis Imperfecta

    The macula appears atrophic with pigment mottling and the peripheral retina can resemble retinitis pigmentosa with bone spicule pigment changes.[disorders.eyes.arizona.edu]

Further symptoms