Muscle Biopsy showing Inclusion Bodies Causes & Reasons

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Muscle Biopsy showing Inclusion Bodies Symptom Checker: Possible causes include Inclusion Body Myositis. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Patient File

Sex unknown, Age unknown

Reported Symptoms

Muscle Biopsy showing Inclusion Bodies,

Negated

None

Unsure

None

Possible Causes

Inclusion Body Myositis

We performed a muscle biopsy that showed inclusion body myositis (IBM). [ncbi.nlm.nih.gov]

A review of the previously performed muscle biopsy showed most of the cardinal myopathologic features of sporadic inclusion body myositis, in addition to the granuloma. [ncbi.nlm.nih.gov]

The muscle biopsy of inclusion body myositis shows mild to moderate inflammation, atrophic denervated fibers, and most characteristically "rimmed vacuoles" as well as some [bcm.edu]

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Labor

Although classified as an inflammatory myopathy, inclusion body myositis shows minimal evidence of inflammation. [emedicine.medscape.com]

Moreover, both conditions may be associated with malignancies. [5] Despite these similarities, muscle biopsy findings and characteristic skin findings of dermatomyositis reveal [emedicine.medscape.com]

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Birth

Although classified as an inflammatory myopathy, inclusion body myositis shows minimal evidence of inflammation. [emedicine.medscape.com]

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Puerperium

Although classified as an inflammatory myopathy, inclusion body myositis shows minimal evidence of inflammation. [emedicine.medscape.com]

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Radiculomyelopathy

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Granulomatous Myositis

A review of the previously performed muscle biopsy showed most of the cardinal myopathologic features of sporadic inclusion body myositis, in addition to the granuloma. [ncbi.nlm.nih.gov]

Muscle biopsy reveals inclusion bodies i.e. rimmed vacuoles formed due to the collection of abnormal proteins. [kenhub.com]

In inclusion body myositis, findings on muscle biopsy may show the presence of vacuolated muscle fibers with basophilic granular deposits, the presence of varying degrees [rheumatologyadvisor.com]

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Benign Adult Familial Myoclonic Epilepsy

The diagnosis is made by biopsy (skin, muscle, liver, brain) showing periodic acid-Schiff positive glycogen-like intracellular inclusion bodies (Lafora bodies). [neuroweb.us]

Brain MRI shows often cerebellar atrophy. [neuroweb.us]

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Celiac Disease

Muscle biopsy showed inflammatory changes in five. One patient had evidence of inclusion body myositis. [dx.doi.org]

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Myositis

Muscle biopsy reveals inclusion bodies i.e. rimmed vacuoles formed due to the collection of abnormal proteins. [kenhub.com]

Possible inclusion body myositis If the muscle shows only inflammation (invasion of nonnecrotic muscle fibers by mononuclear cells)—without other pathologic features of inclusion [ncbi.nlm.nih.gov]

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Distal Spinal Muscular Atrophy Type 5

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Amyotrophic Lateral Sclerosis Type 1

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Progressive Bulbar Paralysis

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Upper Motor Neuron Disease

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Motor Neuron Disease

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Amyotrophic Lateral Sclerosis

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Primary Lateral Sclerosis

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Bilateral Leg Weakness

Electromyography (EMG) and occasionally muscle biopsy are needed to confirm the diagnosis. Inclusion body myositis has a more benign prognosis than MND. [patient.info]

The list below shows further conditions that may have similar clinical features: Diabetic amyotrophy. Guillain-Barré syndrome. Post-polio syndrome. [patient.info]

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Inclusion Body Myopathy

The muscle biopsy of inclusion body myositis shows mild to moderate inflammation, atrophic denervated fibers, and most characteristically "rimmed vacuoles" as well as some [bcm.edu]

One sibling also showed PDB. Light and electron microscopy performed on muscle biopsies demonstrated degenerative changes with inclusion bodies and abnormal aggregates. [ncbi.nlm.nih.gov]

The clinical features and histological characteristics of the muscle biopsies showed the typical pattern of predominantly distal vacuolar myopathy with quadriceps sparing. [ncbi.nlm.nih.gov]

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Idiopathic Camptocormia

Thoracic paraspinal muscle biopsy showed canonical features of inclusion body myositis. [mayoclinic.pure.elsevier.com]

Thoracic paraspinal muscle biopsy showed canonical features of inclusion body myositis. The current patient broadens the clinical presentation of inclusion body myositis. [mayoclinic.pure.elsevier.com]

Neurologic examination revealed no limb weakness. magnetic resonance imaging studies showed atrophy and findings, suggesting fatty replacement of paraspinal muscles. [mayoclinic.pure.elsevier.com]

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Renal Injury

Although classified as an inflammatory myopathy, inclusion body myositis shows minimal evidence of inflammation. [emedicine.medscape.com]

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Adult Polyglucosan Body Disease

Some muscle biopsies show these inclusions in intramuscular nerve branches. [ncbi.nlm.nih.gov]

METHODS: Fifteen muscle biopsies from adults between the ages of 36 and 84 years, all showing polyglucosan bodies in intramuscular peripheral nerve twigs, were tested by sequencing [ncbi.nlm.nih.gov]

INTRODUCTION: Adult polyglucosan body disease (APBD) is associated with formation of polyglucosan bodies in peripheral nerve branches. [ncbi.nlm.nih.gov]

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Alcoholic Hepatitis

Liver biopsy in these patients shows steatosis, swollen hepatocytes containing eosinophilic inclusion (Mallory) bodies, and a prominent neutrophilic inflammatory cell infiltrate [the-hospitalist.org]

[…] average consumption in one study was 100 g/day (the equivalent of 10 drinks per day). 1 The typical patient presents with recent onset of jaundice, ascites, and proximal muscle [the-hospitalist.org]

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Bacterial Myositis

Muscle biopsy reveals inclusion bodies i.e. rimmed vacuoles formed due to the collection of abnormal proteins. [kenhub.com]

The muscle biopsy specimen demonstrated an inflammatory infiltrate. No inclusion bodies or viral particles were seen. [atmph.org]

T1 W magnetic resonance imaging show fatty replacement of hamstring muscles. [kenhub.com]

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Left Ventricular Noncompaction

Muscle biopsy of myofibrillar myopathies See the list below. [emedicine.medscape.com]

Light microscopy: Trichrome-stained tissue shows single or multiple areas of blue-red amorphous material described as hyaline structures, cytoplasmic bodies, or inclusions [emedicine.medscape.com]

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Oculopharyngeal Muscular Dystrophy

Histological and histochemical studies of muscle biopsy showed nonspecific myopathic changes; no "ragged-red" fibers were seen. [ncbi.nlm.nih.gov]

A muscle biopsy specimen in Case 2 showed abundant rimmed vacuoles and abnormal filaments 13-19 nm in diameter in the sarcoplasm, usually reported to occur in inclusion body [ncbi.nlm.nih.gov]

Electron microscopy demonstrated bizarre large mitochondria with abnormal cristae, but no intranuclear inclusion bodies. [ncbi.nlm.nih.gov]

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Secondary Myopathy

[…] to the ones seen in inclusion body myositis (IBM). [sites.google.com]

CK and aldolase levels are normal Muscle biopsy is not necessary for the diagnosis, but if obtained, it would show chronic myopathic features and red-rimmed vacuoles similar [sites.google.com]

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MELAS Syndrome

There were no ragged-red fibers, but paracrystalline inclusion bodies were shown in the muscle biopsies under electron microscopic examination. [ncbi.nlm.nih.gov]

Brain magnetic resonance images showed multiple increased signal intensities over the left frontal, parietal and temporal areas. [ncbi.nlm.nih.gov]

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Polymyositis

Furthermore, the muscle biopsy in sIBM often shows the presence of inclusion bodies and/or mitochondrial alterations by modified Gomori trichrome staining or electron microscopy [empendium.com]

Muscle biopsies showing rimmed vacuoles, whose histology suggests cytoplasm inclusion bodies were excluded intending to exclude the cases of inclusion-bodies myositis 14. [doi.org]

The muscle biopsy specimen demonstrated an inflammatory infiltrate. No inclusion bodies or viral particles were seen. [atmph.org]

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Muscular Dystrophy-Dystroglycanopathy Type C14

A muscle biopsy will show ragged-red fibers which contain accumulations of glycogen and neutral lipids. [lecturio.com]

Inflammatory Myopathies These are a group of diseases including polymyositis, dermatomyositis, inclusion body myositis and necrotizing autoimmune myopathy. [lecturio.com]

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Limb-Girdle Muscular Dystrophy Type 1E

A muscle biopsy will show ragged-red fibers which contain accumulations of glycogen and neutral lipids. [lecturio.com]

Muscle biopsy of myofibrillar myopathies See the list below. [emedicine.medscape.com]

Inflammatory Myopathies These are a group of diseases including polymyositis, dermatomyositis, inclusion body myositis and necrotizing autoimmune myopathy. [lecturio.com]

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