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142 Possible Causes for Multifocal Spikes

  • Early Myoclonic Encephalopathy

    The EEG pattern often shows a suppression-burst pattern with high-voltage bursts of slow waves mixed with multifocal spikes alternating with isoelectric suppression phases[diseaseinfosearch.org] West Syndrome (WS) aka as infantile spasms with hypsarrhythmia, EEG abnormality with asynchronous very high amplitude, irregular, continuous multifocal spike an slow wave[ijponline.biomedcentral.com] ., multifocal spike- and sharp-wave discharges, repetitive paroxysmal activity, unusually low-voltage fast activity, and findings consistent with complex partial seizures[graphyonline.com]

  • West Syndrome

    Interictal The background EEG is often highly disorganized with high voltage irregular slow waves intermixed with multifocal spikes and polyspikes, this is termed 'hypsarrhythmia[epilepsydiagnosis.org] The interictal EEG pattern is described as hypsarrhythmic as it is characterised by asynchronous and high-amplitude slow waves and multifocal spikes.[orpha.net] Hypsarrhythmia is a characteristic interictal pattern of chaotic, high to extremely high-voltage polymorphic delta and theta rhythms with superimposed multifocal spikes and[patient.info]

  • Epilepsy

    Electroencephalography showed multifocal spikes over the right frontal, temporal and parietal regions. The seizure frequency decreased dramatically after tumorectomy.[ncbi.nlm.nih.gov]

  • Lennox-Gastaut Syndrome

    We did not include patients with interictal electrographic activity characterized by multifocal spikes, focal delta activity different to delta with maximum in the frontal[omicsonline.org] Interictal EEG showed findings characteristic of LGS: generalized slow spike-wave complexes, multifocal sharp waves, generalized polyspikes and paroxysmal fast activity during[ncbi.nlm.nih.gov]

  • Myoclonic-Astatic Epilepsy

    ; LTG, lamotrigine; M, myoclonic seizure; MA, myoclonic-astatic seizure; MF, multifocal spikes; PHT, phenytoin; PSW, diffuse polyspike and wave complexes; SBA, slowing of[omicsonline.org] Interictal EEG revealed generalized irregular multiple spikes-and-waves with focal or multifocal accentuations.[ncbi.nlm.nih.gov] […] and waves, photosensitivity, 4-7/sec rhythms), no multifocal EEG abnormalities (but often pseudofoci).[ncbi.nlm.nih.gov]

  • Early Infantile Epileptic Encephalopathy 13

    Diagnosis Hypsarrhythmia, the typical interictal EEG finding, consists of a disorganized pattern with asynchronous, very high amplitude slowing and frequent multifocal spike[intechopen.com] Diagnosis The interictal EEG consists of multifocal epileptiform discharges and background slowing.[intechopen.com] Ictal EEG recording may demonstrate generalized slow spike and wave, or an absence pattern, depending on the seizure type. 8.3.[intechopen.com]

  • Familial Progressive Myoclonic Epilepsy

    Cortical myoclonus is more commonly encountered in a multifocal form, presenting with multifocal spike discharges.[neupsykey.com] multifocal abnormalities.[neupsykey.com] Paroxysmally, rhythmic θ-activity at 4 to 5 Hz appears in the centroparietal areas, as do fast bilateral spike-waves, which may be associated later with variable focal or[neupsykey.com]

  • Benign Adult Familial Myoclonic Epilepsy

    Note the high-amplitude, disorganized slow activity with multifocal spikes with an electrodecremental response.[euroformhealthcare.biz] Cortical myoclonus is more commonly encountered in a multifocal form, presenting with multifocal spike discharges.[neupsykey.com] […] with emesis.  Interictal EEG with shifting or multifocal high- amplitude spikes, often with occipital predominance.  Favorable outcome with remission in 1–2 years and normal[slideshare.net]

  • Juvenile Absence Epilepsy

    Background activity is often abnormal, reflecting the diffuse or multifocal underlying encephalopathy of symptomatic generalized epilepsy.[reference.medscape.com] Slow spike-and-wave discharges (2.5 Hz). This is an interictal pattern in a child with seizures and developmental delay.[reference.medscape.com] The clinical correlation of generalized spike-and-wave complexes with clinical seizures is not as clear-cut as in typical absence seizures.[reference.medscape.com]

  • Hypoxic-Ischemic Encephalopathy

    Tau protein is s specific protein expressed by neurons in the central nervous system. Elevated serum Tau protein is associated with many diseases of the central nervous system. The serum Tau protein level in neonates with hypoxic ischemic encephalopathy (HIE) is still poorly understood. Forty-one human neonates[…][ncbi.nlm.nih.gov]

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