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27 Possible Causes for Multiple Sclerosis-Like Illness, Optic Disc Pallor

  • Leber's Hereditary Optic Neuropathy

    It is suggested that multiple sclerosis-like illness and deformities of the vertebral column may be associated pathogenically with Leber's hereditary optic neuropathy.[ncbi.nlm.nih.gov] Fundoscopic examination showed hyperemic papilla on the right eye and optic disc pallor on the left eye.[ncbi.nlm.nih.gov] It is suggested that various movement disorders, multiple sclerosis-like illness, and deformities of the vertebral column may associate pathogenetically with LHON.[ncbi.nlm.nih.gov]

  • Optic Atrophy

    sclerosis-like illness, spastic paraplegia or cataracts.[ncbi.nlm.nih.gov] CONCLUSIONS: Deeply buried ODD may be associated with NAION causing irreversible visual loss and optic disc pallor, a condition easily mistaken for atypical ON.[ncbi.nlm.nih.gov] Other manifestations have been more rarely associated with ADOA plus, such as multiple sclerosis-like illness, migraine, cardiomyopathy, late-onset diabetes mellitus, and[orpha.net]

  • Autosomal Dominant Optic Atrophy

    Other manifestations have been more rarely associated with ADOA plus, such as multiple sclerosis-like illness, migraine, cardiomyopathy, late-onset diabetes mellitus, and[orpha.net] These patients typically present in the first decade of life with slightly subnormal acuity, dyschromatopsia, central visual field loss, and optic disc pallor.[practicalreviews.com] Other patients have minor neurologic abnormalities, such as a postural tremor, loss of ankle reflexes, dystonia, spasticity, or a multiple sclerosislike illness.[merckmanuals.com]

  • Retrobulbar Neuritis

    […] event but does not always occur Multiple Sclerosis-up to 75% of patients with CDMS will have at least one episode of optic neuritis in their lifetime.[eyewiki.aao.org] disc pallor and/or optic disc swelling relative afferent pupillary defect detected by the swinging light test in the affected eye, the pupil will dilate with direct illumination[medbullets.com] Loss of colour vision and optic disc pallor are commonly found in asymptomatic patients with dominant optic atrophy.[doi.org]

  • Primary Optic Atrophy

    Other patients have minor neurologic abnormalities, such as a postural tremor, loss of ankle reflexes, dystonia, spasticity, or a multiple sclerosislike illness.[merckmanuals.com] Optic disc pallor is one of the defining characteristics of Dominant Optic Atropy.[webeye.ophth.uiowa.edu] F igure 1. ( A ) Right optic disc of patient 6 with diffuse pallor and nerve fiber layer loss. ( B ) Left optic disc of patient 14 with wedge-shaped temporal pallor reminiscent[iovs.arvojournals.org]

  • Autosomal Recessive Spastic Paraplegia Type 46

    sclerosis-like illness, spastic paraplegia or cataracts.[ncbi.nlm.nih.gov] The ophthalmic examination discloses on fundoscopy isolated optic disc pallor or atrophy, related to the RGC death.[ncbi.nlm.nih.gov] […] extraocular multi-systemic features, including neurosensory hearing loss, or less commonly chronic progressive external ophthalmoplegia, myopathy, peripheral neuropathy, multiple[ncbi.nlm.nih.gov]

  • Autosomal Dominant Optic Atrophy and Cataract

    Other patients have minor neurologic abnormalities, such as a postural tremor, loss of ankle reflexes, dystonia, spasticity, or a multiple sclerosislike illness.[merckmanuals.com] Optic disc pallor is one of the defining characteristics of Dominant Optic Atropy.[webeye.ophth.uiowa.edu] Some individuals with LHON, usually women, also have a multiple sclerosis (MS)-like illness. LHON is transmitted by maternal inheritance.[ncbi.nlm.nih.gov]

  • Optic Neuropathy

    Some females have a multiple sclerosis-like neurologic illness. Genetics This disorder results from mutations in mitochondrial genes.[disorders.eyes.arizona.edu] Two months later, VA was 20/20 OD and hand motions OS, with relative afferent pupillary defect and a pallor of the optic disc in OS.[ncbi.nlm.nih.gov] Optic discs: are initially normal but may develop mild temporal disc pallor if ethambutol is continued.[epomedicine.com]

  • Optic Papillitis

    […] event but does not always occur Multiple Sclerosis-up to 75% of patients with CDMS will have at least one episode of optic neuritis in their lifetime.[eyewiki.aao.org] Normal or swollen optic disc; disc pallor occurs later (4-6 weeks after onset). Visual field defect - any type. Normal macula and peripheral retina.[patient.info] Right fundus showed mild disc pallor with full cup and blurred margins suggestive of papillitis developing secondary optic atrophy [Figure - 1].[ijo.in]

  • Multiple Sclerosis

    Other multifocal illnesses or white-matter diseases are seldom confused with multiple sclerosis.[dx.doi.org] The evolution of temporal optic disc pallor (arrow) after left optic neuritis.[emedicine.com] Occurrence of a multiple sclerosis-like illness in women who have a Leber's hereditary optic neuropathy mitochondrial DNA mutation.[ncbi.nlm.nih.gov]

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