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159 Possible Causes for Multifocal White Matter Lesions

  • Jacobsen Syndrome

    Conclusion: Facing multifocal white matter lesions, rare genetic causes must be taken into consideration in addition to metabolic causes.[] ", number "4", } TY - JOUR T1 - A case of Jacobsen syndrome with multifocal white matter lesions AU - Yu, Fang AU - Carter, John E AU - Bazan Iii, Carlos PY - 2016/7/1 Y1[] In magnetic resonance imaging of the head both patients showed multifocal white matter lesions; in patient 1 particularly subcortical, in patient 2 periventricular in the[]

  • Vitamin B12 Deficiency

    […] vacuolated and demyelinating lesions in the white matter and in the posterior and lateral columns.[] […] to describe the pathological process seen in vitamin B12 deficiency; macroscopically the cord is shrunken in the anteroposterior diameter while microscopically there are multifocal[]

  • Anemia

    Microscopic: Multifocal vacuolated and demyelinated lesions exist in the white matter of the posterior and lateral columns.[] The posterior and lateral columns may be gray-white in color.[]

  • Susac Syndrome

    Results: All 27 patients had multifocal supratentorial white matter lesions including the corpus callosum.[]

  • Other Specified Degenerative Diseases of the Nervous System

    […] involving the thalami, brainstem, cerebellum, and white matter.[] , cerebellum and white matter.[] The hallmark of this encephalopathy is multifocal, symmetric brain lesions affecting the bilateral thalamus, brainstem tegmentum, cerebral periventricular white matter and[]

  • Hypertensive Crisis

    Once blood pressure was controlled and indinavir replaced by nelfinavir, white matter lesions at magnetic resonance imaging disappeared.[] The clinical and radiologic evolution excludes other diagnosis as progressive multifocal leukoencephalopathy and points indinavir as a potential hypertension-inducing agent[]

  • Medial Sclerosis

    Multifocal white matter disease of MS is easily observed but not easily differentiated from vascular lesions, gliotic scars or other forms of inflammation (see Chap. 11 ).[]

  • Acute Disseminated Encephalomyelitis

    Acute disseminated encephalomyelitis (ADEM) is an acute demyelinating disorder of the central nervous system, and is characterised by multifocal white matter involvement.[] The typical computed tomographic appearance is that of low attenuation, multifocal lesions in the subcortical white matter.[] Diffuse neurological signs along with multifocal lesions in brain and spinal cord characterise the disease.[]

  • Progressive Multifocal Leukoencephalopathy

    Brain magnetic resonance imaging showed asymmetric multifocal white matter lesions without contrast enhancement.[] Although typically characterized by multifocal asymmetric subcortical white matter lesions, it may be monofocal and affect the cortical gray matter.[] matter lesions on brain magnetic resonance imaging (MRI).[]

  • Demyelinating Disease

    A very characteristic MRI pattern is seen, however, with nonenhancing multifocal lesions in the subcortical white matter. The neuropathological changes are unique.[] The clinical symptoms are frequently non-specific such as headaches, fever, and lethargy, while MRI detects widespread, multifocal, and extensive white and deep gray matter[] Rarely, in patients with AIDS, varicella‐zoster virus causes multifocal lesions in the cerebral white matter that are partly demyelinating. 41 Viral inclusions and antigen[]

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