Multifocal Spikes Causes & Reasons

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Multifocal Spikes Symptom Checker: Possible causes include Epilepsy. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Epilepsy

[…] predominance, and multifocal spike-and-slow waves. [ncbi.nlm.nih.gov]

Electroencephalography showed multifocal spikes over the right frontal, temporal and parietal regions. The seizure frequency decreased dramatically after tumorectomy. [ncbi.nlm.nih.gov]

Inter-ictal multifocal spikes or sharp and slow waves in nearly all EEGs. [epilepsy.com]

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West Syndrome

Interictal The background EEG is often highly disorganized with high voltage irregular slow waves intermixed with multifocal spikes and polyspikes, this is termed 'hypsarrhythmia [epilepsydiagnosis.org]

The interictal EEG pattern is described as hypsarrhythmic as it is characterised by asynchronous and high-amplitude slow waves and multifocal spikes. [orpha.net]

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Benign Adult Familial Myoclonic Epilepsy

Note the high-amplitude, disorganized slow activity with multifocal spikes with an electrodecremental response. [euroformhealthcare.biz]

Cortical myoclonus is more commonly encountered in a multifocal form, presenting with multifocal spike discharges. [neupsykey.com]

[…] with emesis.  Interictal EEG with shifting or multifocal high- amplitude spikes, often with occipital predominance.  Favorable outcome with remission in 1–2 years and normal [slideshare.net]

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Myoclonic-Astatic Epilepsy

Interictal EEG revealed generalized irregular multiple spikes-and-waves with focal or multifocal accentuations. [ncbi.nlm.nih.gov]

LTG, lamotrigine; M, myoclonic seizure; MA, myoclonic-astatic seizure; MF, multifocal spikes; PHT, phenytoin; PSW, diffuse polyspike and wave complexes; SBA, slowing of [omicsonline.org]

[…] and waves, photosensitivity, 4-7/sec rhythms), no multifocal EEG abnormalities (but often pseudofoci). [ncbi.nlm.nih.gov]

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Idiopathic Generalized Epilepsy

spikes and slow waves Ictal EEG: very heterogeneous First-line treatment: ACTH, prednisone, or vigabatrin Poor; increased mortality Neurodevelopmental delay, regression of [amboss.com]

The interictal EEG showed generalized spike-and-wave alone in 8 patients, focal or multifocal spike-and-wave alone in 3 patients, both generalized and focal spike-and-wave [nature.com]

[…] sharp and slow waves Abnormal interictal EEG: slow spike-wave pattern Attempt anticonvulsive treatment, e.g., valproic acid, clobazam, lamotrigine, felbamate [13] Ketogenic [amboss.com]

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Generalized Clonic or Tonic-Clonic Seizures

‘Contrary to popular folk belief, nothing should be placed in the mouth during the seizure. Severe injury could occur.’ Generalized tonic clonic seizures (grand mal seizures) are the most common and best known type of generalized seizure. They begin with stiffening of the limbs (the tonic phase), followed by jerking[…] [epilepsynw.org]

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Juvenile Myoclonic Epilepsy

We present a case of a boy with juvenile myoclonic epilepsy (JME) who presented with features of non-convulsive status epilepticus (NCSE). This case highlights the fact that NCSE, even though not a common occurrence in JME, should be kept in mind when a patient with previous history of seizures presents with[…] [ncbi.nlm.nih.gov]

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Early Infantile Epileptic Encephalopathy Type 17

@inproceedings{Kehrl2014GainoffunctionMI, title {Gain-of-function mutation in Gnao1: A murine model of epileptiform encephalopathy (EIEE17)?}, author {Jason M. Kehrl and Kinshuk Sahaya and Hans M. Dalton and Raelene A. Charbeneau and Kevin T. Kohut and Kristen A Gilbert and Madeline C. Pelz and Jack M. Parent and[…] [semanticscholar.org]

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Juvenile Absence Epilepsy

Background activity is often abnormal, reflecting the diffuse or multifocal underlying encephalopathy of symptomatic generalized epilepsy. [reference.medscape.com]

Slow spike-and-wave discharges (2.5 Hz). This is an interictal pattern in a child with seizures and developmental delay. [reference.medscape.com]

The clinical correlation of generalized spike-and-wave complexes with clinical seizures is not as clear-cut as in typical absence seizures. [reference.medscape.com]

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Panayiotopoulos Syndrome

Interictal EEG showed multifocal spikes in the centrotemporal and left posterior regions. [ncbi.nlm.nih.gov]

Interictal EEG shows occipital spikes although multifocal spikes with high amplitude sharp-slow wave complexes at various locations can be present. [ncbi.nlm.nih.gov]

spikes. [ncbi.nlm.nih.gov]

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Organic Brain Syndrome

Rogers MP, et al. Psychosom Med. 1986 Jul-Aug. Abstract Systemic mastocytosis is a disease characterized by an excessive accumulation of mast cells, and associated with skin lesions, flushing, diarrhea, tachycardia, and psychiatric manifestations. In order to define more clearly the psychiatric manifestations, ten[…] [ncbi.nlm.nih.gov]

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Encephalopathy

Posterior reversible encephalopathy syndrome is an encephalopathy that can be clinically characterized by headache, altered mental status and/or seizures. Neuroimaging demonstrates usually reversible bilateral subcortical vasogenic occipital-parietal edema. Exact pathophysiology remains unclear but is commonly[…] [ncbi.nlm.nih.gov]

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Uremic Encephalopathy

BACKGROUND AND PURPOSE: Uremic encephalopathy is a metabolic disorder in patients with renal failure. The purpose of this study was to describe the MR imaging findings of uremic encephalopathy. MATERIALS AND METHODS: This study retrospectively reviewed MR imaging findings in 10 patients with clinically proved uremic[…] [ncbi.nlm.nih.gov]

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Early Infantile Epileptic Encephalopathy Type 3

The EEG pattern often shows a suppression-burst pattern with high-voltage bursts of slow waves mixed with multifocal spikes alternating with isoelectric suppression phases [diseaseinfosearch.org]

West Syndrome (WS) aka as infantile spasms with hypsarrhythmia, EEG abnormality with asynchronous very high amplitude, irregular, continuous multifocal spike an slow wave [ijponline.biomedcentral.com]

multifocal spike- and sharp-wave discharges, repetitive paroxysmal activity, unusually low-voltage fast activity, and findings consistent with complex partial seizures [graphyonline.com]

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Lennox-Gastaut Syndrome

Interictal There may be focal or multifocal spike-and-wave or sharp-slow waves, with an anterior predominance. [epilepsydiagnosis.org]

Electroencephalogram (EEG) showed background slowing of about 7 Hz, multifocal spike and wave, and generalized spike and wave complex-es (1.5 3.5 Hz). [jkna.org]

The interictal EEG record was suggestive of multifocal spike-and-wave discharges in both hemispheres, particularly in the left frontocentral, right parieto-temporo-occipital [pediatricneurosciences.com]

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Insulin Overdose

We report a very rare case of acute pulmonary edema caused by hypoglycemia from insulin overdose during an attempted suicide. A 16-year-old woman with type 1 diabetes was brought to our hospital because of hypoglycemic coma. She exhibited severe hypoxia; upon intubation, bloody froth poured out of the tube.[…] [ncbi.nlm.nih.gov]

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Toxic Encephalopathy

Neurotoxicity following paradichlorobenzene (PDCB) exposure is rare and can occur in patients with pica and mothball or toilet cake ingestion. We present a rare case of toxic encephalopathy due to PDCB mothball inhalation and ingestion and describe the rapidly progressive leukoencephalopathy seen on computed[…] [ncbi.nlm.nih.gov]

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Hypoxic-Ischemic Brain Injury

Brain Dev. 2015 Feb;37(2):265-9. doi: 10.1016/j.braindev.2014.04.002. Epub 2014 Apr 29. Author information 1 Department of Pediatrics, Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan. Electronic address: pisces-koya@yacht.ocn.ne.jp. 2 Department of Neuromuscular Research, National Institute of Neuroscience, National[…] [ncbi.nlm.nih.gov]

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Progressive Myoclonic Epilepsy Type 8

[…] fast spikes, polyspikes and polyspike‐and‐wave discharges Slow background activity, spike‐ and polyspike‐and‐wave discharges and multifocal spikes activated by non‐REM sleep [onlinelibrary.wiley.com]

Slow background activity mixed with low‐voltage fast activity, along with diffuse, irregular, spike‐ and polyspike‐and‐wave discharges Slow background activity and multifocal [onlinelibrary.wiley.com]

spike and polyspike‐and‐wave discharges. [onlinelibrary.wiley.com]

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Focal Epilepsy - Speech Disorder - Mental Retardation

Multifocal Spike and Wave is defined as "spikes in 3 non-contiguous electrode positions with at least one focus in each hemisphere" (Blume 1982). [pediatrics.emory.edu]

Note the high-amplitude, disorganized slow activity with multifocal spikes with an electrodecremental response. [euroformhealthcare.biz]

During the awake and light sleep states, the EEG was abnormal in most of the patients (9/ 11) with multifocal spikes. [scielo.br]

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Pyridoxine Dependency Syndrome

Hypsarrhythmia is a characteristic interictal pattern of chaotic, high to extremely high-voltage polymorphic delta and theta rhythms with superimposed multifocal spikes and [patient.info]

[…] myoclonic Malignant migrating partial seizures of infancy Multifocal sharps Focal, arising from multiple regions Pyridoxine-dependent epilepsy Continuous spike-wave Burst [demosmedical.com]

Patients with West syndrome associated with HME may have a unique EEG background called hemihypsarrhythmia (high amplitude, poorly organized with multifocal spikes over the [demosmedical.com]

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Febrile Infection-Related Epilepsy Syndrome

[…] to multifocal spikes on EEG, that did not respond to antiepileptics (phenobarbital, midazolam, phenytoin, topiramate, levetiracetam, lacosamide, thiopental (burst suppression [thieme-connect.com]

Results: Following an upper respiratory tract infection, this previously healthy 3-year-old girl developed generalized tonic-clonic and multifocal myoclonic seizures, corresponding [thieme-connect.com]

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Early Infantile Epileptic Encephalopathy Type 6

As seizures accumulate, however, multifocal spikes or spike and waves are encountered on EEG. [symptoma.com]

Among the 31 adult patients reported by Akiyama et al. (2010), 4 (12.9%) had generalized spike‐waves and multifocal spikes, 13 (41.9%) had multifocal spikes, 6 (19.3%) had [onlinelibrary.wiley.com]

Patterns can include generalized spike and wave discharges, multiple spike and wave discharges, and multifocal spikes 1. [centogene.com]

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Atypical Absence Seizure

Diffuse slowing and focal or multifocal spikes or sharp waves were seen in 85%. [epilepsy.com]

Background activity is often abnormal, reflecting the diffuse or multifocal underlying encephalopathy of symptomatic generalized epilepsy. [reference.medscape.com]

Slow spike-and-wave discharges (2.5 Hz). This is an interictal pattern in a child with seizures and developmental delay. [reference.medscape.com]

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Unverricht-Lundborg Syndrome

Beyond early childhood and almost regardless of etiology, the typical EEG of SGE includes slow ( 2.5 Hz) spike and wave complexes and multifocal spikes. [emedicine.medscape.com]

At the beginning, three patients (patients 13, 14, and 16) showed multifocal spikes, which were still present in the last EEG. [onlinelibrary.wiley.com]

[…] waves 1.5–2.5 Hz or multifocal Absence-low spike and waves; tonic-generalized attenuation with recruiting rhythm; atonic-generalized polyspike/spike waves, or attenuation [hindawi.com]

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Vitiligo

The interictal EEG pattern is described as hypsarrhythmic as it is characterised by asynchronous and high-amplitude slow waves and multifocal spikes. [orpha.net]

Hypsarrhythmia is a characteristic interictal pattern of chaotic, high to extremely high-voltage polymorphic delta and theta rhythms with superimposed multifocal spikes and [patient.info]

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Familial Infantile Myoclonic Epilepsy

The EEG typically shows focal or multifocal spike-waves, sharp waves, and slow waves and spikes activity [88]. [ijponline.biomedcentral.com]

Over time, the interictal EEG can show both generalized and multifocal spikes, or may not show any of these features despite frequent seizures of multiple types, further highlighting [clinicalgate.com]

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Joint Dislocation

The interictal EEG pattern is described as hypsarrhythmic as it is characterised by asynchronous and high-amplitude slow waves and multifocal spikes. [orpha.net]

Hypsarrhythmia is a characteristic interictal pattern of chaotic, high to extremely high-voltage polymorphic delta and theta rhythms with superimposed multifocal spikes and [patient.info]

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Lafora Disease

Electroencephalogram (EEG) showed bilateral diffuse low voltage, delta waves slowing with frequent generalized, multifocal spike discharges. [ijdvl.com]

The EEG register is slow in background activity and presents multifocal paroxystic discharges of spike and spike waves. [jnnp.bmj.com]

Electroencephalogram (EEG) findings in LBD may include multiple spikes and wave discharges, photosensitivity, multifocal epileptiform discharges, and progressive slowing in [annalsofian.org]

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Generalized Motor Seizure

(A) Slow spike-and-waves and (B) multifocal independent spike discharges in two patients with GMS and mixed tonic, tonic–clonic, and myoclonic seizures. (From Tatum WO. [neupsykey.com]

In most patients with GTS associated with EGE, a diffusely slow background with multifocal spikes and sharp waves (Figure 14.7b) is present on the EEG reflecting a diffuse [neupsykey.com]

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