Muscle Hypertrophy: Causes & Reasons

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Possible Causes for Muscle Hypertrophy

Myotonia Congenita

Two patients showed muscle bulk hypertrophy of thighs and calves in line with the clinical appearance. [ncbi.nlm.nih.gov]

Muscle hypertrophy in myotonia congenita Free B Varkey, L Varkey Indo-American Hospital, Chemmanakary, Vaikom, Kerala, India Correspondence to:  Dr B Varkey;  bobvarkey{at [jnnp.bmj.com]

Affected individuals had isolated myotonia without muscle weakness, hypotrophy, or hypertrophy. [mda.org.au]

Paramyotonia Congenita

The typical clinical picture of MC is muscle stiffness (myotonia) and muscle hypertrophy. [content.iospress.com]

This "overuse" of the muscle results in the muscle becoming enlarged and bulky (called muscle hypertrophy). [encyclopedia.com]

[…] weakness Muscular weakness 0001324 Skeletal muscle hypertrophy Increased skeletal muscle cells 0003712 Showing of 23 | Last updated: 2/1/2021 Find a Specialist Find a Specialist [rarediseases.info.nih.gov]

Non-Dystrophic Myotonia

muscle hypertrophy, psychomotor retardation, and fatal outcome are evocative of a distinct clinical subtype. [uniprot.org]

It is postulated that permanent excitability gives rise to constant mild muscle activity, resulting in muscle hypertrophy. [checkorphan.org]

The typical clinical picture of MC is muscle stiffness (myotonia) and muscle hypertrophy. [content.iospress.com]

Muscular Dystrophy-Dystroglycanopathy Type A2

CMD with muscle hypertrophy and respiratory failure. (14)Ullrich congenital muscular dystrophy – present at birth is weakness, poor muscle tone, will have some deformity [mobilephysiotherapyclinic.in]

[…] in the muscle, and frequently calf hypertrophy. [what-when-how.com]

Hypertrophy of the calf is common, and the tongue muscles may become enlarged. [emedicine.medscape.com]

Pyloric Stenosis

A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants. [fpnotebook.com]

We present this series as an illuminating depiction of the development of muscle hypertrophy in patients with pyloric stenosis. [ncbi.nlm.nih.gov]

Definition (NCI) Narrowing of the pyloric lumen caused either by hypertrophy of the surrounding muscles or tissue scarring due to a chronic peptic ulcer. [fpnotebook.com]

Hypertrophic Cardiomyopathy

1471-2261-14-34-S1.ogv 1,7 s, 1 280 × 720; 333 KB Riproduci file multimediale Solitary-accessory-and-papillary-muscle-hypertrophy-manifested-as-dynamic-mid-wall-obstruction-and [commons.wikimedia.org]

[ edit ] University of California Muscle Physiology Home Page: Hypertrophy [en.wikipedia.org]

The main feature of Hypertrophic Cardiomyopathy is an excessive thickening of the heart muscle (hypertrophy literally means to thicken). [ineaia.tripod.com]

Acquired Hypertrophic Pyloric Stenosis

A common form is due to muscle hypertrophy (pyloric stenosis, hypertrophic) seen in infants. [icd10data.com]

HIATUS HERNIA, PYLORIC MUSCLE HYPERTROPHY AND CONTRACTED ... 21.02.2013 · The incidence of a contracted prepyloric segment in cases of hiatus hernia in adults was determined [weightssimpson.tk]

The classic radiographic signs are the “string sign” and the “shoulder sign” caused by the hypertrophied muscle protruding into the gastric channel. [ipeg.org]

Congenital Pyloric Stenosis

The circular muscle hypertrophies and the thickened muscle reduces the lumen of the pyloric channel and also elongates it. [sonoworld.com]

A common form is due to muscle hypertrophy (PYLORIC STENOSIS, HYPERTROPHIC) seen in infants. [fpnotebook.com]

Hypertrophy of the musculature of pyloric antrum, especially the circular muscle fibres, causing failure of pylorus to relax. Duodenum is normal. [medicinembbs.blogspot.com]

Muscular Dystrophy-Dystroglycanopathy Type C14

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

The clinical picture consists of mostly symmetrical, atrophic muscular dystrophy, with rare muscle hypertrophy. [radiopaedia.org]

Overgrowth (hypertrophy) of the calf muscle may also occur. [rarediseases.org]

Limb-Girdle Muscular Dystrophy Type 2C

Muscle wasting affected mainly limb-girdle and trunk muscles; calf muscle hypertrophy was usually present. [link.springer.com]

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

Myoedema, or mounding of the muscle after percussion, may be observed. Patients may also have proximal weakness, muscle hypertrophy, or myalgias. [checkorphan.org]

Limb-Girdle Muscular Dystrophy Type 2E

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

The clinical picture consists of mostly symmetrical, atrophic muscular dystrophy, with rare muscle hypertrophy. [radiopaedia.org]

Showing of 23 | 30%-79% of people have these symptoms Broad-based gait Wide based walk 0002136 Calf muscle hypertrophy Increased size of calf muscles 0008981 Delayed speech [rarediseases.info.nih.gov]

Limb-Girdle Muscular Dystrophy Type 2J

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

The clinical picture consists of mostly symmetrical, atrophic muscular dystrophy, with rare muscle hypertrophy. [radiopaedia.org]

hypertrophy Increased size of calf muscles 0008981 EMG: myopathic abnormalities 0003458 Flexion contracture Flexed joint that cannot be straightened 0001371 Juvenile onset [rarediseases.info.nih.gov]

Limb-Girdle Muscular Dystrophy Type 2Q

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

The clinical picture consists of mostly symmetrical, atrophic muscular dystrophy, with rare muscle hypertrophy. [radiopaedia.org]

Overgrowth (hypertrophy) of the calf muscle may also occur. [rarediseases.org]

Muscular Dystrophy-Dystroglycanopathy Type C9

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

The clinical picture consists of mostly symmetrical, atrophic muscular dystrophy, with rare muscle hypertrophy. [radiopaedia.org]

Overgrowth (hypertrophy) of the calf muscle may also occur. [rarediseases.org]

Limb-Girdle Muscular Dystrophy Type 2F

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

The clinical picture consists of mostly symmetrical, atrophic muscular dystrophy, with rare muscle hypertrophy. [radiopaedia.org]

Symptoms may additionally include: enlargement (hypertrophy) of the calf muscle and tongue, diseases of the heart muscle ( cardiomyopathy ), and respiratory abnormalities. [rarediseases.info.nih.gov]

Limb-Girdle Muscular Dystrophy Type 2G

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

hypertrophy Increased size of calf muscles 0008981 Difficulty climbing stairs Difficulty walking up stairs 0003551 Difficulty running 0009046 Difficulty walking Difficulty [rarediseases.info.nih.gov]

Overgrowth (hypertrophy) of the calf muscle may also occur. [rarediseases.org]

Muscular Dystrophy-Dystroglycanopathy Type C3

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

The clinical picture consists of mostly symmetrical, atrophic muscular dystrophy, with rare muscle hypertrophy. [radiopaedia.org]

Muscle hypertrophy, especially enlarged calves, is a common feature as are cramps and rippling muscle disease. [mdfgauteng.org]

Muscular Dystrophy-Dystroglycanopathy Type C5

Onset within the first few years of life predicts a Duchenne-like progression with muscle hypertrophy in the thigh and tongue, and lost independent walking during second decade [egl-eurofins.com]

muscle hypertrophy Increased size of calf muscles 0008981 Generalized hypotonia Decreased muscle tone Low muscle tone [ more ] 0001290 Pelvic girdle muscle weakness 0003749 [rarediseases.info.nih.gov]

Overgrowth (hypertrophy) of the calf muscle may also occur. [rarediseases.org]

Limb-Girdle Muscular Dystrophy Type 1H

Overgrowth (hypertrophy) of the calf muscle may also occur. [rarediseases.org]

Earlier onset of the disease was observed in a group of patients presenting with muscle weakness and/or calf hypertrophy, and/or occasionally high CK and lactate serum levels [moh-it.pure.elsevier.com]

[…] fiber atrophy Limb muscle weakness Calf muscle hypertrophy Difficulty running Quadriceps muscle atrophy Elevated alkaline phosphatase Limb-girdle muscular dystrophy Muscle [mendelian.co]

Limb-Girdle Muscular Dystrophy Type 2B

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

The clinical picture consists of mostly symmetrical, atrophic muscular dystrophy, with rare muscle hypertrophy. [radiopaedia.org]

Our case describes a patient with joint and muscle pain, with mild calf and thigh muscle hypertrophy. [ped-rheum.biomedcentral.com]

Schwartz-Jampel Syndrome

Clinical manifestations of this disease began at birth with marked generalized muscle hypertrophy, stiffness, myotonia and multiple skeletal deformities. [ncbi.nlm.nih.gov]

hypertrophy, clinical myotonia, and continuous muscle fiber activity. [ncbi.nlm.nih.gov]

Schwartz-Jampel syndrome generally presents in childhood with short stature, limited joint mobility, masklike facies with blepharophimosis, myotonia, and often muscle hypertrophy [ncbi.nlm.nih.gov]

Papillary Muscle Disorder

Not until recently, morphological papillary muscle anomalies without features of phenotypic LV hypertrophy (isolated papillary muscle hypertrophy) had gradually been recognized [bmccardiovascdisord.biomedcentral.com]

【解】不随意肌 muscle hypertrophy. [hujiang.com]

The left ventricular cavity was reduced by the anterior displacement of the hypertrophied papillary muscle. [heart.bmj.com]

Myotonia Congenita Type Thomsen

Muscle hypertrophy is a common sign. [ncbi.nlm.nih.gov]

Statistics from Altmetric.com Muscle hypertrophy myotonia congenita A 28 year old male presented to our neurology service with stiffness of a few years’ duration in all muscles [jnnp.bmj.com]

Affected individuals had isolated myotonia without muscle weakness, hypotrophy, or hypertrophy. [mda.org.au]

Upper Limb Hypertrophy

Neurogenic muscle hypertrophy. J Neurol 1989;236:292-5. 6. Gutmann LA, Gutmann LU, Schochet SS. Spontaneous repetitive discharges and muscle hypertrophy. [ruralneuropractice.com]

Calf muscle hypertrophy in late onset pompe's disease. [amhsjournal.org]

Ogino T, Satake H, Takahara M, Kikuchi N, Watanabe T, Iba K, Ishii S: Aberrant muscle syndrome: hypertrophy of the hand and arm due to aberrant muscles with or without hypertrophy [karger.com]

Congenital Generalized Lipodystrophy Type 4

[…] lordosis, hypertrophy appearance in muscles, hip, knee and ankle joints had limitation of movement and inability to walk. [abstracts.eurospe.org]

Muscle hypertrophy, muscle mounding, mild metabolic complications, and elevated serum creatine kinase levels were observed in these patients. [f1000.com]

Figure 2 Lower limb CT, showing muscle hypertrophy and marked loss of subcutaneous fat. [bmcmedgenet.biomedcentral.com]

Congenital Generalized Lipodystrophy Type 1

All children had widespread absence of adipose tissue from infancy together with apparent muscle hypertrophy and hepatomegaly. [cags.org.ae]

Generalized lipodystrophy syndrome is the association of acanthosis nigricans (AN) with the generalized complete absence of subcutaneous fat and the presence of muscle hypertrophy [emedicine.medscape.com]

The other cardinal signs are acanthosis nigricans, hypertrichosis, and muscle hypertrophy. [ijpd.in]

Erb Muscular Dystrophy

[…] weakness of upper arm and pelvic muscles Assessment-Physical Findings Wide stance and waddling gait Gowers' sign when rising from a sitting or supine position Muscle hypertrophy [quizlet.com]

Overgrowth (hypertrophy) of the calf muscle may also occur. [rarediseases.org]

hypertrophy Especially calf May be generalized Increases with age Most commonly due to: Muscle replacement by fat & connective tissue Some relatively spared muscles may have [neuromuscular.wustl.edu]

Limb-Girdle Muscular Dystrophy Type 2L

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

Overgrowth (hypertrophy) of the calf muscle may also occur. [rarediseases.org]

Muscular Dystrophy-Dystroglycanopathy Type B5

Thus, overexpressing Smad7 suppresses Smad2/3 signaling, promotes muscle hypertrophy and prevents muscle wasting. [aavogen.com]

Muscle weakness, hypertrophy or contractures (including calf and tongue hypertrophy). Note: The mode of presentation and the pattern of muscle involvement. [patient.info]

MDC1C is characterized by early onset, inability to achieve independent ambulation, muscle hypertrophy, marked elevation of serum creatine kinases, no brain involvement, a [dmd.nl]

Limb-Girdle Muscular Dystrophy Type 1E

Myoedema, or mounding of the muscle after percussion, may be observed. Patients may also have proximal weakness, muscle hypertrophy, or myalgias. [checkorphan.org]

Muscle hypertrophy, especially enlarged calves, is a common feature as are cramps and rippling muscle disease. [mdfgauteng.org]

Cardiomyopathy LGMD2E SGCB / βSarcoglycan Early childhood Very high Rapid Tongue hypertrophy; Muscle hypertrophy Cardiomyopathy LGMD2F SGCD / δSarcoglycan Early childhood [now.aapmr.org]