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20 Possible Causes for Muscle Hypotonia, Poor Feeding, Wide Space Between the First and Second Toe

  • Dubowitz Syndrome

    feeding.[ncbi.nlm.nih.gov] Low or weak muscle tone 0001252 Neuroblastoma Cancer of early nerve cells 0003006 Otitis media Middle ear infection 0000388 Pes planus Flat feet Flat foot [ more ] 0001763[rarediseases.info.nih.gov] Abdominal/Gastrointestinal characteristics can include poor feeding, frequent vomiting, chronic diarrhea, and/or gastroesophageal reflux .[dubowitzsyndrome.net]

  • Down Syndrome

    Marked hypotonia or other feeding difficulties should prompt a radiographic swallowing assessment.[patient.info] From Wikidata Jump to navigation Jump to search chromosomal disease characterized by flat-looking facial features and weak muscle tone (hypotonia) in infancy and is caused[wikidata.org] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org]

  • Craniofrontonasal Dysplasia

    difficulty.[mjdrdypu.org] Some individuals affected by CFND may also have diminished muscle tone (hypotonia), developmental delays, hearing impairment (sensorineural deafness), a sunken chest (pectus[rarediseases.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Weaver Syndrome

    Her inadequate nutrition was a result of feeding difficulties during infancy.[ncbi.nlm.nih.gov] Other common symptoms include hypertonia (increased muscle tone, tight muscles) as well as hypotonia (decreased muscle tone, "floppy" muscles) and a hoarse low-pitched cry[encyclopedia.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Russell-Silver Syndrome

    80%-99% of people have these symptoms Blue sclerae Whites of eyes are a bluish-gray color 0000592 Cachexia Wasting syndrome 0004326 Feeding difficulties Feeding problems Poor[rarediseases.info.nih.gov] Gastrointestinal/metabolic difficulties Feeding difficulties during infancy, including gastro-oesophageal reflux, oesophagitis, food aversion, poor appetite and faltering[patient.info] Feeding difficulty after birth causes poor appetites, hypoglycemia, thin physical stature.[syndromespedia.com]

  • Ring Chromosome 10

    She had no feeding difficulties. Abdominal organs were without structural abnormalities.[molecularcytogenetics.biomedcentral.com] Low or weak muscle tone 0001252 Pectus excavatum Funnel chest 0000767 Renal hypoplasia/aplasia Absent/small kidney Absent/underdeveloped kidney [ more ] 0008678 Sandal gap[rarediseases.info.nih.gov] . _2 46, XY, upd(7), r(7)(p11.2q21) pat Russell-Silver syndrome, intrauterine growth retardation, feeding difficulties, retarded bone age, growth retardation, motor development[chr7.org]

  • Atelosteogenesis Type 2

    Surgical intervention is indicated for articulation problems and also for feeding difficulties (poor suckling), dental problems (spreading of the lower incisor teeth), or[oralmaxillo-facialsurgery.blogspot.com] He had difficulty in walking, mild proximal muscular hypotonia in the lower extremities and hyperactive deep tendon reflexes.[nature.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov]

  • Macrocephaly-Developmental Delay Syndrome

    On the basis of initial clinical indications including truncal hypotonia, poor weight gain, feeding difficulties, relative macrocephaly, and some facial features, it was thought[clinchem.aaccjnls.org] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] Cohen Syndrome Malformations of the head and facial (craniofacial) area, eye (ocular) abnormalities, diminished muscle tone (hypotonia), obesity, abnormally narrow hands and[apraxia-kids.org]

  • Cutis Laxa

    Initial poor feeding improved spontaneously after a week and the baby was discharged.[jmg.bmj.com] Individuals with EFEMP2 -related cutis laxa usually present with muscle hypotonia. Other common findings are arachnodactyly, joint laxity, and pectus deformities.[ncbi.nlm.nih.gov] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br]

  • Multiple Endocrine Neoplasia Type 2B

    Feeding difficulties--poor suck to the point of failure to thrive--were present in the neonatal periods of seven of our nine patients who had MEN 2b.[ncbi.nlm.nih.gov] Mucosal neuromas à GI symptoms, muscle hypotonia, chronic constipation due to hyperplasia of autonomic ganglia in the intestinal wall.[almostadoctor.co.uk] Figure 3 The first toe is longer than the others and there is a wide space between the first and second toe.[ijponline.biomedcentral.com]

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