Multifocal Independent Spikes: Causes & Reasons

Possible Causes for Multifocal Independent Spikes

In a clinical setting, the occurrence of periodic clusters and independent focal or multifocal accentuations of generalized spike-and-wave complexes in interictal EEG may [ncbi.nlm.nih.gov]

West Syndrome

Other patterns, such as multifocal independent spike discharges (MISD), are present in the remainder. [ncbi.nlm.nih.gov]

Developmental and Epileptic Encephalopathy Type 3

polyspike-waves and independent focal or multifocal spikes) with randomly asynchronous attenuation. [neurologyindia.com]

SB pattern may never be observed in a subgroup of EME cases resulting from NKHG. [4] However, EEG in them shows multiple paroxysmal abnormalities (generalized irregular spike-waves [neurologyindia.com]

Lennox-Gastaut Syndrome

There were also multifocal independent spikes, especially in the bilateral occipital and posterior temporal regions where the left side was more predominant than the right [frontiersin.org]

The interictal EEG record was suggestive of multifocal spike-and-wave discharges in both hemispheres, particularly in the left frontocentral, right parieto-temporo-occipital [pediatricneurosciences.com]

We did not include patients with interictal electrographic activity characterized by multifocal spikes, focal delta activity different to delta with maximum in the frontal [omicsonline.org]

Epilepsy

Seizures, abnormal movements or behavior due to unusual electrical activity in the brain, are a symptom of epilepsy. But not all people who appear to have seizures have epilepsy, a group of related disorders characterized by a tendency for recurrent seizures. Non-epileptic seizures (called pseudoseizures) are not[…] [webmd.com]

Benign Adult Familial Myoclonic Epilepsy

[…] familial cortical myoclonic tremor with epilepsy 1 Gene Detail Symbol: Name: ID: FCMTE1 familial cortical myoclonic tremor with epilepsy 1 GFS:22723 Gene name: FCMTE1 Chromosome: 8q24 Previous Symbols: Previous Names: Aliases: BAFME1, FAME1 Name Aliases: benign adult familial myoclonic epilepsy 1, "familial adult myoclonic[…] [genefaces.com]

Juvenile Myoclonic Epilepsy

Resource Links » Similar in PUBMED » Search Pubmed for Murthy J M » Search in Google Scholar for Murthy J M »Related articles Adolescent Developing Countries Diagnosis Differential Diagnostic Errors Electroencephalography Female Hospitals University Human India Male Medical Records Myoclonic Epilepsy Juvenile[…] [neurologyindia.com]

Idiopathic Generalized Epilepsy

Neuroimage Clin. 2014 Oct 24;6:455-62. doi: 10.1016/j.nicl.2014.10.008. eCollection 2014. Author information 1 Comprehensive Epilepsy Center, Department of Neurology, New York University School of Medicine, New York, NY 10016, USA. Abstract Magnetic resonance imaging (MRI) techniques have been used to quantitatively assess[…] [ncbi.nlm.nih.gov]

Organic Brain Syndrome

A 57-year-old man with no personal or family history of manic-depressive disease developed symptoms of hypomania after a cerebrovascular accident and surgical trauma to the brain. The patient responded well to lithium carbonate treatment over a 2-year period. Although this therapy is contraindicated in cases of[…] [ncbi.nlm.nih.gov]

Encephalopathy

Posterior reversible encephalopathy syndrome is an encephalopathy that can be clinically characterized by headache, altered mental status and/or seizures. Neuroimaging demonstrates usually reversible bilateral subcortical vasogenic occipital-parietal edema. Exact pathophysiology remains unclear but is commonly[…] [ncbi.nlm.nih.gov]

Uremic Encephalopathy

BACKGROUND AND PURPOSE: Uremic encephalopathy is a metabolic disorder in patients with renal failure. The purpose of this study was to describe the MR imaging findings of uremic encephalopathy. MATERIALS AND METHODS: This study retrospectively reviewed MR imaging findings in 10 patients with clinically proved uremic[…] [ncbi.nlm.nih.gov]

Insulin Overdose

We report a very rare case of acute pulmonary edema caused by hypoglycemia from insulin overdose during an attempted suicide. A 16-year-old woman with type 1 diabetes was brought to our hospital because of hypoglycemic coma. She exhibited severe hypoxia; upon intubation, bloody froth poured out of the tube.[…] [ncbi.nlm.nih.gov]

Toxic Encephalopathy

"Thinner" is a widely used industrial mixture of organic solvents. Exposure to organic solvents is usually not considered to be a possible cause of epilepsy, despite descriptions of toxic effects on the central nervous system. There are only a few reports about a possible epileptogenic effect of organic solvents[…] [ncbi.nlm.nih.gov]

Hypoxic-Ischemic Brain Injury

Homepage Rare diseases Search Search for a rare disease Neonatal hypoxic and ischemic brain injury ORPHA:137577 Synonym(s): HIE Hypoxic and ischemic brain injury in the newborn Hypoxic-ischemic encephalopathy Perinatal asphyxia Perinatal hypoxia Prevalence: 1-9 / 100 000 Inheritance: Not applicable Age of onset:[…] [orpha.net]

Juvenile Absence Epilepsy

Collapse all Expand all Contexte Il s'agit d'une version mise à jour de la revue Cochrane publiée en 2017. Les crises d'absence (CA) sont de brèves crises d'épilepsie qui surviennent pendant l'enfance et l'adolescence. Selon les caractéristiques cliniques et les résultats de l'électroencéphalogramme (EEG), elles sont[…] [cochranelibrary.com]

Familial Progressive Myoclonic Epilepsy

Six siblings, including 4 cases of myoclonic epilepsy, their parents and 2 grandmothers were subjected to systematic investigation, and the patients were followed-up. The genetic studies revealed in the mother's family a patient with Lafora bodies demonstrated at autopsy. No chromosome abnormalities were found nor[…] [ncbi.nlm.nih.gov]

TBC1D24-Related Disorders

In the initial stages of the disease, interictal record revealed regional or multiregional epileptiform discharges with formation of multifocal independent spike foci (MISF [intechopen.com]

Miller-Dieker Syndrome

Electroencephalography indicated frequent multifocal independent spikes, sharp waves, and early features of evolving hypsarrhythmia. [ssajm.org]

Microcephaly with Spastic Quadriplegia

Multifocal independent spikes and polyspikes were eventually noted after the onset of epilepsy. [jmg.bmj.com]

spike Multiple independent spike foci MRI Brain Microcephaly, smooth thin cerebral cortex, simplified gyral pattern, global brain atrophy, delayed myelination, hypoplastic [bmcneurol.biomedcentral.com]

[…] discharge • Disorganized background In hyperekplexia cases • Hypsarrhythmia • Suppression burst Abnormal background activity bilaterally, low amplitude and frequent interictal multifocal [bmcneurol.biomedcentral.com]

Ornithine Transcarbamylase Deficiency

An electroencephalogram (EEG) revealed multifocal independent spike-and-sharp-wave discharges. [ncbi.nlm.nih.gov]

Porencephaly

The epileptic paroxysms showed multifocal independent spikes, which were not always localized in the defect or cleft sites at the last examination. [ncbi.nlm.nih.gov]

Combined Oxidative Phosphorylation Deficiency 15

independent spike foci over the bilateral frontal and bilateral posterior head regions. [e-cep.org]

Repeated electroencephalography studies demonstrated poorly organized sleep feature, and nearly continuous asynchronous diffuse slow waves mixed with very frequent multifocal [e-cep.org]

Cerebellar Hypoplasia and Atrophy

Multifocal independent spikes and polyspikes were eventually noted after the onset of epilepsy. [jmg.bmj.com]

Pontocerebellar Hypoplasia Type 1B

Multifocal independent spikes and polyspikes were eventually noted after the onset of epilepsy. [jmg.bmj.com]

Epilepsy with Generalized Tonic-Clonic Seizures

(A) Slow spike-and-waves and (B) multifocal independent spike discharges in two patients with GMS and mixed tonic, tonic–clonic, and myoclonic seizures. (From Tatum WO. [neupsykey.com]

Infantile Symmetrical Thalamic Degeneration

Interictal EEGs show high-voltage slow waves and bilateral independent multifocal spike waves. [neupsykey.com]

Interictal EEGs in ZWS show bilateral independent multifocal spike waves, predominantly in the frontal motor cortex ( 59 ). [neupsykey.com]

Profound Intellectual Disability

Multifocal independent spikes and polyspikes were eventually noted after the onset of epilepsy. [jmg.bmj.com]

Lethal Neonatal Spasticity - Epileptic Encephalopathy

Interictal EEGs of the patients with Zellweger syndrome showed infrequent bilateral independent multifocal spikes, predominantly in the frontal motor cortex and its surrounding [thoracickey.com]

On day 3, the interictal EEG showed multifocal spikes. [ng.neurology.org]

During continuous video-EEG monitoring on day 8, multiple independent left and right frontal seizures were recorded. [ng.neurology.org]

Craniosytosis Mental Retardation Syndrome of Lin and Gettig

independent spike and waves Mild ventricular dilation, myelination delay Died after a refractory status epilepticus (age at death is not described). 7 Krepischi et al[ 14 [thieme-connect.com]

] 8 wk Atonic seizures, hypomotor seizures with apnea, clonic seizures followed by versive movement and apnea, and spasm-like seizures followed by apnea Dravet syndrome Multifocal [thieme-connect.com]

Progressive Myoclonic Epilepsy Type 3

Patient 7 had focal bifrontal-central spike and slow wave discharges (Fig. 4B), independent left then right frontal central spike and slow wave discharges, and multifocal [academic.oup.com]

Patient 4 had independent occipital, parietal, and temporal spike and wave complexes as well as focal vertex spikes during photic stimulation. [academic.oup.com]

[…] slow spike and wave complexes. [academic.oup.com]