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3,350 Possible Causes for Muscle Biopsy Shows Inflammation with T Cells, Vacuolization

  • Inclusion Body Myositis

    The coexistence of ring fibres, rimmed vacuoles and inclusion-body myositis-type inclusions in a child with congenital myopathy has not been previously reported.[] Abstract OBJECTIVE: Sporadic inclusion body myositis (sIBM) pathogenesis is unknown; however, rimmed vacuoles (RVs) are a constant feature.[] Rimmed vacuoles were found in 49 patients (60.5%).[]

  • Myositis

    ", although the extent of myofibers having classic rimmed vacuoles varies ( Dubowitz: Muscle Biopsy: A Practical Approach, 2013, 4th Edition ) The vacuoles disrupt the myofiber[] Examination of a repeat muscle biopsy specimen showed occasional degenerating myofibers and perivascular inflammation.[] Inclusion body myositis is frequently misdiagnosed as polymyositis when rimmed vacuoles are absent on muscle biopsy, and a careful neuromuscular evaluation is not performed[]

  • Hibernoma

    Pathologic findings include sheets of multivacuolated cells with centrally placed nuclei and numerous tiny surrounding cytoplasmic vacuoles overlying bony trabeculae.[] Cytology [ edit ] The fine needle aspiration smears show small, round, brown fat-like cells, with uniform, small cytoplasmic vacuoles and regular, small, round nuclei.[] Granular cell tumour : Distinguished by complete absence of lipid cytoplasmic vacuoles. The granular cells are diffusely positive with S-100 protein.[]

    Missing: Muscle Biopsy Shows Inflammation with T Cells
  • Pleomorphic Liposarcoma

    vacuole or vacuoles Must be sharply defined Must indent and distort nucleus May be focal or widespread S100 may highlight lipoblasts May contain cytoplasmic eosinophilic[] vacuoles Sarcomatous component contains atypical spindled, round, and pleomorphic tumor cells Numerous mono- and multinucleated tumor giant cells High degree of nuclear atypia[] We consistently identified numerous lipoblasts as well as micro and macrovesicular fat vacuoles in the background of cellular, pleomorphic sarcomatoid neoplasms.[]

    Missing: Muscle Biopsy Shows Inflammation with T Cells
  • Oculo-Pharyngo-Distal Myopathy

    Muscular dystrophy changes with rimmed vacuoles were the main histopathological changes.[] Myopathological findings showed rimmed vacuoles with varying degrees of muscular dystrophic changes.[] Histological features included basophilic-rimmed vacuoles, but the typical OPMD intranuclear filaments were absent.[]

    Missing: Muscle Biopsy Shows Inflammation with T Cells
  • Polymyositis

    Histologic Findings Muscle biopsy shows muscle fibers in varying stages of inflammation, necrosis, and regeneration.[] KEYWORDS: anti-Ku antibody; dropped head syndrome; rimmed vacuole; scleroderma-polymyositis overlap syndrome[] Arahata and Engel state that all their patients with a diagnosis of inclusion body myositis had the typical histological findings, including vacuoles and filamentous inclusions[]

  • Danon Disease

    […] clusters of autophagic vacuoles, indicative of autolysosomes.[] However, the first muscle biopsy with large cytoplasmic vacuoles confused the diagnosis and led to the second biopsy that allowed for the final diagnosis.[] Two patients underwent heart transplantation; histology of explanted hearts demonstrated severe interstitial fibrosis, hypertrophic cardiomyocytes with cytoplasmic vacuoles[]

    Missing: Muscle Biopsy Shows Inflammation with T Cells
  • Hemangioblastoma

    Microscopically, the neoplasm was seen to be composed of vascular channels associated with foamy stromal cells, containing clear cytoplasmic vacuoles.[] Tumor was composed of numerous capillaries and stromal cells with cytoplasmic vacuolization.[] But the tumor cells commonly show lipid cytoplasmic vacuoles; mitotic activity, infiltrative growth and vascular invasion are often identifiable.[]

    Missing: Muscle Biopsy Shows Inflammation with T Cells
  • Toxoplasmosis

    (White bars: smooth vacuoles; grey bars: rough vacuoles, black bars: disrupted vacuoles.) Nuclei were stained with DAPI.[] The autophagy regulator beclin 1 was concentrated in the vicinity of the parasitophorous vacuole in infected cells.[] During invasion Toxoplasma creates the parasitophorous vacuole, a subcellular compartment that acts as an interface between the parasite and host, and serves as a platform[]

    Missing: Muscle Biopsy Shows Inflammation with T Cells
  • Distal Myopathy Type 3

    Tubulofilamentous inclusion, myeloid bodies, and autophagic vacuoles in the area corresponding to rimmed vacuoles ( d ; bar 1 μm).[] Yonsei Medical Journal. 2013; 54(3): 578-582 [Pubmed] 7 Distal myopathy with rimmed vacuoles and inflammation: A genetically proven case Kannan, M.A. and Challa, S. and Urtizberea[] The CK is slightly high and there are no vacuoles in the muscular biopsy.[]

    Missing: Muscle Biopsy Shows Inflammation with T Cells

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