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11 Possible Causes for MRI Shows Globus Pallidus Signal Abnormalities

  • Hemochromatosis

    Brain MRI showed a pronounced signal decrease in the caudate nucleus, medial globus pallidus, and red nucleus.[doi.org] A second report also noted abnormal basal ganglia signal intensities on MRI. 2 All these cases included neurological involvement outside the basal ganglia in contrast to ours[doi.org]

  • Biotin-Responsive Basal Ganglia Disease

    The globus pallidus and cerebellum were spared in all patients.[archive.rsna.org] In 12 cases, discrete abnormal signal changes were observed in the mesencephalon, cortical-subcortical regions and thalami.[archive.rsna.org] The brain MRI showed bilateral lesions in the caudate heads in all cases with complete or partial involvement of the putamen.[archive.rsna.org]

  • Hemiballismus

    […] in patients with HCHB in HHNK shows T1-weighted hyperintensities in striatum and globus pallidus, with restricted diffusion on diffusion-weighted imaging. [15] An abnormal[jpalliativecare.com] […] in patients with HCHB in HHNK shows T1-weighted hyperintensities in striatum and globus pallidus, with restricted diffusion on diffusion-weighted imaging.[ 15 ] An abnormal[ncbi.nlm.nih.gov] […] globus pallidus and cerebral cortex, and the proposed theories were involvement of cortical-basal ganglia pathways along with presence of small infarct in basal ganglia. [14] MRI[jpalliativecare.com]

  • Hallervorden-Spatz Syndrome

    Her MRI did not show the typical “eye of the tiger” sign or pronounced low signal in the globus pallidus without the additional inserted bright signal that has now been well[jnnp.bmj.com] Extensive laboratory testing found no abnormalities to suggest an alternative diagnosis.[jnnp.bmj.com]

  • Senile Chorea

    Her MRI did not show the typical “eye of the tiger” sign or pronounced low signal in the globus pallidus without the additional inserted bright signal that has now been well[jnnp.bmj.com] Extensive laboratory testing found no abnormalities to suggest an alternative diagnosis.[jnnp.bmj.com]

  • Bilirubin Encephalopathy

    Both children have dystonia, athetosis, upward gaze palsy, and sensorineural hearing loss, with MRIs showing characteristic abnormal signal in the globus pallidus.[ncbi.nlm.nih.gov] The MRI shows high T2 signal in the globus pallidus.[neuropathology-web.org] Less severe injury is associated with mild neurological abnormalities, including hearing loss, which may be the only abnormality.[neuropathology-web.org]

  • Spondylometaphyseal Dysplasia

    Brain MRI at 3 days showed a simplified gyral pattern, mild narrowing of the foramen magnum at C2, and mild bilateral symmetric amorphous high T1 signal in the globus pallidus[diabetes.medicclub.info] Skeletal survey was markedly abnormal, with flattened vertebral bodies, absence of coronal clefts, 11 thoracic vertebrae, 6 lumbar vertebrae, squaring of the inferior scapulae[diabetes.medicclub.info]

  • Al-Gazali-Dattani Syndrome

    MRI of both patients showed abnormal signals in the globus pallidus bilaterally, although o...[findzebra.com] shows globus pallidus signal abnormalities METABOLIC FEATURES: Lactic acidosis, may be mild LABORATORY ABNORMALITIES: Serum and CSF lactate may be increased; Decreased activity[findzebra.com] […] retardation, mild; Ataxia; Gross motor delay; Fine motor delay; Drooling; Poor speech; Dystonia, episodic; Jerky head movements; Hyperreflexia; Choreoathetoid movements; MRI[findzebra.com]

  • Alopecia - Hypogonadism - Extrapyramidal Syndrome

    Brain MRI shows hypointense signal in the globus pallidus, striatum, thalamus, and dentate nucleus on T2-weighted images.[bloodgenetics.com] Abnormal hypointensities in the liver are also common; iron content is greater in the liver than in the basal ganglia.[bloodgenetics.com]

  • Ghosal Syndrome

    […] in patients with HCHB in HHNK shows T1-weighted hyperintensities in striatum and globus pallidus, with restricted diffusion on diffusion-weighted imaging. [15] An abnormal[jpalliativecare.com] […] globus pallidus and cerebral cortex, and the proposed theories were involvement of cortical-basal ganglia pathways along with presence of small infarct in basal ganglia. [14] MRI[jpalliativecare.com] signal may extend into the globus pallidus and up to the medial part of the cerebral peduncle in the midbrain along the striatonigral pathway. [16] Magnetic resonance spectroscopy[jpalliativecare.com]

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