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34 Possible Causes for mouse, neuregulin 3, protein

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  • Insulin-Like Growth Factor I

    […] but abrogated IGF-I-induced receptor autophosphorylation and phosphorylation of downstream kinases protein kinase B/Akt and MAPK/Erk (mouse proteins are reported).[ncbi.nlm.nih.gov] The encoded protein is processed from a precursor, bound by a specific receptor, and secreted.[genecards.org] (heregulins) ( 1, 2, 3, 4, 5 (tomoregulin, TMEFF) ) FGF FGFR1 Agonists: Ersofermin FGF ( 1, 2 (bFGF), 3, 4, 5, 6, 8, 10 (KGF2), 20 ) Repifermin Trafermin Velafermin FGFR2[en.wikipedia.org]

  • Cystic Fibrosis

    The effect of the number of cystic fibrosis (CF) alleles on cholera toxin (CT)-induced intestinal secretion was examined in the CF mouse model.[ncbi.nlm.nih.gov] Pulver and David Valle , Fine Mapping on Chromosome 10q22-q23 Implicates Neuregulin 3 in Schizophrenia , The American Journal of Human Genetics , 84 , 1 , (21) , (2009) .[doi.org] Here we report that CFTR interacts with the recently discovered protein, EBP50 (ERM-binding phosphoprotein 50).[ncbi.nlm.nih.gov]

  • Paclitaxel

    Gln22 of mouse MD-2 is essential for species-specific lipopolysaccharidemimetic action of Taxol . J Immunol 2001 ; 166: 11 - 14 .[doi.org] -1/antagonists & inhibitors Neuregulin-1/genetics Neuregulin-1/metabolism* Paclitaxel/pharmacology* Paracrine Communication Phosphatidylinositol 3-Kinases/metabolism Proto-Oncogene[ncbi.nlm.nih.gov] Recent reports suggest that chemotherapy-induced neuropathy is associated with signal transduction molecules, including protein kinase C and mitogen-activated protein kinases[ncbi.nlm.nih.gov]

  • Trastuzumab

    Immunoglobulin G1, anti-(human p185neu receptor) (human-mouse monoclonal rhuMab HER2 .gamma.1-chain), disulfide with human-mouse monoclonal rhuMab HER2 light chain, dimer[wikidata.org] Abstract This study was conducted to determine the role of neuregulin 1 (NRG1)-dependent human epidermal growth factor receptor 3 (HER3) activation in trastuzumab primary[ncbi.nlm.nih.gov] Mechanistically, UCA1 knockdown upregulated miR-18a and promoted miR-18a repression of Yes-associated protein 1 (YAP1).[ncbi.nlm.nih.gov]

  • Down Syndrome

    […] of DS phenotypes, thereby providing some references for the selection of specific mouse models in DS research.[ncbi.nlm.nih.gov] Leigh Ann Samsa, Cade Ellis Ito, Daniel Ross Brown, Li Qian and Jiandong Liu , IgG-Containing Isoforms of Neuregulin-1 Are Dispensable for Cardiac Trabeculation in Zebrafish[doi.org] […] region reporter assays, and gain- and loss-of-function experiments that miR-155 and -802 can regulate the expression of the predicted mRNA target, the methyl-CpG-binding protein[dx.doi.org]

  • Phenformin

    In vivo studies conducted in an H460 human lung cancer mouse model demonstrated that the drug-loaded micelles had greater anti-tumor efficacy, and reduced the population of[ncbi.nlm.nih.gov] 1 (NRG1), TP53 apoptosis effector (PERP) and sel-1 suppressor of lin-12-like (C. elegans) (SEL1L)] The data shown in Figs. 2 and 3 suggest that in addition to the destabilization[spandidos-publications.com] Activation of the unfolded protein response (UPR) is associated with the disruption of endoplasmic reticulum (ER) homeostasis and has been implicated in the pathogenesis of[ncbi.nlm.nih.gov]

  • Clear Cell Sarcoma

    We showed that trabectedin decreased the cell proliferation of five clear cell sarcoma cell lines in a dose-dependent manner in vitro and reduced tumor growth of two mouse[ncbi.nlm.nih.gov] […] member 11 0.385193 REST RE1-silencing transcription factor 0.374438 MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.365932 CD9 CD9 molecule 0.36187 YWHAE tyrosine 3-[amp.pharm.mssm.edu] Proteins[ncbi.nlm.nih.gov]

  • Pitt-Hopkins-Like Syndrome

    Through their mouse model, Sweatt and his colleagues connected the observed effects of Tcf4 and HDACs on gene expression in the brain.[news.vanderbilt.edu] Common genetic variation in Neuregulin 3 (NRG3) influences risk for schizophrenia and impacts NRG3 expression in human brain .[nature.com] protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking.[string-db.org]

  • Hirschsprung's Disease

    For mouse embryos, PCDHΑ9 was expressed in the stomach but rarely seen in the intestine during E10.5-12.5, then obviously expressed in the intestinal mucosa at E13.5 and extensively[ncbi.nlm.nih.gov] Zhang D, Sliwkowski MX, Mark M, Frantz G, Akita R, Sun Y, Hillan K, Crowley C, Brush J, Godowski PJ (1997) Neuregulin-3 (NRG3): a novel neural tissue-enriched protein that[doi.org] The protein and mRNA levels determined by Western blot and real-time quantitative PCR were consistent with that of immunohistochemistry.[ncbi.nlm.nih.gov]

  • Acute Disseminated Encephalomyelitis

    Macklin and Bruce Trapp , A mouse model for testing remyelinating therapies , Experimental Neurology , 283 , (330) , (2016) .[doi.org] (heregulins) ( 1 , 2 , 3 , 4 , 5 (tomoregulin, TMEFF) ) FGF FGFR1 Agonists: Ersofermin FGF ( 1 , 2 (bFGF) , 3 , 4 , 5 , 6 , 8 , 10 (KGF2) , 20 ) Repifermin Trafermin Velafermin[en.wikipedia.org] These data implicate myelin basic protein as an encephalitogen in these autoimmune diseases of the human nervous system, but suggest that immune responses to cerebroside and[dx.doi.org]