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79 Possible Causes for Multifocal Epileptiform Discharges

  • Kohlschütter-Tönz Syndrome

    Kohlschutter-Tonz syndrome (KTS) is a rare autosomal-recessive disorder of childhood onset, and it is characterized by global developmental delay, spasticity, epilepsy, and amelogenesis imperfecta. In 12 KTS-affected individuals from a Druze village in northern Israel, homozygosity mapping localized the gene linked to[…][]

  • Neonatal Seizures

    More multifocal epileptiform discharges in EEG, more abnormal neuroimaging findings, and higher incidence of future developmental delay were noted in the group with later[]

  • Cerebral Palsy

    Netflix’s new series “Special” is an unconventional comedy about a gay man with cerebral palsy. The show, which debuts Friday, has eight 20-minute episodes and is based on actor Ryan O'Connell’s memoir: “I’m Special: And Other Lies We Tell Ourselves.” O’Connell stars in the series and serves as its executive[…][]

  • Lennox-Gastaut Syndrome

    Lennox-Gastaut Syndrome NORD gratefully acknowledges James W. Wheless, MD, Professor and Chief of Pediatric Neurology, Le Bonheur Chair in Pediatric Neurology, University of Tennessee Health Science Center; Director, Le Bonheur Comprehensive Epilepsy Program & Neuroscience Institute, Le Bonheur Children's Hospital,[…][]

  • Panayiotopoulos Syndrome

    Multifocal epileptiform discharges on EEG were identified in 84% of the patients. Two or more antiepileptic drugs were required in only 13% of the patients.[]

  • Progressive Myoclonic Epilepsy Type 7

    Girard showed slowing background with frequent generalized and multifocal epileptiform discharges in PME. [5] De Siqueira [6] found that photosensitivity with frequent interictal[]

  • Epilepsy

    Electroencephalogram is consistently abnormal, showing findings such as background slowing, multifocal and generalized epileptiform discharges and polyspikes.[]

  • Cerebral Cortical Atrophy

    epileptiform discharges Prominent nasal bridge Camptodactyly Pulmonic stenosis Metabolic acidosis Aciduria Spontaneous abortion Oligohydramnios Aortic valve stenosis Cardiomegaly[] […] of cardiovascular system morphology Congestive heart failure Hypospadias Polyhydramnios Retrognathia Abnormal heart morphology Hypertrophic cardiomyopathy Short philtrum Multifocal[]

  • Movement Disorder

    EEG was normal at six months but showed multifocal epileptiform discharges at 18months.[]

  • Infantile Convulsions and Choreoathetosis

    epileptiform discharges or a burst suppression pattern.[] […] first week of life. 16,17 A de novo missense mutation in a voltage-gated potassium channel subunit, Kv7.2, leads to refractory seizures and a grossly abnormal EEG exhibiting multifocal[]

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