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11 Possible Causes for Multiple Congenital Anomalies, Nausea, Wide Space Between the First and Second Toe

  • Down Syndrome

    A 35-year-old female patient had visited another hospital for 1 month for abdominal discomfort, nausea, constipation, and palpable mass.[ncbi.nlm.nih.gov] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] The most commonly reported side effects were "diarrhoea, fatigue, insomnia, nausea and vomiting" (page 497; Prasher 2005 ).[doi.org]

  • Dubowitz Syndrome

    Likewise, the diarrhea and nausea can be treated with over-the-counter medications, and the hyperactivity may be treated with prescription drugs, in some cases.[wisegeek.net] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] This group will include 50% with chromosomal disorders congenital anomaly syndromes, especially recognizable by performing a karyotype, the details about their features and[books.google.com]

  • Russell-Silver Syndrome

    These infrequent/rare side effects include the following: mild transient hypoglycemia; injection site reactions such as rashes; transient headaches, nausea and/or vomiting[magicfoundation.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] congenital anomalies/dysmorphic syndrome-variable intellectual disability syndrome, malformation syndrome with short stature, polymalformative genetic syndrome with increased[commons.wikimedia.org]

  • Kleiner Holmes Syndrome

    THE ESOPHAGUS Is also known as escc; esophageal epidermoid carcinoma; esophageal squamous cell carcinoma Related symptoms: Feeding difficulties in infancy Lymphadenopathy Nausea[mendelian.co] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov] However, chromosomal studies are probably warranted in any child with scalp aplasia cutis congenita associated with multiple congenital anomalies when a specific syndrome[annsaudimed.net]

  • Cutis Laxa

    CASE PRESENTATION A 50-year-old female with history of CL diagnosed in 1991, presented to emergency room with complaints of nausea, vomiting and abdominal distension.[academic.oup.com] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] Abstract The autosomal dominant progeroid form of cutis laxa is a recently identified multiple congenital anomaly disorder characterized by thin, wrinkled skin, a progeroid[ncbi.nlm.nih.gov]

  • Familial Congenital Nasolacrimal Duct Obstruction

    […] bleeding (1) Hepatitis (4) Hepatitis A (2) Hepatitis B (2) Hepatitis C (7) Hepatotoxicity (1) Intestinal obstruction (1) Irritable bowel syndrome (1) Lactose intolerance (1) Nausea[innovations.ahrq.gov] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] Multiple congenital anomalies-hypotonia-seizures syndrome type 2 Multiple congenital anomalies-hypotonia-seizures syndrome type 3 Multiple congenital anomalies-intellectual[orpha.net]

  • Weaver Syndrome

    Any-grade AEs reported in more than 5% of patients included nausea (20%), thrombocytopenia (19%), cough (14%), diarrhea (11%), fatigue (12%), and asthenia (10%).[targetedonc.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Schinzel–Giedion Syndrome Individuals with Schinzel–Giedion syndrome (SGS) have severe developmental delay, distinctive facial features, and multiple congenital anomalies[clincancerres.aacrjournals.org]

  • MORM Syndrome

    Pregnant women developing HELLP syndrome have reported experiencing one or more of these symptoms: Headache Nausea/vomiting/indigestion with pain after eating Abdominal or[preeclampsia.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] chemical sensitivity multiple congenital anomalies-hypotonia-seizures syndrome Multiple Congenital Anomalies/Dysmorphic Syndrome-Intellectual Disability Multiple Hamartoma[rgd.mcw.edu]

  • Tricho-Oculo-Dermo-Vertebral Syndrome

    Headache, blurring or dimness of vision, and sometimes dizziness or nausea may also occur. Anatomic features of the eye.[medical-dictionary.thefreedictionary.com] space between the first and second toes, and fusion of carpal and tarsal bones.[findzebra.com] […] newborn neg - negative NG - nasogastric nil - none no - number NO - nursing office NPN - nonprotein nitrogen NPO - nothing by mouth N/S - normal saline nsy - nursery N/V - nausea[hopperinstitute.com]

  • Acrofacial Dysostosis Type Catania

    Colic, cramps, toothache, blood clots, fever, nausea, high cholesterol, heart disease, stomach ulcers, heartburn, irritable bowel syndrome, migraine headache, allergic rhinitis[waittfoundation.org] He had a wide space between the first and second toe of his feet and subungual fibroma on the second and third toe of the right foot and on the third toe of the left foot.[jmg.bmj.com] 604315 Anemia, Congenital Hypoplastic, with Multiple Congenital Anomalies/Mental Retardation Syndrome OMIM:206100 Anemia, Hypochromic Microcytic, with Iron Overload 1; AHMIO1[informatics.jax.org]

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