Create issue ticket

162 Possible Causes for Muscle Biopsy showing Variation In Fiber Size, Muscle Biopsy Shows Dystrophic Changes, Onset between 6 and 14 Years

  • Limb-Girdle Muscular Dystrophy Type 2B

    Dystrophies are a group of non-inflammatory hereditary conditions which show dystrophic changes (increased connective tissue, fiber splitting) on biopsy without degeneration[lecturio.com] EMG showed myopathic changes and skeletal muscle biopsies showed severe myopathic changes with variation of fiber size, fiber splitting, increased connective tissue, and some[checkorphan.org] […] in morphology of muscles.[lecturio.com]

    Missing: Onset between 6 and 14 Years
  • Congenital Merosin-Positive Muscular Dystrophy

    Muscle biopsy showed dystrophic changes with absent staining for merosin.[pediatricneurosciences.com] (Top) Muscle biopsy showing variation in muscle fiber size with atrophic and hypertrophic fibers.[myslide.es] Muscle biopsy shows dystrophic changes. While rare in North America, the condition is common in Japan with an incidence approaching 40% of DMD (93).[academlib.com]

    Missing: Onset between 6 and 14 Years
  • Distal Myopathy Type 3

    The electromyography showed myopathic pattern and the muscle biopsy disclosed dystrophic changes with absence of dysferlin.[ruralneuropractice.com] Figure 2 Immunohistochemistry, immunoblotting and molecular genetic analysis. ( A ) Micrograph of the muscle biopsy of the right gastrocnemius muscle showing markedly increased[jmedicalcasereports.biomedcentral.com] Age of onset of initial symptoms varied between patients: In family A (Fig. 1A ), while patient 6 was symptomatic already at 2 years of age, patients 1, 5 and 7 recall initial[bmcmedgenet.biomedcentral.com]

  • Limb-Girdle Muscular Dystrophy Type 2G

    Reference work entry DOI: 10.1007/978-3-540-29676-8_2615 Synonyms Telethoninopathy Definition and Characteristics Autosomal recessive, relatively mild form of progressive neuromuscular disorder with a wide spectrum of inter- and intra-familial clinical variability. The age at onset ranges from 9 to 15 years old and[…][link.springer.com]

    Missing: Onset between 6 and 14 Years
  • Limb-Girdle Muscular Dystrophy

    Muscle biopsy showed dystrophic changes without inflammation with reduced immunoreactivity to an antibody against sugar chain (VIA4-1) of alpha-dystroglycan.[ncbi.nlm.nih.gov] Muscle biopsy can show diffuse variation in fiber size, necrosis, regeneration and fibrosis.[dnatesting.uchicago.edu] Early motor milestones: Most normal; Toe walking common Range: 2 to 45 years; Median 14 to 20 years; 71% between 6 to 18 years Weakness: Proximal legs; Rectus abdominus No[neuromuscular.wustl.edu]

  • Congenital Generalized Lipodystrophy Type 4

    Pathological studies on biopsied muscle disclosed mild dystrophic change and highly reduced expression of PTRF-CAVIN.[ncbi.nlm.nih.gov] Biopsied skeletal muscles from P1–P5 showed consistent findings, with chronic dystrophic changes including marked variation in muscle fiber size, increased number of fibers[jci.org] Muscle biopsy, after informed parental consent, showed moderate variation in fiber size, fibers with central nuclei, and mild endomysial fibrosis (Figure 3 B).[bmcmedgenet.biomedcentral.com]

    Missing: Onset between 6 and 14 Years
  • Becker Muscular Dystrophy

    Muscle biopsy showed dystrophic changes. He had comorbidity with dystonia, slight mental retardation, low stature and neuropathy.[ncbi.nlm.nih.gov] His creatine phosphokinase was raised, and a muscle biopsy specimen showed non-specific dystrophic changes.[ncbi.nlm.nih.gov] Muscle biopsy revealed mild myopathic features including variation in fiber size and a few necrotic and regenerating muscle fibers.[doi.org]

    Missing: Onset between 6 and 14 Years
  • Congenital Muscular Dystrophy Type 1A

    Muscle biopsy showed dystrophic changes with absent staining for merosin.[pediatricneurosciences.com] Muscle biopsy in all our patients showed a dystrophic picture with extensive pericellular fibrosis, fiber size variation, and rounding.[annalsofian.org] His echocardiogram showed normal findings [Figure 2]. His serum CPK level was 2120 U/l and MRI of the brain showed similar findings with other patients.[pediatricneurosciences.com]

    Missing: Onset between 6 and 14 Years
  • Muscular Dystrophy-Dystroglycanopathy Type B5

    Cranial magnetic resonance imaging showed cerebellar cysts and hypoplasia of the vermis and muscle biopsy showed dystrophic changes.[cags.org.ae] In some individuals with CMD, muscle biopsy may only show fiber size variation with absence of or only mild manifestations of fibrosis, necrosis, or regeneration [ Wang et[ncbi.nlm.nih.gov] . • Skeletal muscle biopsy shows dystrophic change and additional immunohistochemical abnormalities of variable specificity.[medlink.com]

    Missing: Onset between 6 and 14 Years
  • Duchenne Muscular Dystrophy

    Clinical diagnosis of DMD included progressive proximal weakness, highly elevated creatine kinase levels, and a muscle biopsy showing significant dystrophic changes including[ncbi.nlm.nih.gov]

    Missing: Onset between 6 and 14 Years

Similar symptoms