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253 Possible Causes for Multifocal Independent Spikes, Slow-Frequency High-Amplitude Waves with High-Frequency Polyspikes, Variable Psychomotor Retardation

  • West Syndrome

    […] clinical manifestations such as hypotonia, psychomotor retardation, and feeding difficulties.[ncbi.nlm.nih.gov] Other patterns, such as multifocal independent spike discharges (MISD), are present in the remainder.[ncbi.nlm.nih.gov] Leigh syndrome (LS) (sub-acute necrotizing encephalomyelopathy) is characterized by symmetric brain lesions occurring mainly in the basal ganglia and associated with variable[ncbi.nlm.nih.gov]

  • Myoclonic-Astatic Epilepsy

    retardation mainly affecting speech.[ipfs.io] In a clinical setting, the occurrence of periodic clusters and independent focal or multifocal accentuations of generalized spike-and-wave complexes in interictal EEG may[ncbi.nlm.nih.gov] Boys (74%) are more often affected than girls (Doose and Baier 1987a). [2] Prognosis Epilepsy with myoclonic-astatic seizures has a variable course and outcome.[ipfs.io]

  • Epilepsy

    Contemporary drug therapy fails to control epileptic seizures in some 30% of patients, resulting in the need to employ other measures when they appear practicable. A good deal of potentially relevant statistical detail is available regarding the outcomes of the available antiepileptic therapies, but its interpretation[…][dx.doi.org]

    Missing: Variable Psychomotor Retardation
  • Generalized Clonic or Tonic-Clonic Seizures

    ‘Contrary to popular folk belief, nothing should be placed in the mouth during the seizure. Severe injury could occur.’ Generalized tonic clonic seizures (grand mal seizures) are the most common and best known type of generalized seizure. They begin with stiffening of the limbs (the tonic phase), followed by jerking[…][epilepsynw.org]

    Missing: Variable Psychomotor Retardation
  • Benign Adult Familial Myoclonic Epilepsy

    Abstract Benign adult familial myoclonic epilepsy (BAFME) has been mapped to chromosome 8q23.3-q24.1, 2p11.1-q12.1, 5p15.31-p15.1, and 3q26.32-3q28, in Japanese, Italian, Thai, and French pedigrees, respectively. Recently, we investigated a Chinese BAFME family. Clinical and electrophysiological studies revealed that nine[…][ncbi.nlm.nih.gov]

    Missing: Variable Psychomotor Retardation
  • Juvenile Myoclonic Epilepsy

    Juvenile myoclonic epilepsy is a common form of epilepsy mainly characterized by myoclonic jerks, but affected individuals may also experience generalized tonic-clonic seizures and absence seizures. Symptom onset typically occurs around puberty and although the disease persists into adulthood, patients do respond[…][symptoma.com]

    Missing: Variable Psychomotor Retardation
  • Idiopathic Generalized Epilepsy

    Tonic status epilepticus (TSE) in patients with idiopathic generalized epilepsy (IGE) is not well recognized. The objective of this study is to report episodes of TSE in patients with IGE. We retrospectively reviewed the clinical and EEG evaluation of three IGE patients who presented TSE. The three patients had mainly[…][ncbi.nlm.nih.gov]

    Missing: Variable Psychomotor Retardation
  • Juvenile Absence Epilepsy

    PURPOSE: The aim of this study to evaluate the hippocampal, frontal and thalamic lobe functions in the early stage of the juvenile absence epilepsy (JAE) by magnetic resonance proton spectroscopy (MRS). METHOD: Fourteen patients with juvenile absence epilepsy with typical absence seizures and 10 healthy volunteer[…][ncbi.nlm.nih.gov]

    Missing: Variable Psychomotor Retardation
  • Lennox-Gastaut Syndrome

    We did not include patients with interictal electrographic activity characterized by multifocal spikes, focal delta activity different to delta with maximum in the frontal[omicsonline.org] […] region that typically differentiates LGS from severe epilepsy with multiple independent spikes foci.[omicsonline.org]

    Missing: Variable Psychomotor Retardation
  • Early Infantile Epileptic Encephalopathy Type 3

    Epileptic encephalopathy with suppression-burst in electroencephalography (EEG) can evolve into a few types of epileptic syndromes. We present here an unusual case of early myoclonic encephalopathy that evolved into migrating partial seizures in infancy. A female neonate initially had erratic myoclonus movements,[…][ncbi.nlm.nih.gov]

    Missing: Variable Psychomotor Retardation