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59 Possible Causes for Multiple Myeloma, Pancytopenia, Visual Hallucination

  • Multiple Myeloma

    Haematological tests revealed severe anaemia with pancytopenia, which prompted further investigations including a bone marrow biopsy confirming a diagnosis of multiple myeloma[ncbi.nlm.nih.gov] Leukemia, lymphoma and multiple myeloma, 1950–1987 . Radiat. Res. 137 , S68–S97 (1994). 18. Khuder, S. A. & Mutgi, A. B. Meta-analyses of multiple myeloma and farming .[doi.org] Marrow function becomes increasingly compromised as patients develop pancytopenia and enter a refractory phase; occasionally, the myeloma cells dedifferentiate and extramedullary[cancer.gov]

  • Pernicious Anemia

    The outcome was rapidly marked by febrile pancytopenia and ataxia leading to the diagnosis of pernicious anemia.[ncbi.nlm.nih.gov] Other causes include leukemia , myelofibrosis , multiple myeloma, certain hereditary disorders, drugs that affect nucleic acid metabolism such as chemotherapy agents (methotrexate[diagnose-me.com] hallucinations the so called megaloblastic madness have been described with vitamin B-12 deficiency.[ispub.com]

  • Megaloblastic Anemia

    We hypothesize that promoter variants in the inducible nitric oxide synthase gene might be the cause of severe refractory megaloblastic anemia and pancytopenia in our patient[ncbi.nlm.nih.gov] It can also be caused by leukemia, multiple myeloma, certain hereditary disorders, and some chemotherapy agents.[ecgastro.com] Neuropsychiatric manifestation include memory loss, depression, hypomania, paranoid psychosis with auditory and visual hallucinations.[allaboutblood.com]

  • Lupus Cerebritis

    The patient’s admission labs were notable for pancytopenia and normal renal function and urine sediment.[utswim.wordpress.com] Myeloma 798 Parkinson Disease 802 Munchausen Syndrome 804 Myocardial Contusion 810 Neck Injury by StrangulationHanging 818 Penile Shaft Fracture 820 Sting 822 Necrotizing[books.google.ro] Hallucinations, such as Sheila also experienced are another common psychiatric manifestation of lupus and the brain.[lupusinternational.com]

  • Chlorambucil

    Overdose and treatment Evidence of overdose includes reversible pancytopenia in adults, and vomiting, ataxia, abdominal pain, muscle twitching, and major motor seizures.[glowm.com] , klȯr- \ Medical Definition of chlorambucil : an anticancer drug C 14 H 19 Cl 2 NO 2 that is a derivative of nitrogen mustard and is used especially to treat leukemias, multiple[merriam-webster.com] Some reports do exist of nerve damage that has resulted in seizures, muscle twitching, muscle shaking, confusion, visual hallucinations, irritability, and loss of muscle control[encyclopedia.com]

  • Ifosfamide

    Eight days after the 3rd cycle of IFO, the patient was admitted for sepsis, lung infection, pancytopenia (1,400 leukocytes, 1,200 neutrophils, hemoglobin 8.2 g/dl, and 13,000[karger.com] Myeloma D009101 EFO:0001378 multiple myeloma 1 ClinicalTrials Neoplasms D009369 EFO:0000311 cancer 1 ClinicalTrials Neoplasms D009369 EFO:0000616 neoplasm 1 ClinicalTrials[ebi.ac.uk] Encephalopathy is manifested by cerebellar ataxia, confusional state, complex visual hallucinations, extrapyramidal signs, seizures, and mutism.[ncbi.nlm.nih.gov]

  • Chloroquine

    Hematologic system: Rarely, pancytopenia, aplastic anemia, reversible agranulocytosis, thrombocytopenia and neutropenia.[dailymed.nlm.nih.gov] The proteasome inhibitor bortezomib is now the cornerstone of combination therapy of multiple myeloma (MM).[ncbi.nlm.nih.gov] Chloroquine may cause blood disorders like pancytopenia and agranulocytosis. Chloroquine may affect the eyes causing retinopathy, diplopia and blurring of vision.[webhealthcentre.com]

  • Alcohol Hallucinosis

    Investigations may reveal a pancytopenia as a result of ethanol-induced bone marrow toxicity. Folate deficiency is common.[academic.oup.com] ., multiple myeloma , ependymomas , astrocytomas , metastases ) and intradural-extramedullary (e.g., meningiomas , nerve sheath tumors) History of cancer (e.g., lung cancer[amboss.com] Brust First published July 1, 1984, DOI: Abstract During alcohol withdrawal, a man totally blind following ocular trauma experienced formed visual hallucinations (“alcoholic[neurology.org]

  • Meningitis

    Laboratory tests may reveal pancytopenia and elevated levels of hepatic transaminases, blood urea nitrogen (BUN), and creatinine.[emedicine.medscape.com] Patients with the following conditions are at increased risk for S pneumoniae meningitis: Hyposplenism Hypogammaglobulinemia Multiple myeloma Glucocorticoid treatment Defective[emedicine.medscape.com] Visual hallucinations have been especially problematic in patients treated in this outbreak and appear to be related to high serum levels.[dx.doi.org]

  • Fluorouracil

    Because of pancytopenia, DPYD enzyme activity could not be assessed in patient 2; genotypic analysis of DPYD during autopsy revealed the presence of the heterozygous mutation[ncbi.nlm.nih.gov] Myeloma D009101 EFO:0001378 multiple myeloma 1 ClinicalTrials Carcinoma, Renal Cell D002292 EFO:0000681 renal cell carcinoma 3 ClinicalTrials Cholangiocarcinoma D018281 EFO[ebi.ac.uk] There was no evidence of auditory or visual hallucinations. Her neurological examination was normal.[doi.org]

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