Multifocal Independent Spikes Causes & Reasons

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Multifocal Independent Spikes Symptom Checker: Possible causes include Epilepsy. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Epilepsy

Epilepsy was defined conceptually in 2005 as a disorder of the brain characterized by an enduring predisposition to generate epileptic seizures. This definition is usually practically applied as having two unprovoked seizures 24 h apart. The International League Against Epilepsy (ILAE) accepted recommendations of a[…] [ncbi.nlm.nih.gov]

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West Syndrome

Other patterns, such as multifocal independent spike discharges (MISD), are present in the remainder. [ncbi.nlm.nih.gov]

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Myoclonic-Astatic Epilepsy

In a clinical setting, the occurrence of periodic clusters and independent focal or multifocal accentuations of generalized spike-and-wave complexes in interictal EEG may [ncbi.nlm.nih.gov]

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Generalized Clonic or Tonic-Clonic Seizures

Topic Overview Generalized tonic-clonic (grand mal) seizures are the easiest seizures to recognize. They happen most often in people with generalized epilepsy of unknown cause. A generalized tonic-clonic seizure begins with a sudden loss of consciousness. During the first 15 to 30 seconds of the seizure, the entire[…] [stlukesonline.org]

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Benign Adult Familial Myoclonic Epilepsy

Neurogenetics. 2008 May;9(2):139-42. doi: 10.1007/s10048-008-0118-4. Epub 2008 Jan 30. Abstract Benign adult familial myoclonic epilepsy (BAFME or FAME) is an autosomal dominant condition, characterized by shivering-like tremors of cortical origin, myoclonus, and epilepsy. Linkage to chromosomes 2p11.1-q12.2 and[…] [ncbi.nlm.nih.gov]

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Juvenile Myoclonic Epilepsy

We describe a patient who presented at our epilepsy-monitoring unit with myoclonic jerks, and was diagnosed with juvenile myoclonic epilepsy (JME). Imaging of his brain revealed partial agenesis of the corpus callosum (ACC). We discuss the known genetic basis of both JME and ACC, as well as the role of the corpus[…] [ncbi.nlm.nih.gov]

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Idiopathic Generalized Epilepsy

OBJECTIVES: Idiopathic generalized epilepsy (IGE) arises from paroxysmal dysfunctions of the thalamo-cortical network. One of the hallmarks of IGE is the absence of visible abnormalities on routine magnetic resonance imaging (MRI). However, recent quantitative MRI studies showed cortical-subcortical structural[…] [ncbi.nlm.nih.gov]

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Organic Brain Syndrome

Rogers MP, et al. Psychosom Med. 1986 Jul-Aug. Abstract Systemic mastocytosis is a disease characterized by an excessive accumulation of mast cells, and associated with skin lesions, flushing, diarrhea, tachycardia, and psychiatric manifestations. In order to define more clearly the psychiatric manifestations, ten[…] [ncbi.nlm.nih.gov]

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Encephalopathy

Posterior reversible encephalopathy syndrome is an encephalopathy that can be clinically characterized by headache, altered mental status and/or seizures. Neuroimaging demonstrates usually reversible bilateral subcortical vasogenic occipital-parietal edema. Exact pathophysiology remains unclear but is commonly[…] [ncbi.nlm.nih.gov]

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Juvenile Absence Epilepsy

We describe a 68-year-old woman who had typical absence seizures since 14 years of age. The absences were refractory to treatment and persisted into adulthood, with no seizure-free periods until seizure control at 59 years of age. After six years of being seizure-free, she presented with an episode[…] [ncbi.nlm.nih.gov]

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Uremic Encephalopathy

BACKGROUND AND PURPOSE: Uremic encephalopathy is a metabolic disorder in patients with renal failure. The purpose of this study was to describe the MR imaging findings of uremic encephalopathy. MATERIALS AND METHODS: This study retrospectively reviewed MR imaging findings in 10 patients with clinically proved uremic[…] [ncbi.nlm.nih.gov]

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Insulin Overdose

We report a very rare case of acute pulmonary edema caused by hypoglycemia from insulin overdose during an attempted suicide. A 16-year-old woman with type 1 diabetes was brought to our hospital because of hypoglycemic coma. She exhibited severe hypoxia; upon intubation, bloody froth poured out of the tube.[…] [ncbi.nlm.nih.gov]

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Lennox-Gastaut Syndrome

The interictal EEG record was suggestive of multifocal spike-and-wave discharges in both hemispheres, particularly in the left frontocentral, right parieto-temporo-occipital [pediatricneurosciences.com]

We did not include patients with interictal electrographic activity characterized by multifocal spikes, focal delta activity different to delta with maximum in the frontal [omicsonline.org]

[…] region, and left parieto-occipital region, with intermittent independent generalized polyspike wave discharge and intermittent 3-Hz generalized spike-and-wave discharges [pediatricneurosciences.com]

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Toxic Encephalopathy

Neurotoxicity following paradichlorobenzene (PDCB) exposure is rare and can occur in patients with pica and mothball or toilet cake ingestion. We present a rare case of toxic encephalopathy due to PDCB mothball inhalation and ingestion and describe the rapidly progressive leukoencephalopathy seen on computed[…] [ncbi.nlm.nih.gov]

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Early Infantile Epileptic Encephalopathy Type 3

Epileptic encephalopathy with suppression-burst in electroencephalography (EEG) can evolve into a few types of epileptic syndromes. We present here an unusual case of early myoclonic encephalopathy that evolved into migrating partial seizures in infancy. A female neonate initially had erratic myoclonus movements,[…] [ncbi.nlm.nih.gov]

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Hypoxic-Ischemic Brain Injury

Brain Dev. 2015 Feb;37(2):265-9. doi: 10.1016/j.braindev.2014.04.002. Epub 2014 Apr 29. Author information 1 Department of Pediatrics, Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan. Electronic address: pisces-koya@yacht.ocn.ne.jp. 2 Department of Neuromuscular Research, National Institute of Neuroscience, National[…] [ncbi.nlm.nih.gov]

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Generalized Motor Seizure

(A) Slow spike-and-waves and (B) multifocal independent spike discharges in two patients with GMS and mixed tonic, tonic–clonic, and myoclonic seizures. (From Tatum WO. [neupsykey.com]

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Status Epilepticus

multifocal. [onlinelibrary.wiley.com]

Name of the pattern: Periodic discharges, rhythmic delta activity or spike‐and‐wave/sharp‐and‐wave plus subtypes. [onlinelibrary.wiley.com]

27, 30-32 we propose the following terminology to describe EEG patterns in SE: Location: generalized (including bilateral synchronous patterns), lateralized, bilateral independent [onlinelibrary.wiley.com]

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Progressive Myoclonic Epilepsy Type 3

Patient 7 had focal bifrontal-central spike and slow wave discharges (Fig. 4B), independent left then right frontal central spike and slow wave discharges, and multifocal [academic.oup.com]

Patient 4 had independent occipital, parietal, and temporal spike and wave complexes as well as focal vertex spikes during photic stimulation. [academic.oup.com]

[…] slow spike and wave complexes. [academic.oup.com]

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Progressive Myoclonic Epilepsy Type 7

Patient 7 had focal bifrontal-central spike and slow wave discharges (Fig. 4B), independent left then right frontal central spike and slow wave discharges, and multifocal [academic.oup.com]

Patient 4 had independent occipital, parietal, and temporal spike and wave complexes as well as focal vertex spikes during photic stimulation. [academic.oup.com]

[…] slow spike and wave complexes. [academic.oup.com]

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Panayiotopoulos Syndrome

CONCLUSIONS: In PS all cerebral locations are able to spontaneously and independently generate and propagate interictal spikes, indicating that PS is a multifocal epileptic [ncbi.nlm.nih.gov]

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Ornithine Transcarbamylase Deficiency

An electroencephalogram (EEG) revealed multifocal independent spike-and-sharp-wave discharges. [ncbi.nlm.nih.gov]

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Familial Progressive Myoclonic Epilepsy

Six siblings, including 4 cases of myoclonic epilepsy, their parents and 2 grandmothers were subjected to systematic investigation, and the patients were followed-up. The genetic studies revealed in the mother's family a patient with Lafora bodies demonstrated at autopsy. No chromosome abnormalities were found nor[…] [ncbi.nlm.nih.gov]

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Miller Dieker Syndrome

Electroencephalography indicated frequent multifocal independent spikes, sharp waves, and early features of evolving hypsarrhythmia. [ssajm.org]

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Profound Mental Retardation

Multifocal independent spikes and polyspikes were eventually noted after the onset of epilepsy. [jmg.bmj.com]

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Subacute Sclerosing Panencephalitis

These may be synchronous with or independent of myoclonic jerks. MRI can reveal multifocal white-matter lesions. [epilepsy.com]

In addition there were multiple independent spikes and sharp waves. MRI showed high signal in the periventricular white matter. [ncbi.nlm.nih.gov]

The EEG often shows widespread cortical dysfunction with a burst-suppression pattern of high-amplitude slow-wave or spike -and-slow-wave complexes occurring at a rate of every [epilepsy.com]

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Hemimegalencephaly

[…] unilateral or bilateral high-amplitude spikes and spike-wave complexes. [scielo.br]

Interictal bilateral discharges may be generalized or independent. In the first months of life, unilateral suppression burst pattern or hypsarrhythmia may be present. [scielo.br]

Electroencephalographic abnormalities usually involve the affected hemisphere, with an asymmetric amplitude of the normal, age-related rhythms; slow, rhythmic or fast activity and multifocal [scielo.br]

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Porencephaly

The epileptic paroxysms showed multifocal independent spikes, which were not always localized in the defect or cleft sites at the last examination. [ncbi.nlm.nih.gov]

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Microcephaly with Spastic Quadriplegia

Multifocal independent spikes and polyspikes were eventually noted after the onset of epilepsy. [jmg.bmj.com]

spike Multiple independent spike foci MRI Brain Microcephaly, smooth thin cerebral cortex, simplified gyral pattern, global brain atrophy, delayed myelination, hypoplastic [bmcneurol.biomedcentral.com]

[…] discharge • Disorganized background In hyperekplexia cases • Hypsarrhythmia • Suppression burst Abnormal background activity bilaterally, low amplitude and frequent interictal multifocal [bmcneurol.biomedcentral.com]

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Cerebellar Hypoplasia and Atrophy

Multifocal independent spikes and polyspikes were eventually noted after the onset of epilepsy. [jmg.bmj.com]

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